Chiral Polymer-induced Hydroxyapatite for Promoting Bone Regeneration

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101460 - 101460

Published: Jan. 5, 2025

Chirality is one of the basic characteristics living matter, yet effect chiral polymers on osteogenesis seldom studied. Thus, it necessary to deeply recognize behaviors in osteogenic processes, which can be beneficial for development bone repair materials. In this work, hydroxyapatite (HAP) was constructed simply using poly(levorotatory/dextral-tartaric acid) as guest transfer system. We studied influence HAPs migration and differentiation pre-osteoblasts, angiogenesis endothelial cell vitro. The results showed that poly(levorotatory-tartaric acid)-induced HAP did promote vascular remodeling exhibited excellent impact osteogenetic by improving related gene protein expression, whereas no significant change observed poly(dextral-tartaric or poly(racemic-tartaric induced HAP, respectively. This study highlighted effects potential, laid groundwork biomaterials regeneration.

Language: Английский

Titanium alloy-based hydroxyapatite composites in sports injury repair: Preparation, Application, and Prospects

Journal of Alloys and Compounds, Journal Year: 2025, Volume and Issue: unknown, P. 180416 - 180416

Published: April 1, 2025

Language: Английский