Graphene Oxide Nanosheets for Delivery of RNAi and Plant Immune Stimulation for Sustained Protection against Plant Viruses DOI
Hongbao Zhang, Guangjin Fan, Dong Leng

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Given the dearth of effective antiviral drugs, exogenous delivery dsRNA for RNAi against plant viral diseases holds great promise. Here, we present an approach utilizing graphene oxide nanosheets (GONs) on mature leaves via a spray. Our method achieves rapid and sustained gene knockdown, reducing level target to 46% by day 2, continuously releases at least 6 days. The coupling GONs with specific fragments coat protein replicase exhibited superior effect compared RNA-dependent movement protein. fragment even has 87.2% protection TMV. Moreover, nanocomplex GONs@dsRNA can also stimulate immunity through bursts reactive oxygen species without harming growth. Overall, our findings robust convenient tool virus control.

Language: Английский

Graphene oxide reinforced tough elastomeric nanocomposite semi-interpenetrating network hydrogel for pH-dependent controlled release of calcium channel blocker drug DOI
Ashish Tiwari, Neeta Gupta, Reena Negi

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142033 - 142033

Published: March 1, 2025

Language: Английский

Citations

0
Carbon nanotubes-based electrode materials for dopamine sensing and platinum-free dye-sensitized solar cells: A mini review DOI
Khursheed Ahmad, Waseem Raza,

Tae Hwan Oh

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113352 - 113352

Published: March 1, 2025

Language: Английский

Citations

0
Graphene Oxide Nanosheets for Delivery of RNAi and Plant Immune Stimulation for Sustained Protection against Plant Viruses DOI
Hongbao Zhang, Guangjin Fan, Dong Leng

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Given the dearth of effective antiviral drugs, exogenous delivery dsRNA for RNAi against plant viral diseases holds great promise. Here, we present an approach utilizing graphene oxide nanosheets (GONs) on mature leaves via a spray. Our method achieves rapid and sustained gene knockdown, reducing level target to 46% by day 2, continuously releases at least 6 days. The coupling GONs with specific fragments coat protein replicase exhibited superior effect compared RNA-dependent movement protein. fragment even has 87.2% protection TMV. Moreover, nanocomplex GONs@dsRNA can also stimulate immunity through bursts reactive oxygen species without harming growth. Overall, our findings robust convenient tool virus control.

Language: Английский

Citations

0