Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system DOI
Wessam H. Abd-Elsalam, Abdulaziz Mohsen Al-mahallawi, Amal Makhlouf

et al.

DARU Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: 32(2), P. 705 - 714

Published: Oct. 8, 2024

Language: Английский

Development and evaluation of chitosan-coated virgin coconut oil-asiatic acid-loaded nanoemulgel for enhanced wound management DOI

Manohar Mahadev,

S Ballal,

Amitha Shetty

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 299, P. 140097 - 140097

Published: Jan. 21, 2025

Language: Английский

Citations

2

Vesicular Carriers for Phytochemical Delivery: A Comprehensive Review of Techniques and Applications DOI Creative Commons
Shery Jacob, Fathima Sheik Kather, Sai H. S. Boddu

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 464 - 464

Published: April 2, 2025

Natural substances, especially those derived from plants, exhibit a diverse range of therapeutic benefits, such as antioxidant, anti-inflammatory, anticancer, and antimicrobial effects. Nevertheless, their use in clinical settings is frequently impeded by inadequate solubility, limited bioavailability, instability. Nanovesicular carriers, liposomes, niosomes, ethosomes, transferosomes, transethosomes, cubosomes, have emerged innovative phytochemical delivery systems to address these limitations. This review highlights recent developments vesicular nanocarriers for delivery, emphasizing preparation techniques, composition, applications, the future potential systems. Phytosomes, along with key advantages various are extensively described. Various vitro vivo characterization techniques utilized evaluating nanovesicular carriers summarized. Completed trials patents granted nanovesicles encapsulating phytochemicals designed systemic tabulated. Phytochemical via faces challenges low stability, active loading, scalability issues, high production costs. Additionally, immune clearance regulatory hurdles hinder application, requiring improved carrier design formulation techniques.

Language: Английский

Citations

1

Nanomaterials for the Treatment of Lung Cancer: The Role of Natural Products DOI
Luis Francisco Salomé-Abarca, Daniel Hernández‐Patlan, Bruno Solís-Cruz

et al.

Interdisciplinary cancer research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

Physicochemical Profile of Yucca filamentosa and a Comparative Chemical Profiling Study of its Mother Tinctures Prepared in and Outside India DOI

Bibaswan Biswas,

Satyajit Maity,

Paulami Majumdar

et al.

Homœopathic Links, Journal Year: 2025, Volume and Issue: unknown

Published: May 7, 2025

Abstract Yucca filamentosa is primarily used in homeopathy for treating gastric ailments, supported by its saponin content. Despite being exotic to India with limited availability, mother tincture widely accessible the country. Given these factors, assessing quality of medicines crucial. Therefore, alongside pharmacopeial standardization, a comparative chemical profiling study was conducted on tinctures sourced from plants grown (OM), those produced (IM), and manufactured abroad (AM). The parameters raw drug, such as loss drying, different ash values, extractive values various solvents, volatile oil content, were measured. Additionally, phytochemical screening drug solvents performed. Subsequently, physicochemical including organoleptic characteristics, sediments, total solids, ultraviolet–visible absorption spectra OM, IM, AM compared. Further qualitative high-performance thin-layer chromatography (HPTLC) analysis conducted. data reported first time. revealed significant differences. comparison three (OM, AM) highlighted substantial variations, underscoring need more rigorous biological evaluations.

Language: Английский

Citations

0

Formulation and Characterization of RBCS Coated Carboplatin Loaded Nano‐Liposomal Formulation for Managing Breast Cancer DOI
Akhilesh Dubey,

Faby Raju,

Cynthia Lizzie Lobo

et al.

Drug Development Research, Journal Year: 2024, Volume and Issue: 85(8)

Published: Nov. 19, 2024

Cell membrane-coated Nano-Liposomes (CM-NLPs) offer a promising approach that combines the advantages of both host cells and synthetic nano-liposomes (NLPs). This technique involves coating liposomes with red blood cell (RBC) membranes to enhance their functionality. In this study, novel carboplatin-loaded NLPs (CP-NLPs) were formulated using phospholipids (Soya Phosphatidyl Choline) cholesterol through thin-film hydration method, optimized 3

Language: Английский

Citations

1

Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system DOI
Wessam H. Abd-Elsalam, Abdulaziz Mohsen Al-mahallawi, Amal Makhlouf

et al.

DARU Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: 32(2), P. 705 - 714

Published: Oct. 8, 2024

Language: Английский

Citations

0