MicroRNA expression and their molecular targets in food allergies: a systematic review DOI Creative Commons
Tekan S. Rana,

Rishipal R. Bansode,

Jyoti Rana

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: May 12, 2025

MicroRNAs (miRs) play an essential role in adaptive and innate immune systems by regulating the development of cells. However, detailed studies miRs' food allergies are scarce compared to those other allergic or non- diseases. This systematic review aims study miRs expression its (FAs) determine signature FAs. Research articles published since 2015 were selected from various databases: Scopus, PubMed, ScienceDirect, Web Science. Randomized clinical trials, observational studies, vivo assessed via Cochrane Risk Bias 2 tool, Newcastle-Ottawa scale, SYRCLE method, respectively. The characteristics included population characteristics, experimental details extracted, data synthesized narratively. MiRs had been investigated context cow milk allergy (CMA) peanut (PA) through both trials. Clinical trials multiple combined foods, individual foods (such as milk, peanut, what), drugs venom, while conducted on egg, allergies. MiR-146a, miR- 155, miR-30a-5p common between Moreover, few commonly studied different types In miR-143-3p was non-celiac wheat sensitivity (NCWS), miR-155 CMA egg studies. Furthermore, same varied their molecular target effect depending type allergy. determination for therapeutic purpose is initial stage. For allergies, next-generation sequencing (NGS), validation polymerase chain reaction (PCR), molecule RNA interference (RNAi) should be focus future order reliable

Language: Английский

MicroRNA expression and their molecular targets in food allergies: a systematic review DOI Creative Commons
Tekan S. Rana,

Rishipal R. Bansode,

Jyoti Rana

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: May 12, 2025

MicroRNAs (miRs) play an essential role in adaptive and innate immune systems by regulating the development of cells. However, detailed studies miRs' food allergies are scarce compared to those other allergic or non- diseases. This systematic review aims study miRs expression its (FAs) determine signature FAs. Research articles published since 2015 were selected from various databases: Scopus, PubMed, ScienceDirect, Web Science. Randomized clinical trials, observational studies, vivo assessed via Cochrane Risk Bias 2 tool, Newcastle-Ottawa scale, SYRCLE method, respectively. The characteristics included population characteristics, experimental details extracted, data synthesized narratively. MiRs had been investigated context cow milk allergy (CMA) peanut (PA) through both trials. Clinical trials multiple combined foods, individual foods (such as milk, peanut, what), drugs venom, while conducted on egg, allergies. MiR-146a, miR- 155, miR-30a-5p common between Moreover, few commonly studied different types In miR-143-3p was non-celiac wheat sensitivity (NCWS), miR-155 CMA egg studies. Furthermore, same varied their molecular target effect depending type allergy. determination for therapeutic purpose is initial stage. For allergies, next-generation sequencing (NGS), validation polymerase chain reaction (PCR), molecule RNA interference (RNAi) should be focus future order reliable

Language: Английский

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