Integration of Circular Economy and Urban Metabolism for a Resilient Waste-Based Sustainable Urban Environment
Urban Science,
Journal Year:
2024,
Volume and Issue:
8(4), P. 175 - 175
Published: Oct. 16, 2024
An
unsustainable
rate
of
resource
production
and
consumption
is
evident
in
urban
environments.
The
absence
innovative
approaches
conjunction
with
the
exponential
urbanization
expansion
global
population
will
inevitably
result
substantial
environmental
consequences.
There
are
two
emerging
alternatives:
circular
economy
(CE)
metabolism
(UM).
integration
these
principles
into
novel
methodology
casts
doubt
on
linear
model
contemporary
economic
systems,
which
includes
extraction,
production,
utilization,
disposal.
In
development
a
distinctive
framework
known
as
metabolism,
current
study
has
illustrated
application
principles.
We
design
this
to
motivate
planners
decision-makers
investigate,
develop,
supervise
ecologically
sustainable
cities.
Scholars
from
variety
academic
disciplines,
intrigued
by
intricacies
planning,
design,
administration,
can
foster
interdisciplinary
collaboration
(CUM)
region.
To
address
research
question,
we
implemented
bibliometric
analysis,
involved
examination
627
pertinent
papers,
utilizing
R
(R
3.6.0+)
statistical
programming
language.
results
emphasize
fundamental
characteristics
significance
CUM
management
refuse.
addition,
findings
underscore
importance
creating
that
incorporates
political
ecology,
CUM,
sustainability,
dimension
waste
metabolism.
It
goal
recycling
informal
sector
strategy
low-
medium-income
countries
(LMICs).
Language: Английский
Maternal Gut Microbiome-Mediated Epigenetic Modifications in Cognitive Development and Impairments: A New Frontier for Therapeutic Innovation
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(24), P. 4355 - 4355
Published: Dec. 17, 2024
Cognitive
impairment
in
various
mental
illnesses,
particularly
neuropsychiatric
disorders,
has
adverse
functional
and
clinical
consequences.
While
genetic
mutations
epigenetic
dysregulations
of
several
genes
during
embryonic
adult
periods
are
linked
to
cognitive
the
composition
diversity
resident
bacteria
gastrointestinal
tract—shaped
by
environmental
factors—also
influence
brain
epigenome,
affecting
behavior
functions.
Accordingly,
many
recent
studies
have
provided
evidence
that
human
gut
microbiota
may
offer
a
potential
avenue
for
improving
deficits.
In
this
review,
we
provide
an
overview
relationship
between
impairment,
alterations
microbiome,
periods.
We
examine
how
factors
beyond
genetics—such
as
lifestyle,
age,
maternal
diet—impact
composition,
diversity,
functionality
consequently
influencing
performance.
Additionally,
explore
microbiome
signatures
biomarkers
predicting
risk
older
adults.
This
article
also
explores
roles
nutritional
deficiencies
programming
disorders
perinatal
period
offspring,
well
promise
microbiome-targeted
therapeutics
with
effects
prevent
or
alleviate
dysfunctions
infants,
middle-aged
adults,
Unsolved
challenges
mitigating
translation
into
practice
discussed,
lastly.
Language: Английский
Molecular symphonies and signalling pathways orchestrated by the gut microbiome in metastatic colorectal cancer (mCRC); a state-of-the-art review
Expert Reviews in Molecular Medicine,
Journal Year:
2024,
Volume and Issue:
26
Published: Jan. 1, 2024
Abstract
The
role
of
oncobiosis,
characterized
by
dysregulated
microbial
ecosystems
associated
with
cancer,
has
been
increasingly
acknowledged
in
promoting
the
metastasis
and
dissemination
tumour
cells.
A
comprehensive
understanding
complex
interactions
between
gut
microbiome
metastatic
colorectal
cancer
(mCRC)
presents
promising
avenues
for
development
innovative
therapeutic
approaches
centred
around
modulating
to
prevent
or
hinder
spread.
In
this
review,
we
aim
provide
a
molecularly
focused
summary
implications
human
metabolites
initiation
advancement
mCRC.
By
elucidating
these
intricate
mechanisms,
strive
establish
foundation
future
research
design
novel
interventions
targeting
combat
devastating
disease.
Language: Английский