Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster DOI Creative Commons
Bhanu Shrestha, Jiun Sang, Suman Rimal

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Dec. 11, 2024

Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied date, the attractiveness of oral acids contingent on concentration. Many carboxylic are attractive at ecologically relevant concentrations but become aversive beyond some maximal Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed sweet-responsive gustatory receptor neurons (GRNs) in labellum, a peripheral organ, mediate feeding behaviors toward dilute acids. Here, we disclose existence pharyngeal sensors melanogaster detect ingested also involved responses These rely IR51b, IR94a, IR94h, together with IR76b, drive We then demonstrate optogenetic activation either Ir94a + or Ir94h GRNs promotes an response, confirming their contributions behavior. Our discovery internal sour taste opens up new avenues for investigating sensation tastants insects.

Language: Английский

Harnessing Insect Chemosensory and Mechanosensory Receptors Involved in Feeding for Precision Pest Management DOI Creative Commons
Ting‐Wei Mi,

Cheng‐Wang Sheng,

C. Lee

et al.

Life, Journal Year: 2025, Volume and Issue: 15(1), P. 110 - 110

Published: Jan. 16, 2025

Chemosensation and mechanosensation are vital to insects’ survival behavior, shaping critical physiological processes such as feeding, metabolism, mating, reproduction. During insects rely on diverse chemosensory mechanosensory receptors distinguish between nutritious harmful substances, enabling them select suitable food sources while avoiding toxins. These distributed across various body parts, allowing detect environmental cues about quality adjust their behaviors accordingly. A deeper understanding of insect sensory physiology, especially during not only enhances our knowledge biology but also offers significant opportunities for practical applications. This review highlights recent advancements in research feeding-related receptors, covering a wide range species, from the model organism Drosophila melanogaster agricultural human pests. Additionally, this examines potential targeting precision pest control. Disrupting feeding reproduction emerges promising strategy management. By interfering with these essential behaviors, we can effectively control populations minimizing impacts promoting ecological balance.

Language: Английский

Citations

0
Taste Detection of Flonicamid in Drosophila melanogaster DOI
Muhammad Atif, Youngseok Lee

Insect Biochemistry and Molecular Biology, Journal Year: 2025, Volume and Issue: unknown, P. 104302 - 104302

Published: March 1, 2025

Language: Английский

Citations

0
Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster DOI Creative Commons

Bhanu Shrestha,

Jiun Sang, Suman Rimal

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Oct. 2, 2024

Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied date, the attractiveness of oral acids contingent on concentration. Many carboxylic are attractive at ecologically relevant concentrations but become aversive beyond some maximal Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed sweet-responsive gustatory receptor neurons (GRNs) in labellum, a peripheral organ, mediate feeding behaviors toward dilute acids. Here, we disclose existence pharyngeal sensors melanogaster detect ingested also involved responses These rely IR51b, IR94a, IR94h, together with IR76b, drive We then demonstrate optogenetic activation either Ir94a + or Ir94h GRNs promotes an response, confirming their contributions behavior. Our discovery internal sour taste opens up new avenues for investigating sensation tastants insects.

Language: Английский

Citations

2
Age-dependent switched taste behavior to ribose DOI
Jiun Sang, Youngseok Lee

Insect Biochemistry and Molecular Biology, Journal Year: 2024, Volume and Issue: 174, P. 104194 - 104194

Published: Oct. 13, 2024

Language: Английский

Citations

2
Pharyngeal neuronal mechanisms governing sour taste perception inDrosophila melanogaster DOI Creative Commons
Bhanu Shrestha, Jiun Sang, Suman Rimal

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 30, 2024

Abstract Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied date, the attractiveness of oral acids contingent on concentration. Many carboxylic are attractive at ecologically relevant concentrations but become aversive beyond some maximal Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed sweet-responsive gustatory receptor neurons (GRNs) in labellum, a peripheral organ, mediate feeding behaviors toward dilute acids. Here, we disclose existence pharyngeal sensors D. melanogaster detect ingested also involved responses These rely IR51b, IR94a, IR94h, together with IR76b, drive We then demonstrate optogenetic activation either Ir94a + or Ir94h GRNs promotes an response, confirming their contributions behavior. Our discovery internal sour taste opens up new avenues for investigating sensation tastants insects.

Language: Английский

Citations

0
Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster DOI Open Access

Bhanu Shrestha,

Jiun Sang, Suman Rimal

et al.

Published: Oct. 2, 2024

Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied date, the attractiveness of oral acids contingent on concentration. Many carboxylic are attractive at ecologically relevant concentrations but become aversive beyond some maximal Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed sweet-responsive gustatory receptor neurons (GRNs) in labellum, a peripheral organ, mediate feeding behaviors toward dilute acids. Here, we disclose existence pharyngeal sensors D. melanogaster detect ingested also involved responses These rely IR51b, IR94a, IR94h, together with IR76b, drive We then demonstrate optogenetic activation either Ir94a + or Ir94h GRNs promotes an response, confirming their contributions behavior. Our discovery internal sour taste opens up new avenues for investigating sensation tastants insects.

Language: Английский

Citations

0
Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster DOI Creative Commons
Bhanu Shrestha, Jiun Sang, Suman Rimal

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Dec. 11, 2024

Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied date, the attractiveness of oral acids contingent on concentration. Many carboxylic are attractive at ecologically relevant concentrations but become aversive beyond some maximal Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed sweet-responsive gustatory receptor neurons (GRNs) in labellum, a peripheral organ, mediate feeding behaviors toward dilute acids. Here, we disclose existence pharyngeal sensors melanogaster detect ingested also involved responses These rely IR51b, IR94a, IR94h, together with IR76b, drive We then demonstrate optogenetic activation either Ir94a + or Ir94h GRNs promotes an response, confirming their contributions behavior. Our discovery internal sour taste opens up new avenues for investigating sensation tastants insects.

Language: Английский

Citations

0