Anti-Inflammatory Effects of Novel Probiotic Lactobacillus rhamnosus RL-H3-005 and Pedicoccus acidilactici RP-H3-006: In Vivo and In Vitro Evidence DOI Creative Commons
Shugang Li, Yixuan Li,

Donglin Sui

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(22), P. 3676 - 3676

Published: Nov. 18, 2024

Probiotics have garnered escalating attention in the treatment and prevention of inflammatory disorders. In this study,

Language: Английский

Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants DOI Creative Commons
Wen Sun, Lin Tao, Chen Qian

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2025, Volume and Issue: 14

Published: Jan. 6, 2025

Breast milk is an essential source of infant nutrition. It also a vital determinant the structure and function intestinal microbial community, it connects mother microbiota. Human oligosaccharides (HMOs) are critical component in breast milk. HMOs can reach baby's colon entirely from become fermentable substrate for some microorganisms. enhance mucosal barrier affect host through immune function, which has therapeutic effect on specific diseases, such as necrotizing enterocolitis. In addition, changes microbiota reflect maternal link between infants related to Through breastfeeding, jointly bacteria. Therefore, positively influence establishment balance ensure function. be used supplement alternative therapy diseases.

Language: Английский

Citations

1
Anti-Inflammatory and Antidiarrheal Effects of Two Strains of Lactic Acid Bacteria Isolated from Healthy Pets on Escherichia coli K88-Induced Diarrhea in Mice DOI Creative Commons

Ya Zhao,

Shukun Liang,

Xiaoxin Fu

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(2), P. 239 - 239

Published: Jan. 22, 2025

Lactic acid bacteria play a crucial role in maintaining the health of host’s gut microbiota. In this study, anti-inflammatory properties Limosilactobacillus reuteri LR20-6 and Lacticplantibacillus plantarum L272 were evaluated using mouse model diarrhea induced by Escherichia coli. We also investigated their effects on microbiota regulation. The results indicated that both could reduce inflammation inhibiting expression inflammatory factors IL-6 TNF-α blocking MyD88 NF-kB/p65 signaling pathways. Additionally, after intervention with these strains, relative abundance Lactobacillus was significantly increased. This suggested mitigate severity E. coli-induced enhance beneficial probiotics animals.

Language: Английский

Citations

0
Engineered Probiotic-Based Biomaterials for Inflammatory Bowel Disease Treatment DOI Creative Commons

Guangze Sang,

Bo Wang, Yujie Xie

et al.

Theranostics, Journal Year: 2025, Volume and Issue: 15(8), P. 3289 - 3315

Published: Feb. 18, 2025

Inflammatory bowel disease (IBD) is a chronic condition affecting the intestines, marked by immune-mediated inflammation. This known for its recurrent nature and challenges it presents in treatment. Recently, probiotic have gained attention as promising alternative to traditional small molecular drugs monoclonal antibody chemotherapies IBD. Probiotic, recognized "living" therapeutic agent, offers targeted treatment with minimal side effects flexibility biological modifications, making them highly effective IBD management. comprehensive review latest advancements engineering probiotic-based materials, ranging from basic mechanisms modification techniques used It delves deep into how produces intestinal environment discusses various strategies enhance probiotic's efficacy, including genetic modifications formulation improvements. Additionally, addresses challenges, practical application conditions, future research directions of therapies treatment, providing insights their feasibility potential clinical implications.

Language: Английский

Citations

0
Effects of the Welfare Housing Systems Based on Environmental Enrichment on Growth Performance, Meat Quality, and Intestinal Health in Rabbits DOI
Zhitong Wang, Ran Zhang,

Guanchen Du

et al.

The FASEB Journal, Journal Year: 2025, Volume and Issue: 39(10)

Published: May 19, 2025

ABSTRACT In recent years, consumers have shown a growing interest in purchasing welfare‐friendly livestock products. Environmental enrichment has emerged as an effective approach to enhancing animal welfare. Based on this, this study aims investigate the effects of welfare housing systems incorporating environmental growth performance, meat quality, and intestinal health rabbits. Rabbits were assigned into three groups: Cage group (Cage), Pen (Pen), + material (PE). The exhibited lower average daily weight gain higher feed conversion ratio. However, color nutrient content leg muscles improved both PE groups varying extents. Furthermore, fatty acid β‐oxidation was elevated group, resulting reduced lipid deposition. Additionally, displayed altered cecal microbiota composition increased short‐chain acids content, contributing enhanced through activation G protein‐coupled receptors. conclusion, these findings suggest that two can improve quality health. This offers theoretical foundation for welfare‐oriented rabbit farming production healthier meet consumer demands.

Language: Английский

Citations

0
Anti-Inflammatory Effects of Novel Probiotic Lactobacillus rhamnosus RL-H3-005 and Pedicoccus acidilactici RP-H3-006: In Vivo and In Vitro Evidence DOI Creative Commons
Shugang Li, Yixuan Li,

Donglin Sui

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(22), P. 3676 - 3676

Published: Nov. 18, 2024

Probiotics have garnered escalating attention in the treatment and prevention of inflammatory disorders. In this study,

Language: Английский

Citations

0