How an Anode‐Sided Gap Influences the Electrooxidation of Phenols in Flow Reactors DOI Creative Commons
Jonas Wolf,

Nijiati Yasheng,

Julian T. Kleinhaus

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Abstract Electroorganic synthesis offers a sustainable way to valorize chemical building blocks through renewable energy and environmentally friendly reagents. Substituted quinones, vital for manufacturing supplements, pharmaceuticals, pesticides, are typically derived from phenols via thermochemical oxidation with inorganic oxidizers specialized catalysts. Electrochemistry's ability omit such components highlights the appeal of electrifying this process. This study explores electrochemical 2,3,5‐trimethylphenol (TMP) into trimethyl‐1,4‐benzoquinone (TMQ) – crucial intermediate vitamin E production using zero‐gap electrolyzer. A TMQ yield 18 % selectivity 22 were achieved, improving 35 37 %, respectively, an anode‐sided spacer. We sought identify factors promoting formation in reactors gap, addressing limitations configurations investigating dependency on half‐cell potential, local reactant concentrations, pH, electrolyte convection. The results revealed that substrate concentration is interrelated convection most critical factor responsible gap‐related effect. 33 32 achieved continuous flow conditions electrolyzer at optimized conditions. These findings underscore role concentrations scaling synthetic reactions, providing robust framework tackling future challenges field.

Language: Английский

How an Anode‐Sided Gap Influences the Electrooxidation of Phenols in Flow Reactors DOI Creative Commons
Jonas Wolf,

Nijiati Yasheng,

Julian T. Kleinhaus

et al.

ChemElectroChem, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Abstract Electroorganic synthesis offers a sustainable way to valorize chemical building blocks through renewable energy and environmentally friendly reagents. Substituted quinones, vital for manufacturing supplements, pharmaceuticals, pesticides, are typically derived from phenols via thermochemical oxidation with inorganic oxidizers specialized catalysts. Electrochemistry's ability omit such components highlights the appeal of electrifying this process. This study explores electrochemical 2,3,5‐trimethylphenol (TMP) into trimethyl‐1,4‐benzoquinone (TMQ) – crucial intermediate vitamin E production using zero‐gap electrolyzer. A TMQ yield 18 % selectivity 22 were achieved, improving 35 37 %, respectively, an anode‐sided spacer. We sought identify factors promoting formation in reactors gap, addressing limitations configurations investigating dependency on half‐cell potential, local reactant concentrations, pH, electrolyte convection. The results revealed that substrate concentration is interrelated convection most critical factor responsible gap‐related effect. 33 32 achieved continuous flow conditions electrolyzer at optimized conditions. These findings underscore role concentrations scaling synthetic reactions, providing robust framework tackling future challenges field.

Language: Английский

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