Efficacy and safety of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with acute heart failure: a systematic review and meta-analysis DOI Creative Commons

Jingjin Hou,

Li Ren,

Qingbin Hou

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 11, 2024

The effectiveness and safety of a novel class hypoglycemic medications known as sodium-glucose cotransporter 2 (SGLT2) inhibitors have not been completely established in relation to acute heart failure (AHF). Consequently, we sought compare the prognostic outcomes patients administered SGLT2 for treatment AHF.

Language: Английский

Inferior vena CAVA and lung ultraSound-guided therapy in acute heart failure: A randomized pilot study (CAVAL US-AHF study) DOI
Lucrecia María Burgos,

Rocío Consuelo Baro Vila,

F Ballari

et al.

American Heart Journal, Journal Year: 2024, Volume and Issue: 277, P. 47 - 57

Published: July 31, 2024

Language: Английский

Citations

3

Rationale and Design of the Dapagliflozin Effect on Cardiovascular Events in Acute Heart Failure (DAPA ACT HF)-TIMI 68 Trial DOI
David D. Berg, Siddharth Patel, Paul M. Haller

et al.

JACC Heart Failure, Journal Year: 2025, Volume and Issue: 13(5), P. 829 - 839

Published: May 1, 2025

Language: Английский

Citations

0

Diuretic Treatment in Heart Failure: A Practical Guide for Clinicians DOI Open Access
Lingling Wu, Mario Rodríguez, Karim El Hachem

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(15), P. 4470 - 4470

Published: July 30, 2024

Congestion and fluid retention are the hallmarks of decompensated heart failure major reason for hospitalization patients with failure. Diuretics have been used in decades, they remain backbone contemporary management Loop diuretics is preferred diuretic, it has given a class I recommendation by clinical guidelines relief congestion symptoms. Although loop virtually among all acute failure, there still very limited evidence to guide optimized use. This sharp contrast rapidly growing rest guideline-directed medical therapy calls further studies. The possess unique pharmacology pharmacokinetics that lay ground different strategies increase diuretic efficiency. However, many these approaches not evaluated randomized trials. In recent years, stepped protocolized dosing suggested superior benefits over an individual clinician-based strategy. Diuretic resistance challenge decongestion associated poor prognosis. Recently, options emerged help overcome this review, we aim provide comprehensive review use context attention its side effects, adjuncts, as well challenges future direction.

Language: Английский

Citations

2

The utility of urine sodium–guided diuresis during acute decompensated heart failure DOI Creative Commons
Hasan K. Siddiqi, Zachary L. Cox, Lynne W. Stevenson

et al.

Heart Failure Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 12, 2024

Abstract Diuresis to achieve decongestion is a central aim of therapy in patients hospitalized for acute decompensated heart failure (ADHF). While multiple approaches have been tried adequate rapidly while minimizing adverse effects, no single diuretic strategy has shown superiority, and there paucity data guidelines utilize making these decisions. Observational cohort studies associations between urine sodium excretion outcomes after hospitalization ADHF. Urine chemistries (urine ± creatinine) may guide titration during ADHF, randomized clinical trials designed compare chemistry–guided diuresis usual care. This review will summarize current literature monitoring strategies, outline evidence gaps, describe the recently completed ongoing address gaps with ADHF particular focus on utility sodium–guided strategies.

Language: Английский

Citations

2

Efficacy and safety of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with acute heart failure: a systematic review and meta-analysis DOI Creative Commons

Jingjin Hou,

Li Ren,

Qingbin Hou

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 11, 2024

The effectiveness and safety of a novel class hypoglycemic medications known as sodium-glucose cotransporter 2 (SGLT2) inhibitors have not been completely established in relation to acute heart failure (AHF). Consequently, we sought compare the prognostic outcomes patients administered SGLT2 for treatment AHF.

Language: Английский

Citations

2