Frontiers in Cardiovascular Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Sept. 11, 2024
The
effectiveness
and
safety
of
a
novel
class
hypoglycemic
medications
known
as
sodium-glucose
cotransporter
2
(SGLT2)
inhibitors
have
not
been
completely
established
in
relation
to
acute
heart
failure
(AHF).
Consequently,
we
sought
compare
the
prognostic
outcomes
patients
administered
SGLT2
for
treatment
AHF.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(15), P. 4470 - 4470
Published: July 30, 2024
Congestion
and
fluid
retention
are
the
hallmarks
of
decompensated
heart
failure
major
reason
for
hospitalization
patients
with
failure.
Diuretics
have
been
used
in
decades,
they
remain
backbone
contemporary
management
Loop
diuretics
is
preferred
diuretic,
it
has
given
a
class
I
recommendation
by
clinical
guidelines
relief
congestion
symptoms.
Although
loop
virtually
among
all
acute
failure,
there
still
very
limited
evidence
to
guide
optimized
use.
This
sharp
contrast
rapidly
growing
rest
guideline-directed
medical
therapy
calls
further
studies.
The
possess
unique
pharmacology
pharmacokinetics
that
lay
ground
different
strategies
increase
diuretic
efficiency.
However,
many
these
approaches
not
evaluated
randomized
trials.
In
recent
years,
stepped
protocolized
dosing
suggested
superior
benefits
over
an
individual
clinician-based
strategy.
Diuretic
resistance
challenge
decongestion
associated
poor
prognosis.
Recently,
options
emerged
help
overcome
this
review,
we
aim
provide
comprehensive
review
use
context
attention
its
side
effects,
adjuncts,
as
well
challenges
future
direction.
Heart Failure Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 12, 2024
Abstract
Diuresis
to
achieve
decongestion
is
a
central
aim
of
therapy
in
patients
hospitalized
for
acute
decompensated
heart
failure
(ADHF).
While
multiple
approaches
have
been
tried
adequate
rapidly
while
minimizing
adverse
effects,
no
single
diuretic
strategy
has
shown
superiority,
and
there
paucity
data
guidelines
utilize
making
these
decisions.
Observational
cohort
studies
associations
between
urine
sodium
excretion
outcomes
after
hospitalization
ADHF.
Urine
chemistries
(urine
±
creatinine)
may
guide
titration
during
ADHF,
randomized
clinical
trials
designed
compare
chemistry–guided
diuresis
usual
care.
This
review
will
summarize
current
literature
monitoring
strategies,
outline
evidence
gaps,
describe
the
recently
completed
ongoing
address
gaps
with
ADHF
particular
focus
on
utility
sodium–guided
strategies.
Frontiers in Cardiovascular Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Sept. 11, 2024
The
effectiveness
and
safety
of
a
novel
class
hypoglycemic
medications
known
as
sodium-glucose
cotransporter
2
(SGLT2)
inhibitors
have
not
been
completely
established
in
relation
to
acute
heart
failure
(AHF).
Consequently,
we
sought
compare
the
prognostic
outcomes
patients
administered
SGLT2
for
treatment
AHF.