European Heart Journal - Cardiovascular Imaging,
Journal Year:
2024,
Volume and Issue:
25(10), P. e250 - e250
Published: Aug. 17, 2024
Journal
Article
Accepted
manuscript
Education
and
Information
to
Reduce
Aortic
Aneurysm
Mortality
Rates
Get
access
Michael
Huy
Cuong
Pham,
MD,
MD
Department
of
Cardiology,
The
Heart
Center,
Copenhagen
University
Hospital
-
Rigshospitalet,
Copenhagen,
DenmarkDepartment
Radiology,
Diagnostic
Denmark
Address
for
correspondence:
Cardiology
&
2014,
Rigshospitalet
Clinical
Medicine,
Faculty
Health
Medical
Sciences,
Blegdamsvej
9,
2100-CPH,
Denmark,
E-mail:
[email protected],
Phone:
+45
60590202
Mobile:
https://orcid.org/0000-0002-6577-0079
Search
other
works
by
this
author
on:
Oxford
Academic
PubMed
Google
Scholar
Shoaib
Afzal,
PhD,
DMSc,
DMSc
https://orcid.org/0000-0002-1442-4694
Klaus
Fuglsang
Kofoed,
https://orcid.org/0000-0001-9742-1554
European
Cardiovascular
Imaging,
jeae208,
https://doi.org/10.1093/ehjci/jeae208
Published:
17
August
2024
history
Received:
24
July
Accepted:
09
Journal of Cardiovascular Development and Disease,
Journal Year:
2024,
Volume and Issue:
11(8), P. 245 - 245
Published: Aug. 9, 2024
Cardiovascular
diseases
(CVDs)
remain
a
major
global
health
challenge,
leading
to
significant
morbidity
and
mortality
while
straining
healthcare
systems.
Despite
progress
in
medical
treatments
for
CVDs,
their
increasing
prevalence
calls
shift
towards
more
effective
prevention
strategies.
Traditional
preventive
approaches
have
centered
around
lifestyle
changes,
risk
factors
management,
medication.
However,
the
integration
of
imaging
methods
offers
novel
dimension
early
disease
detection,
assessment,
ongoing
monitoring
at-risk
individuals.
Imaging
techniques
such
as
supra-aortic
trunks
ultrasound,
echocardiography,
cardiac
magnetic
resonance,
coronary
computed
tomography
angiography
broadened
our
understanding
anatomical
functional
aspects
cardiovascular
health.
These
enable
personalized
strategies
by
providing
detailed
insights
into
vascular
states,
significantly
enhancing
ability
combat
progression
CVDs.
This
review
focuses
on
amalgamating
current
findings,
technological
innovations,
impact
integrating
advanced
modalities
prevention,
aiming
offer
comprehensive
perspective
potential
transform
cardiology.
Current Opinion in Lipidology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 23, 2025
Purpose
of
review
For
many
years,
inflammation
has
been
a
major
concept
in
basic
research
on
atherosclerosis
and
the
development
potential
diagnostic
tools
treatments.
The
purpose
this
is
to
assess
performance
with
an
emphasis
recent
clinical
trials.
In
addition,
contemporary
literature
may
help
identify
new
therapeutic
targets,
particularly
context
treatment
early,
rather
than
end-stage,
arterial
disease.
Recent
findings
Newly
reported
trials
cast
doubt
efficacy
colchicine,
sole
anti-inflammatory
agent
currently
approved
for
use
patients
atherosclerotic
cardiovascular
disease
(ASCVD).
New
analyses
also
challenge
hypothesis
that
residual
ASCVD
event
risk
after
optimal
management
lipids,
blood
pressure,
smoking
arises
primarily
from
inflammatory
risk.
Current
practice
initiate
interventions
so
late
course
be
better
explanation.
Lipid-lowering
therapy
early
atherosclerosis,
possibly
combined
novel
add-on
agents
specifically
accelerate
resolution
maladaptive
inflammation,
more
fruitful
conventional
approach
testing
immunosuppressive
strategies
end-stage
Also
discussed
ongoing
revolution
noninvasive
technologies
image
wall.
These
are
changing
screening,
diagnosis,
including
reversable
Summary
burden
proof
Big
Idea
value
remains
responsibility
its
advocates.
This
requires
convincing
trial
data
but
still
seems
largely
unmet.
Unfortunately,
focus
as
source
distracted
us
need
screen
treat
earlier.
Singapore Medical Journal,
Journal Year:
2025,
Volume and Issue:
66(3), P. 141 - 146
Published: March 1, 2025
Subclinical
atherosclerosis
underlies
most
cardiovascular
diseases,
manifesting
before
clinical
symptoms
and
representing
a
key
focus
for
early
prevention
strategies.
Recent
advancements
highlight
the
importance
of
detection
management
subclinical
atherosclerosis.
This
review
underscores
that
traditional
risk
factor
levels
considered
safe,
such
as
low-density
lipoprotein
cholesterol
(LDL-C)
glycated
haemoglobin
(HbA1c),
may
still
permit
development
atherosclerosis,
suggesting
need
stricter
thresholds.
Early-life
interventions
are
crucial,
leveraging
brain's
neuroplasticity
to
establish
lifelong
healthy
habits.
Preventive
strategies
should
include
more
aggressive
LDL-C
HbA1c
from
youth
persist
into
old
age,
supported
by
public
health
policies
promote
environments.
Emphasising
education
on
can
fundamentally
shift
trajectory
disease
optimise
long-term
outcomes.
npj Science of Food,
Journal Year:
2025,
Volume and Issue:
9(1)
Published: Jan. 13, 2025
Atherosclerosis
is
a
primary
cause
of
cardiovascular
disease,
straining
healthcare
systems.
Dendrobium
officinale,
widely
used
food-medicine
homology,
has
demonstrated
anti-atherosclerotic
(anti-AS)
properties,
with
other
species
listed
in
pharmacopoeias
exhibiting
similar
effects.
However,
their
efficacy
varies,
and
the
impact
interspecies
variations
on
compounds
mechanisms
Dendrobium's
anti-AS
effects
remains
unclear.
This
study
aimed
to
explore
across
various
species.
The
chemical
composition
D.
fimbriatum,
devonianum,
gratiosissimum,
catenatum
was
analyzed
using
UPLC-Q-Exactive
Orbitrap
MS.
Network
pharmacology
predicted
pharmacological
basis
molecular
mechanisms.
Molecular
docking
experiments
assessed
binding
affinity
identified
target
proteins.
A
total
12
different
65
common
components
were
identified.
Key
therapeutic
targets
included
SRC,
STAT3,
PIK3CA,
along
relevant
signaling
pathways
linked
AS
prevention.
provides
insights
into
differences
properties.
