Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 191, P. 114887 - 114887
Published: Sept. 1, 2024
Language: Английский
Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 191, P. 114887 - 114887
Published: Sept. 1, 2024
Language: Английский
Cytokine & Growth Factor Reviews, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0Communications Biology, Journal Year: 2025, Volume and Issue: 8(1)
Published: April 26, 2025
Language: Английский
Citations
0World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(5)
Published: April 30, 2025
Schizophrenia is a complex neuropsychiatric disorder characterized by cognitive, emotional, and behavioral impairments. The microbiota-gut-brain axis crucial in its pathophysiology, mediating communication between the gut brain through neural, immune, endocrine, metabolic pathways. Dysbiosis, or an imbalance microbiota, linked to neuroinflammation, systemic inflammation, neurotransmitter disruptions, all of which contribute symptoms schizophrenia. Gut microbiota-derived metabolites, such as short-chain fatty acids, influence function, including immune responses synthesis. These findings suggest that microbial imbalances exacerbate schizophrenia, providing novel perspective on disorder’s underlying mechanisms. Emerging microbiota-targeted therapies—such probiotics, prebiotics, dietary interventions, fecal microbiota transplantation—show promise adjunctive treatments, aiming restore balance improve clinical outcomes. While further research needed, targeting offers innovative approach schizophrenia management, with potential enhance patient outcomes quality life.
Language: Английский
Citations
0Applied Microbiology and Biotechnology, Journal Year: 2023, Volume and Issue: 107(22), P. 6737 - 6749
Published: Sept. 22, 2023
Language: Английский
Citations
9Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 191, P. 114887 - 114887
Published: Sept. 1, 2024
Language: Английский
Citations
3