NSAID Allergy Labels Associated With Mortality and Cardiovascular Outcomes in Stroke DOI
Clara Tsui, Hugo W.F. Mak, William Leung

et al.

Stroke, Journal Year: 2024, Volume and Issue: 56(1), P. 30 - 38

Published: Nov. 19, 2024

BACKGROUND: Mislabeled drug allergy can restrict future prescriptions and medication use, but its prevalence impact among patients with stroke remain unknown. This study investigated the of most commonly labeled allergies, their accuracy, stroke. METHODS: In this combined longitudinal cross-sectional study, we compared labels general population ischemic between 2008 2014 from electronic health care records in Hong Kong. Outcomes or without prevalent (ie, NSAID) were compared. Rate mislabeled NSAID was confirmed by provocation testing. RESULTS: Compared (n=702 966), had more (n=235) to cardiovascular hematopoietic system (prevalence, 19.5% versus 9.2%; odds ratio [OR], 2.4 [95% CI, 1.74–3.32]; P <0.001) radiographic diagnostic agents 4.2% 0.9%; OR, 4.82 2.56–9.08]; <0.001). The common 1.8%). Patients significantly less likely be prescribed aspirin after acute (OR, 0.24 0.09–0.60]; =0.003) on follow-up 0.22 0.08–0.56]; =0.002). median duration 6.7 years (6499±2.49 patient-years). also experienced higher mortality 7.44 2.44–23.18]; <0.001), peripheral vascular disease 9.35 1.95–44.86]; =0.005), major adverse events 6.09 2.00–18.58]; =0.001) poststroke period. (who remained alive could consent) referred for allergist assessment offered majority (80%; 4/5) negative tests delabeled. CONCLUSIONS: stroke, associated excessive mortality, disease, events. Given high rate multidisciplinary neuro-allergy interventions have potential improve patient outcomes.

Language: Английский

Global productivity, international collaborations, and research trends in chronic spontaneous urticaria: A bibliometric overview DOI Creative Commons
Hugo W.F. Mak, Freya K L Chung, Philip H. Li

et al.

Journal of Allergy and Clinical Immunology Global, Journal Year: 2025, Volume and Issue: unknown, P. 100455 - 100455

Published: March 1, 2025

Language: Английский

Citations

0
NSAID Allergy Labels Associated With Mortality and Cardiovascular Outcomes in Stroke DOI
Clara Tsui, Hugo W.F. Mak, William Leung

et al.

Stroke, Journal Year: 2024, Volume and Issue: 56(1), P. 30 - 38

Published: Nov. 19, 2024

BACKGROUND: Mislabeled drug allergy can restrict future prescriptions and medication use, but its prevalence impact among patients with stroke remain unknown. This study investigated the of most commonly labeled allergies, their accuracy, stroke. METHODS: In this combined longitudinal cross-sectional study, we compared labels general population ischemic between 2008 2014 from electronic health care records in Hong Kong. Outcomes or without prevalent (ie, NSAID) were compared. Rate mislabeled NSAID was confirmed by provocation testing. RESULTS: Compared (n=702 966), had more (n=235) to cardiovascular hematopoietic system (prevalence, 19.5% versus 9.2%; odds ratio [OR], 2.4 [95% CI, 1.74–3.32]; P <0.001) radiographic diagnostic agents 4.2% 0.9%; OR, 4.82 2.56–9.08]; <0.001). The common 1.8%). Patients significantly less likely be prescribed aspirin after acute (OR, 0.24 0.09–0.60]; =0.003) on follow-up 0.22 0.08–0.56]; =0.002). median duration 6.7 years (6499±2.49 patient-years). also experienced higher mortality 7.44 2.44–23.18]; <0.001), peripheral vascular disease 9.35 1.95–44.86]; =0.005), major adverse events 6.09 2.00–18.58]; =0.001) poststroke period. (who remained alive could consent) referred for allergist assessment offered majority (80%; 4/5) negative tests delabeled. CONCLUSIONS: stroke, associated excessive mortality, disease, events. Given high rate multidisciplinary neuro-allergy interventions have potential improve patient outcomes.

Language: Английский

Citations

2