PEDIATRICS,
Journal Year:
2017,
Volume and Issue:
139(Supplement_1), P. S38 - S49
Published: March 31, 2017
The
rapid
pace
of
fetal
development
by
far
exceeds
any
other
stage
the
life
span,
and
thus,
environmental
influences
can
profoundly
alter
developmental
course.
Stress
during
prenatal
period,
including
malnutrition
inflammation,
impact
maternal
neurodevelopment
with
long-term
consequences
for
physical
mental
health
both
mother
her
child.
One
primary
consequence
malnutrition,
sources
stress
is
a
poor
birth
outcome,
such
as
prematurity
or
growth
restriction.
These
phenotypes
are
often
used
indications
adversity.
In
fact,
original
evidence
supporting
programming
hypothesis
came
from
studies
documenting
an
association
between
phenotype
subsequent
problems.
Fetal
restriction
in
term
preterm
infants
associated
neonatal
morbidities
wide
variety
behavioral
psychological
diagnoses
childhood
adolescence,
attention-deficit/hyperactivity
disorder,
anxiety,
depression,
internalizing
thought
problems,
social
skills,
autism
spectrum
disorder.
Improving
maternal-child
requires
interventions
that
begin
before
pregnancy
continue
throughout
gestation
into
postpartum
period.
Such
might
include
intention,
nutrition,
health/medical
care,
health,
providing
support.
This
article
discusses
nutrition
inflammation
preconception
among
women
living
low-resource
settings,
emphasis
on
key
knowledge
gaps
need
to
be
addressed
guide
program
policy
decisions
at
local,
regional
global
levels.
Frontiers in Psychiatry,
Journal Year:
2023,
Volume and Issue:
13
Published: Jan. 4, 2023
Objective
To
observe
and
evaluate
the
effect
of
a
single
intravenous
injection
low-dose
esketamine
on
post-operative
pain
post-partum
depression
(PPD)
in
cesarean
delivery
patients.
Methods
A
total
210
patients
undergoing
elective
under
combined
spinal-epidural
anesthesia
were
divided
into
an
group
(Group
S,
n
=
105)
normal
saline
L,
by
random
number
table.
At
5
min
after
childbirth,
S
given
0.25
mg/kg
esketamine,
whereas
L
received
equal
volume
saline.
The
primary
outcomes
included
control
according
to
Numerical
Rating
Scale
(NRS)
incidence
PPD
Edinburgh
Post-partum
Depression
(EPDS).
secondary
analgesia-related
adverse
events
Ramsay
sedation
scores.
Results
This
clinical
study
was
prospective,
randomized,
double-blind
trial.
enrolled
this
study.
NRS
(cough
pain)
score
lower
than
at
24
h
surgery
(
P
0.016),
there
no
significant
difference
resting
mobilization
4,
8,
48
or
between
two
groups.
There
prevalence
groups
day
before
delivery,
first
week,
second
fourth
week
childbirth.
dosing,
hallucinations
<
0.001)
dizziness
higher
group.
15
nausea
0.011)
when
leaving
operating
room.
scores
Group
p
0.001),
dosing
time
room
0.001).
Conclusion
In
study,
did
not
reduce
1,
2,
4
w
but
improved
during
exercise
post-operatively
conditions
Clinical
trial
registration
[
www.chictr.org.cn
],
identifier
[ChiCTR2100054332].
Psychological Medicine,
Journal Year:
2017,
Volume and Issue:
48(7), P. 1190 - 1200
Published: Sept. 27, 2017
Abstract
Background
Race,
psychiatric
history,
and
adverse
life
events
have
all
been
independently
associated
with
postpartum
depression
(PPD).
However,
the
role
these
play
together
in
Black
Latina
women
remains
inadequately
studied.
Therefore,
we
performed
a
case–control
study
of
PPD,
including
comprehensive
assessments
symptoms
biomarkers,
while
examining
effects
genetic
ancestry.
Methods
We
recruited
our
sample
(549
cases,
968
controls)
at
6
weeks
from
obstetrical
clinics
North
Carolina.
PPD
status
was
determined
using
MINI-plus.
Psychiatric
history
extracted
medical
records.
Participants
were
administered
self-report
instruments
to
assess
(Edinburgh
Postnatal
Depression
Scale)
events.
Levels
estradiol,
progesterone,
brain-derived
neurotrophic
factor,
oxytocin,
allopregnanalone
assayed.
Principal
components
genotype
data
used
estimate
ancestry
logistic
regression
identify
predictors
PPD.
Results
This
population
racially
diverse
(68%
Black,
13%
Latina,
18%
European).
Genetic
not
predictor
Case
predicted
by
major
(
p
=
4.01E-14),
lifetime
anxiety
disorder
diagnosis
1.25E-34),
6.06E-06).
There
no
significant
differences
between
groups
any
hormones
or
neurosteroids.
Conclusions
multiple
exposures
minority
low-income
women.
hormone
levels
predictive
case
status.
Increased
vulnerability
conjunction
risk
factors
may
predict
onset
whereas
does
appear
predictive.
PEDIATRICS,
Journal Year:
2017,
Volume and Issue:
139(Supplement_1), P. S38 - S49
Published: March 31, 2017
The
rapid
pace
of
fetal
development
by
far
exceeds
any
other
stage
the
life
span,
and
thus,
environmental
influences
can
profoundly
alter
developmental
course.
Stress
during
prenatal
period,
including
malnutrition
inflammation,
impact
maternal
neurodevelopment
with
long-term
consequences
for
physical
mental
health
both
mother
her
child.
One
primary
consequence
malnutrition,
sources
stress
is
a
poor
birth
outcome,
such
as
prematurity
or
growth
restriction.
These
phenotypes
are
often
used
indications
adversity.
In
fact,
original
evidence
supporting
programming
hypothesis
came
from
studies
documenting
an
association
between
phenotype
subsequent
problems.
Fetal
restriction
in
term
preterm
infants
associated
neonatal
morbidities
wide
variety
behavioral
psychological
diagnoses
childhood
adolescence,
attention-deficit/hyperactivity
disorder,
anxiety,
depression,
internalizing
thought
problems,
social
skills,
autism
spectrum
disorder.
Improving
maternal-child
requires
interventions
that
begin
before
pregnancy
continue
throughout
gestation
into
postpartum
period.
Such
might
include
intention,
nutrition,
health/medical
care,
health,
providing
support.
This
article
discusses
nutrition
inflammation
preconception
among
women
living
low-resource
settings,
emphasis
on
key
knowledge
gaps
need
to
be
addressed
guide
program
policy
decisions
at
local,
regional
global
levels.
