Prevalence and variables associated with depression, anxiety, and stress among Chilean higher education students, post-pandemic

Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14

Published: March 30, 2023

Mental health among university students is a public problem in Chile, understanding that this population susceptible to mental disorders.The present study aimed determine the prevalence and variables influencing depression, anxiety, stress Chilean students.A representative sample (n = 1,062) of cross-sectional design were used. Bivariate analysis multiple logistic regression performed identify risk factors associated with symptomatology. They analyzed using descriptive statistics. A questionnaire sociodemographic was applied November 2022, addition depression anxiety scale (DASS-21), instruments excellent reliability (α 0.955; ω 0.956). On other hand, Questionnaire Problematic Alcohol Drug Consumption (DEP-ADO) applied. performed, followed by bivariate SPSS version 25. The showed value p <0.05; they declared statistically significant final model. Odds ratios (OR) adjusted 95% confidence interval (95% CI), which used independent predictors.The problems high, depressive symptoms 63.1% sample; 69.2% anxiety; 57% stress; 27.4% problematic alcohol consumption; 14.9% inappropriate marijuana consumption. Some 10.1% reported daily medication antidepressants and/or anxiolytics. Concerning for these were: being female, belonging sexual, not having children, use, prescription drugs. woman, sexual minorities, an adolescent, consuming medication. Finally, concerning stress, student dedicated exclusively academic activities, taking medication.Chilean presented high where female minorities seem be have greatest impact on susceptibility problems. These results should call attention political authorities Chile improve population's quality life since are following professional generation our country.

Language: Английский

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Prescriptions of antidepressants and anxiolytics in France 2012–2022 and changes with the COVID-19 pandemic: interrupted time series analysis

BMJ Mental Health, Journal Year: 2024, Volume and Issue: 27(1), P. e301026 - e301026

Published: Jan. 1, 2024

Background Depression and anxiety have increased in prevalence since the start of COVID-19 pandemic. Objective To evaluate consumption antidepressants anxiolytics from 2012 to 2022 pandemic’s potential impact France. Methods We conducted an interrupted time series analysis routine drug sales data (Medic'AM) all French outpatient pharmacies 2022. investigated trends defined daily doses sold per 1000 inhabitants (DDD/TID) related expenditures before after pandemic onset relation with stringency mitigation measures. Analyses were performed descriptively using segmented linear regression, autoregressive integrated moving average models. Findings From 2019, overall monthly antidepressant (+0.02 DDD/TID) while anxiolytic decreased (−0.07 DDD/TID). With onset, there was a relevant persisting trend increase (+0.20 DDD/TID month) for overall, estimated excess 112.6 May 2020 until December Anxiolytic elevated February throughout but returned expected levels by 2022, 33.8 DDD/TID. There no evident association between or sales. Conclusions This study showed protracted increases temporary. Clinical implications provide evidence that may had long-lasting consequences on treatment depression disorders, requiring further actions researchers policy-makers address this public mental health crisis.

Language: Английский

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Utilization of antidepressants, anxiolytics, and hypnotics during the COVID-19 pandemic

Translational Psychiatry, Journal Year: 2024, Volume and Issue: 14(1)

Published: April 4, 2024

Abstract Since the onset of COVID-19 pandemic, there have been concerns over mental health impact COVID-19. This is a review utilization antidepressants, anxiolytics, and hypnotics since pandemic was declared on March 11th 2020. A number reports so far based large prescription databases for administrative use at national or regional level, but mainly in high-income countries. We found studies reporting increased rates during 2020, which has interpreted as hoarding such medications. In following months, most antidepressant did not display clear pattern change compared with prepandemic trends. later phases small increases higher than predicted rates, consistent finding, especially youth. countries, were increasing trends antidepressants also before needs to be considered when estimating whereas anxiolytics hypnotics, patterns prescriptions more varying. Overall, after 2020 we could find any distinct changes pandemic. Most contain information about prevalence indicated psychiatric disorders studied populations. More are needed long-term effects COVID-19, particularly regarding antidepressants. Research relating major depression anxiety would promote better understanding how well reflect population.

Language: Английский

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Psychotropic Medication Prescribing for Children and Adolescents After the Onset of the COVID-19 Pandemic

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(4), P. e247965 - e247965

Published: April 23, 2024

Importance Numerous studies have provided evidence for the negative associations of COVID-19 pandemic with mental health, but data on use psychotropic medication in children and adolescents after onset are lacking. Objective To assess rates trends prescribing before over 2 years France. Design, Setting, Participants This cross-sectional study used nationwide interrupted time-series analysis outpatient drug dispensing from IQVIA X-ponent database. All 8 839 143 prescriptions dispensed to (6 11 age) (12 17 between January 2016 May 2022 France were retrieved analyzed. Exposure Onset pandemic. Main outcomes Measures Monthly per 1000 analyzed using a quasi-Poisson regression (March 2020), percentage changes assessed. After onset, rate ratios (RRs) calculated estimated expected monthly prescription rates. Analyses stratified by class (antipsychotic, anxiolytic, hypnotic sedative, antidepressant, psychostimulant) age group (children, adolescents). Results In total, analyzed, 5 884 819 [66.6%] 954 324 [33.4%] children. 2016, was 9.9 adolescents, prepandemic increasing 0.4% month (95% CI, 0.3%-0.4%). March 2020, dropped 11.5% −17.7% −4.9%). During following trend changed significantly, increased 1.3% 1.2%-1.5%), reaching 16.1 2022. exceeded 11% (RR, 1.11 [95% 1.08-1.14]). Increases observed all classes substantial anxiolytics, hypnotics sedatives, antidepressants. Prescription rose above those except psychostimulants 1.12 1.09-1.15] 1.06 1.05-1.07] antipsychotics; RR, 1.30 1.25-1.35] 1.09-1.12] anxiolytics; 2.50 2.23-2.77] 1.40 1.30-1.50] sedatives; 1.38 1.29-1.47] 1.23 1.20-1.25] antidepressants; 0.97 0.95-0.98] 1.02 1.00-1.04] psychostimulants). Changes more pronounced among than Conclusions Relevance These findings suggest that medications significantly persistently onset. Future research should identify underlying determinants improve psychological trajectories young people.

Language: Английский

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Psychotropic drug prescribing before and during the COVID-19 pandemic among people with depressive and anxiety disorders: a multinational network study

The Lancet Psychiatry, Journal Year: 2024, Volume and Issue: 11(10), P. 807 - 817

Published: Sept. 3, 2024

Language: Английский

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Sales trends of psychotropic drugs in the COVID-19 pandemic: A national database study in Brazil

Frontiers in Pharmacology, Journal Year: 2023, Volume and Issue: 14

Published: March 17, 2023

Background: The social restrictions among coronavirus disease 2019 (COVID-19) pandemic have posed a thoughtful risk to mental health and implications in the use of drugs, including antidepressants, anxiolytics other psychotropics. Objective: This study analyzed sales data psychotropics prescribed Brazil, order verify change consumption trends these drugs during COVID-19 pandemic. Methods: interrupted time-series psychotropic data, between January 2014 July 2021, using National System Controlled Products Management from Brazilian Health Regulatory Agency. monthly mean DDDs per 1,000 inhabitants day was evaluated by analysis variance (ANOVA) followed Dunnett Multiple Comparisons Test. changes studied were Joinpoint regression. Results: During period studied, clonazepam, alprazolam, zolpidem escitalopram most sold Brazil. According regression, an upward trend observed pregabalin, escitalopram, lithium, desvenlafaxine, citalopram, buproprion amitriptyline. An increase noted throughout period, with maximum (2.61 DDDs) occurring April downward that accompanied drop number deaths. Conclusions: sales, mainly antidepressants pandemic, draws attention issues related population on need for greater monitoring dispensing drugs.

Language: Английский

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The Mediating Role of Depression and of State Anxiety οn the Relationship between Trait Anxiety and Fatigue in Nurses during the Pandemic Crisis

Healthcare, Journal Year: 2023, Volume and Issue: 11(3), P. 367 - 367

Published: Jan. 28, 2023

The coronavirus pandemic (COVID-19) is a global health crisis with particular emotional and physical impact on professionals, especially nurses. aim of this study was to investigate the prevalence anxiety, depression fatigue their possible relationships among nurses during pandemic. population consisted from five tertiary-level public hospitals in Athens who completed Fatigue Assessment Scale (FAS), Beck Depression Inventory (BDI) State-Trait Anxiety (STAI) questionnaires. Gender, age years work experience were recorded. conducted mid-November mid-December 2021. sample included 404 (69 males 335 females) mean 42.88 (SD = 10.90) 17.96 12.00) experience. Symptoms noted 60.4% participants, while 39.7% had symptoms depression, 60.1% abnormal scores state anxiety 46.8% trait females showing higher all scales (p < 0.05). High positive correlations 0.01) found between FAS, BDI, State Trait scales. Regression analysis showed that 51.7% variance FAS can be explained by an additional 6.2% BDI 1.2% anxiety. Mediation mediate relationship FAS. Finally, exert moderating role fatigue. In conclusion, our continue high rates variation appears significantly dependent Depressive symptomatology parallel mediation fatigue, exhibiting relationship.

Language: Английский

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Generation COVID: Young adult substance use

Current Opinion in Psychology, Journal Year: 2023, Volume and Issue: 52, P. 101640 - 101640

Published: June 17, 2023

Language: Английский

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Prescription Trends of Medications Used to Treat Sleep Disturbances in School-aged Children: An Interrupted Time-Series Analysis in France, 2016-2023

The Journal of Pediatrics, Journal Year: 2025, Volume and Issue: unknown, P. 114502 - 114502

Published: Feb. 1, 2025

To assess rates and trends of hypnotic medication prescriptions for children adolescents. Cross-sectional study national dispensing data between January 1, 2016, December 31, 2023, in France. Prescriptions medications (hydroxyzine, alimemazine, melatonin, Z-drugs) dispensed to aged 6 17 years were analyzed. Monthly per 1,000 modeled before after the pandemic onset (March 2020) rate trend changes. Rate ratios (RR) calculated estimated expected prescription rates. Overall, 2,675,142 an average yearly population 9,963,497 children. In was at 1.9 6.8 with post-pandemic exceeding by 131% (RR: 2.31, 95%CI: 2.08; 2.54). Prescription increased all from -0.1% (95%CI: -0.2;0.1%) month pre-pandemic +1.4% 1.2;1.6%) hydroxyzine; +0.1% 0.0;0.2%) +0.9% 0.7;1.0%) alimemazine; +2.2% 2.0;2.3%) +4.4% 3.9;4.9%) melatonin; -3.2% -3.6;-2.8%) +1.8% 1.4;2.2%) Z-drugs. exceeded 38% 1.38, 1.31;1.46) 19% 1.19, 1.15;1.22) 344% 4.44, 4.07;4.80) 419% 5.19, 4.24;6.14) Recent substantial increases prescribing are possibly related their persistently deteriorating mental health, changes strategies, and/or unmet pre-existing needs.

Language: Английский

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A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study

BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 7, 2025

There is a growing concern and debate over the inappropriate use of analgesics psychotropic medications by older adults, especially those with dementia. The long-term effects COVID-19 pandemic lockdown measures on these prescriptions remain uncertain. primary aim was to examine changes in prescription (opioids other analgesics) psychotropics (anxiolytics/sedatives, antidepressants, antipsychotics) Norwegian home-dwelling adults before, during, up 2 years after lockdown, particular focus dementia status. Secondarily, we explored individual characteristics associated medication prescriptions. A prospective cohort study using baseline data from 10,464 participants (54% females, mean age 76 [SD 5.8]) Trøndelag Health Study (HUNT4 70+) linked Prescription Database. Age- education-adjusted Poisson regression applied fills, multilevel mixed-effects linear used estimate sum defined daily dose (DDD) per person period during (March–September 2020) compared that corresponding months (March–September) 2019, 2021, 2022. Overall, opioids, analgesics, anxiolytics/sedatives were higher 2022 than lockdown. People without had increased antidepressants whereas no observed among Increases anxiolytics/sedatives, between occurred mainly aged < 80 years, comorbidities or mental distress, good physical function, low fear COVID-19, social isolation COVID-19. An increase predominantly younger-old healthier participants. This indicates high-income countries, such as Norway, vulnerable individuals seem have received adequate care. However, may number individuals. These findings should be considered when identifying future nationwide stressors impair interactions threaten health. They also highlight need evaluate for pandemic. registered ClinicalTrials.gov 02.02.2021, identification NCT 04792086.

Language: Английский

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