Brief Report: A population-based study of the impact of the COVID-19 pandemic on benzodiazepine use among children and young adults

European Child & Adolescent Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 7, 2024

The COVID-19 pandemic was associated with increases in the prevalence of depression and anxiety among children young adults. We studied whether changes prescription benzodiazepine use. conducted a population-based study dispensing to adults ≤ 24 years old between January 1, 2013, June 30, 2022. used structural break analyses identify month(s) when occurred, interrupted time series models quantify following compare observed expected A occurs where there is sudden change trend series. an immediate decline 23.6 per 100,000 (95% confidence interval [CI]: -33.6 -21.2) April 2020, followed by monthly decrease 0.3 CI: -0.74 0.14). Lower than rates were each month from 2020 onward, relative percent differences ranging - 7.4% -10.1% 4.7%) -20.9% -23.2% -18.6%). Results generally similar stratified sex, age, neighbourhood income quintile, urban versus rural residence. Further research required understand clinical implications these findings trends sustained further follow-up.

Language: Английский

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UV/Chlorine-BAC treatment of antidepressant drug in drinking water: efficacy, process optimization, and microbiological characterization

Frontiers of Environmental Science & Engineering, Journal Year: 2024, Volume and Issue: 18(10)

Published: Aug. 10, 2024

Language: Английский

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A multicenter retrospective study of antidepressant use in outpatient clinics in China pre- and post-COVID

International Journal of Clinical Pharmacy, Journal Year: 2024, Volume and Issue: 46(5), P. 1215 - 1224

Published: Aug. 14, 2024

Language: Английский

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Trends in Nonfatal Overdose Rates Due to Alcohol and Prescription and Illegal Substances in Colombia, 2010–2021

American Journal of Public Health, Journal Year: 2024, Volume and Issue: unknown, P. e1 - e9

Published: Sept. 12, 2024

Objectives. To examine drug overdoses in Colombia by type of substance, sex, age, and intent using data from a health surveillance system 2010 to 2021. Methods. We characterized year, sociodemographic variables. calculated age-adjusted overdose rates substance type, age groups, intent. used Poisson regression models trend differences across sex groups. Results. Age-adjusted increased 8.51 40.52 per 100 000 during Men, compared with women, had higher for every except opioids psychotropics. Drug involving cannabis stimulants steadily until 2017 but decreased afterward. Overdose psychotropic medication greatly 2018 2021, mainly because intentional young women. Conclusions. Overdoses illegal drugs recent years Colombia; however, the continuous increase highlights need prevention efforts curb this trend. Health systems are an important tool that can guide countries limited resources. ( Am J Public Health. Published online ahead print September 12, 2024:e1–e9. https://doi.org/10.2105/AJPH.2024.307786 )

Language: Английский

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Innovative analysis of diazepam, zolpidem and their main metabolites in human urine by micelle-to-solvent stacking in capillary electrophoresis

Journal of Pharmaceutical and Biomedical Analysis, Journal Year: 2023, Volume and Issue: 239, P. 115898 - 115898

Published: Dec. 4, 2023

Language: Английский

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