Association between urbanicity and depressive symptoms among Chinese middle-aged and older adults

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Abstract Background Depression is a pressing public health issue and may be affected by multifaceted urban living, yet the specific urbanicity elements associated unclear. Using multidimensional scale, we explored association between its components with risk of depressive symptoms. Methods This study used data from four waves China Health Retirement Longitudinal Study, including 12,515 participants aged ≥45 years at baseline in 2011 450 rural communities, 8,766 7 follow-up. Multilevel logistics regression Cox proportional hazards models examined cross-sectional longitudinal associations Results Living areas highest tertile was 61% lower symptoms cross-sectionally (odds ratio (OR): 0.39, 95% confidence interval (CI): 0.30-0.50) 33% longitudinally (hazard (HR): 0.67, CI: 0.58-0.77) compared to those living lowest urbanicity. Among components, higher population density (OR: 0.92, 0.87-0.97), better education 0.94, 0.89-0.99), transportation 0.95, 0.92-0.98), sanitation 0.96, 0.93-0.98) odds symptoms, while greater educational socioeconomic diversity (OR, 1.08; CI, 1.03-1.13) had opposite effect. Better economic conditions (HR: 0.90-0.98) availability social services (HR, 0.96; 0.93-0.99) were reduced developing during Additionally, differences found residents midlife older adults. Conclusions Our findings underscore complex links among middle-aged adults, highlighting need consider perspective understand urbanicity-mental nexus. Tailored planning policies should along temporal effectiveness, urban-rural disparities, age group differences.

Language: Английский

Association of TyG Index and TG/HDL-C Ratio with Trajectories of Depressive Symptoms: Evidence from China Health and Retirement Longitudinal Study

Nutrients, Journal Year: 2024, Volume and Issue: 16(24), P. 4300 - 4300

Published: Dec. 12, 2024

Objectives: To explore whether the triglyceride–glucose (TyG) index and triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio are associated with trajectories of depressive symptoms. Methods: In this longitudinal study, 4215 participants aged 45 years older were recruited from China Health Retirement Longitudinal Study 2011 2018. The symptoms, measured by 10-item Center for Epidemiologic Studies Depression Scale (CESD-10), identified using group-based trajectory modeling. Multinomial logistic models restricted cubic spline analysis used investigate relationships between TyG TG/HDL-C Stratified analyses conducted based on sex, age, place residence, body mass (BMI). Results: Five distinct symptoms characterized stable low, moderate, decreasing, increasing, high during a follow-up 7 years. associations not entirely consistent. After adjusting covariates, higher at baseline was lower odds being decreasing (ORad = 0.61, 95% CI: 0.40–0.92) compared low trajectory, revealed negative linear relationship likelihood However, no longer statistically significant when all confounders controlled 0.72, 0.50−1.04). Additionally, association observed among 45–64-year-old individuals, female participants, those living in rural areas, normal BMI. Limitations: This study middle-aged elderly population China, extrapolation other regions populations requires further confirmation. Conclusions: Compared ratio, may be better predictor adults. Considering that pathology depression progresses long term, our findings have utility identifying available reliable markers development depression.

Language: Английский