Author's reply to letter to the editor regarding “Impact of ketamine on incidence of postoperative depression: Re-analysis using a more targeted approach” DOI
Qingfeng Wei, Mengmeng Li, Yu Jiang

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 358, P. 350 - 352

Published: May 6, 2024

Language: Английский

Ketamine and its two enantiomers in anesthesiology and psychiatry: A historical review and future directions DOI Creative Commons
Kenji Hashimoto, Mingming Zhao, Tingting Zhu

et al.

Journal of Anesthesia and Translational Medicine, Journal Year: 2024, Volume and Issue: 3(3), P. 65 - 75

Published: July 11, 2024

Ketamine, a dissociative anesthetic, is widely utilized in both human and veterinary anesthesia. Its (S)-enantiomer, esketamine, similarly employed for anesthesia analgesia. The anesthetic effects of ketamine esketamine arise from their antagonism the N-methyl-D-aspartate receptor (NMDAR). In field psychiatry, rapid-acting antidepressant properties severe depression have generated significant interest, resulting its increased off-label usage United States (U.S.). 2019, nasal spray received approval use U.S. Europe. However, concerns emerged regarding potential adverse effects, including long-term efficacy, addiction risks, suicide risk clinical settings. contrast, arketamine, (R)-enantiomer ketamine, exhibits superior longer-lasting rodent models depression, with fewer side compared to esketamine. Nevertheless, research on efficacy safety arketamine patients remains limited. This article provides concise exploration historical two enantiomers while also delving into future directions application these fields.

Language: Английский

Citations

11
Effect of esketamine on postoperative depression in women with breast cancer and preoperative depressive symptoms: The EASE randomized trial DOI
Qingfeng Wei, Mengmeng Li,

Qiuling Du

et al.

Journal of Clinical Anesthesia, Journal Year: 2025, Volume and Issue: 103, P. 111821 - 111821

Published: March 29, 2025

Language: Английский

Citations

0
Impact of ketamine on incidence of postoperative depression: Re-analysis using a more targeted approach DOI
I‐Wen Chen,

Chia‐Li Kao,

Kuo‐Chuan Hung

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 355, P. 526 - 527

Published: April 5, 2024

Language: Английский

Citations

1
Author's reply to letter to the editor regarding “Impact of ketamine on incidence of postoperative depression: Re-analysis using a more targeted approach” DOI
Qingfeng Wei, Mengmeng Li, Yu Jiang

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 358, P. 350 - 352

Published: May 6, 2024

Language: Английский

Citations

0