The association between red blood cell distribution width-to-albumin ratio and risk of depression: A cross-sectional analysis of NHANES

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 379, P. 250 - 257

Published: March 12, 2025

Language: Английский

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Relative fat mass as a predictor of gallstones: insights from national health and nutrition examination survey data

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 1, 2025

Gallstones have been linked to obesity. Relative fat mass (RFM) has emerged as a novel obesity index that more precisely represents the body distribution. The correlation between RFM and risk of developing gallstones remains unclear. This study aims explore prevalence gallstones. A cross-sectional analysis was conducted on data from NHANES 2017–2020. formation examined through multivariate logistic regression, receiver operating characteristic (ROC) curve, sensitivity analysis, subgroup restricted cubic spline regression. Among 12,947 subjects, 1362 were categorized having It observed quartile range increased, with notable rise in (3.7% vs. 7.5% 9.8% 21.1%, P < 0.001). Logistic RCS regression analyses indicated significantly positive linear gallstones, even after accounting for confounders potential (adjusted OR = 1.075, 95% CI: 1.050, 1.101). There is still significant across both analyses. ROC (AUC 0.696, 95%CI: 0.682, 0.711) can serve robust identify compared traditional anthropometric indices. first provide evidence However, further prospective studies are needed validate these findings.

Language: Английский

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Association between relative fat mass and periodontitis: results from NHANES 2009–2014

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Aug. 6, 2024

Relative fat mass (RFM) is a novel indicator for measuring body fat. This cross-section study aims to explore the association between RFM and periodontitis investigate possible effect modifiers in U.S. adults based on National Health Nutrition Examination Survey 2009-2014. The category of was defined by CDC/AAP. Mean clinical attachment loss mean pocket probing depth (PPD) were calculated. formula is: 64 - (20 × height/WC) + (12 sex), with sex coded as 1 female 0 male. Natural cubic spline weighted multivariable regression analyses conducted relationship periodontal status. Subgroup interaction also employed assess moderating roles age, gender, race. A total 10,307 participants included our study. Compared lowest quartiles, individuals highest quartiles levels more likely have moderate/severe (ORQ4vs1 = 1.64, 95% CI 1.30-2.06) had higher PPD (βQ4vs1 0.15, 0.09-0.22). particularly stronger populations under age 60, significant interactions. Taken together, positively associated periodontitis, those 60 years old.

Language: Английский

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Association between novel anthropometric indices and overactive bladder: a population-based study

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 22, 2025

Background Abdominal obesity is recognized as a key risk factor for developing OAB. However, traditional measures of obesity, such the waist-to-height ratio (WHtR), waist circumference, and body mass index (BMI), may not sufficiently capture fat distribution in body. This study aims to evaluate relationship between novel anthropometric indices OAB, providing more accurate assessment obesity-related factors. Methods The National Health Nutrition Examination Survey (NHANES) data from 2007 2018 were utilized, comprising 27,560 participants. To assess association discriminative ability indices, including Body Roundness Index (BRI), A Shape (ABSI), Waist-to-Weight (WWI), Relative Fat Mass (RFM), with we employed multivariable logistic regression, restricted cubic spline (RCS) analysis, subgroup receiver operating characteristic (ROC) curve methods. Results Multivariable regression analysis indicated that higher levels positively associated OAB prevalence. One z-score increase WWI, BRI, RFM, ABSI was 16, 31, 57, 5% likelihood respectively. RCS revealed non-linear RFM ROC WWI (AUC = 0.680) 0.661) provided better diagnostic accuracy than BMI 0.599). Subgroup analyses supported robustness these findings. Conclusion Novel demonstrated significantly value WHtR. Future studies should investigate potential combining multiple improve predictive conduct prospective determine causality.

Language: Английский

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Relative Fat Mass, A Better Predictor of Erectile Dysfunction: Insights From the NHANES 2001–2004

American Journal of Men s Health, Journal Year: 2025, Volume and Issue: 19(1)

Published: Jan. 1, 2025

Obesity is a significant factor contributing to erectile dysfunction (ED). Early detection of ED generally results in improved treatment outcomes. Our study aims elucidate the association between relative fat mass (RFM) and by analyzing data from National Health Nutrition Inspection Survey (NHANES) spanning 2001 2004. We used NHANES 2001–2004, employing weighted, multivariable-adjusted logistic regression assess relationship RFM risk ED. Additional analyses included subgroup analysis, smooth curve fitting, threshold effect analysis. Subsequently, predictive utility RFM, body index (BMI), waist circumference (WC) for was evaluated using receiver operating characteristic area under (AUC) calculations. A total 3,947 American male participants were this retrospective within NHANES. Weighted multivariate analysis indicated that, after adjusting potential confounding factors, positively associated with (OR = 1.03, 95% CI 1.01-1.05, p < .001). No saturation effects observed (all ps > .05). In addition, demonstrated superior capability (AUC 0.644) compared BMI 0.525) WC 0.612). findings suggest that higher levels are an increased ED, highlighting its as marker condition.

Language: Английский

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Association between current relative fat mass and history of female infertility based on the NHANES survey

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 21, 2025

Language: Английский

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Predictive factors and risk model for depression in patients with type 2 diabetes mellitus: a comprehensive analysis of comorbidities and clinical indicators

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: March 5, 2025

Depression is highly prevalent among individuals with type 2 diabetes mellitus (T2DM), often compounded by multiple chronic conditions. This study aimed to identify the key factors influencing depression in this population, a particular focus on relationship between Cumulative Illness Rating Scale (CIRS) score and depression, evaluate predictive value of model incorporating sex, body mass index (BMI), low-density lipoprotein cholesterol (LDL-C), CIRS score. A total 308 hospitalized patients from Quzhou Hospital, Wenzhou Medical University were enrolled. Their clinical biochemical data collected, alongside assessments comorbidities depressive symptoms using Self-Rating (SDS), respectively. LASSO regression 10-fold cross-validation was used optimal variables for model. Multivariate analysis performed assess independent associations BMI, LDL-C, depression. The scores further explored across various subgroups. model's assessed through ROC curve analysis. Female sex (OR: 2.48, 95% CI: 1.50-4.10, p < 0.001), lower BMI 0.92, 0.86-0.98, = 0.015), LDL-C 0.77, 0.61-0.98, 0.031), higher 1.11, 1.05-1.18, 0.001) independently linked after adjusting variables. strong association observed, particularly males, under 60 years old, those disease duration less than 5 years, no history smoking or alcohol consumption. Additionally, demonstrated high accuracy identifying at risk Female, associated diabetes. appeared be more effective predicting people who male, younger, shorter DM duration, drinking. comprehensive prediction could help clinicians are

Language: Английский

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The relationship between VAI, LAP, and depression and the mediation role of sleep duration–evidence from NHANES 2005–2020

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 11, 2025

The relationship between obesity and mental health has attracted attention. However, large sample studies on the visceral fat depression are lacking. This study aimed to explore by using adiposity index (VAI) lipid accumulation product (LAP). Additionally, it sought potential mediating role of sleep duration in these associations. data used current cross-sectional investigation from National Health Nutrition Examination Survey (NHANES) spanning 2005 2020, including 19,659 participants. Depression was measured nine-item Patient Questionnaire. Weighted multivariable regression analysis evaluate correlation VAI LAP with depression. non-linear determined smooth curve fitting threshold effect analysis. mediation performed investigate duration. stability assessed through sensitivity were closely related In fully adjusted model, highest quartile increased association 52% (OR = 1.52, 95% CI 1.20–1.92, P < 0.001) 51% 1.51, 1.19–1.91, 0.001), respectively, compared lowest quartile. Specific saturation effects for VAI, LAP, identified smoothed fitting, inflection points 3.81 98.55, respectively. revealed that 5.1% 2.8% associations mediated results showed interactions hypertension cardiovascular disease (P 0.05). associated US adults. non-linear, which may be highlights as valuable tools prevention management

Language: Английский

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Systemic inflammation response index mediates the association between relative fat mass and psoriasis risk: a population-based study

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: March 27, 2025

Psoriasis, a prevalent autoimmune skin condition, considerably impairs the quality of life those who are affected by it. Several studies have demonstrated that obesity significantly contributes to both onset and progression psoriasis. Relative fat mass (RFM), novel index, provides more precise measure incorporating height waist circumference (WC). The aim this study was investigate association between RFM psoriasis risk, taking into account intermediary role played systemic inflammation response index (SIRI). cross-sectional assessed data from 8,479 adults participated in NHANES cycles 2003 2006 2009 2014. To examine psoriasis, multivariate logistic regression model restricted cubic spline (RCS) analyses were conducted. A mediation analysis used clarify SIRI Higher associated with 5% higher risk developing (odds ratio [OR] = 1.05, 95% confidence interval [CI]:1.02–1.08), quartiles indicating significant trend (P for < 0.05). mediating effect on RFM-psoriasis relationship (mediation 5.02%). Elevated an increased prevalence has potential be beneficial anthropometric accurately predicting risk.

Language: Английский

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Association between relative fat mass and cognitive function among US older men: NHANES 2011–2014

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

Background This study aimed to investigate the relationship between cognitive performance and relative fat mass (RFM) in older American males.Methods For purpose of this cross-sectional research, a total 1,321 individuals were selected from National Health Nutrition Examination Survey (NHANES), which was carried out years 2011 2014. Specifically, Consortium Establish Registry for Alzheimer’s Disease Word Learning Test (CERAD-WL), Animal Fluency (AFT), Digit Symbol Substitution (DSST) used order achieve objective assessing function. Z-scores calculated as composite, generalized metric by taking average standardized scores three previously mentioned assessments. RFM ascertained measuring waist circumference (WC) height. Multivariate linear regression, threshold effect analyses, smooth curve fitting, subgroup analyses undertaken connections that exist function.Results The included male volunteers who at least 60 old, complete data provided each individual. Fully adjusted models indicated negative correlation CERAD-WL scores[-0.17, (-0.32,-0.01)], DSST scores[-0.83, (-1.16,-0.50)] Z-scores[-0.03, (-0.05, -0.01)]. It observed became more pronounced when exceeded 35.78. Furthermore, showed association function significantly impacted education level, poverty-income ratio (PIR), smoking status, drinking status.Conclusions In elderly men, higher linked lower function, suggesting management may prove advantageous mitigating decline among populations.

Language: Английский

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