Evaluating the global prevalence of insomnia during pregnancy through standardized questionnaires and diagnostic criteria: a systematic review and meta-analysis DOI Creative Commons
Chengcheng Yang, Rui Fu, Huan Wang

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 13, 2024

Introduction Insomnia during pregnancy presents significant medical care challenges and heightens the risk of adverse outcomes for both pregnant women fetuses. This study undertook a meta-analysis to assess global prevalence insomnia pregnancy, examining overall regional variations. Method The aim this was perform articles indexed in PubMed, Embase, Web Science from inception these databases up February 29, 2024. systematically reviewed gestational explored potential moderating factors, encompassing research type, publication date, influences, maternal age, status, depressive symptoms, anxiety symptoms. Result Forty-four studies, total 47,399,513 participants, were included analysis. symptoms 43.9%. Regional factors depression emerged as main affecting insomnia, with Europe (53.6%) surpassing North America (41.0%), followed by South (50.6%) Asia (40.7%). High rates (56.2%) correlated increased compared low (39.8%). type date showed no impact on Conclusion results indicated that higher especially among who highly depressed state or located European region. Systematic review registration PROSPERO, identifier CRD42018104460.

Language: Английский

Effects of hyperbaric oxygen on inflammation and oxidative stress in PCPA-induced insomnia rat models DOI Creative Commons
Mengmeng Wang,

Yao Yang,

Yue Fu

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: June 10, 2024

Abstract To clarify the effect and mechanism of hyperbaric oxygen (HBO) on insomnia, SD rats were divided randomly into PCPA, HBO+PCPA Control group (n=8). Rat insomnia model was established by intraperitoneal injection para-chlorophenylalanine (PCPA), then 2.0ATA-60min HBO given. After intervention, general behavior, sleep status, brain tissue pathology, serum inflammatory oxidative stress molecules measured. Compared with group, in PCPA showed circadian rhythm reversal, daytime time reduction, weight loss temper irritability. Sleep latency significantly prolonged duration shortened group. All above changes improved intervention. Positive Nissl staining hippocampus, prefrontal cortex hypothalamus largely decreased compared controls, which obviously reversed Moreover, IL-1β, IL-6, IL-17A, TNF-Α MDA markedly increased, while IL-10, IL-12p70 SOD to Controls. When intervention can decrease levels MDA, increased serum. relieve PCPA-induced rat symptoms, reduce inflammation injury vivo, is one mechanisms treatment for insomnia.

Language: Английский

Citations

0
Evaluating the global prevalence of insomnia during pregnancy through standardized questionnaires and diagnostic criteria: a systematic review and meta-analysis DOI Creative Commons
Chengcheng Yang, Rui Fu, Huan Wang

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 13, 2024

Introduction Insomnia during pregnancy presents significant medical care challenges and heightens the risk of adverse outcomes for both pregnant women fetuses. This study undertook a meta-analysis to assess global prevalence insomnia pregnancy, examining overall regional variations. Method The aim this was perform articles indexed in PubMed, Embase, Web Science from inception these databases up February 29, 2024. systematically reviewed gestational explored potential moderating factors, encompassing research type, publication date, influences, maternal age, status, depressive symptoms, anxiety symptoms. Result Forty-four studies, total 47,399,513 participants, were included analysis. symptoms 43.9%. Regional factors depression emerged as main affecting insomnia, with Europe (53.6%) surpassing North America (41.0%), followed by South (50.6%) Asia (40.7%). High rates (56.2%) correlated increased compared low (39.8%). type date showed no impact on Conclusion results indicated that higher especially among who highly depressed state or located European region. Systematic review registration PROSPERO, identifier CRD42018104460.

Language: Английский

Citations

0