Impact of cardiovascular risk factors on associations between state and trait indices of major depression disorder and objectively assessed physical activity, sleep and circadian rhythmicity within a population based cohort

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 378, P. 360 - 372

Published: Feb. 22, 2025

Language: Английский

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Beyond vision: effects of light on the circadian clock and mood-related behaviours

Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)

Published: March 13, 2025

Abstract Light is a crucial environmental factor that influences various aspects of life, including physiological and psychological processes. While light well-known for its role in enabling humans other animals to perceive their surroundings, influence extends beyond vision. Importantly, affects our internal time-keeping system, the circadian clock, which regulates daily rhythms biochemical processes, ultimately impacting mood behaviour. The 24-h availability can have profound effects on well-being, both physically mentally, as seen cases jet lag shift work. This review summarizes intricate relationships between light, mood-related behaviours, exploring underlying mechanisms implications health.

Language: Английский

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Multi-Modal Sleep Measurement and Alignment Analysis in Outpatients with Major Depressive Episode

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: April 30, 2025

Abstract Study Objectives Sleep plays a crucial role for mental health. This study examines sleep tracking in naturalistic settings patients with major depressive episodes (MDE) using actigraphy, smartphone data, bed sensors, and the ecological momentary assessment (EMA) assesses discrepancies between these modalities. Methods We measured onset, offset, total time (TST) over two weeks 172 participants, including healthy controls three MDE subgroups (borderline personality disorder, bipolar disorder). Agreement measurement modalities was assessed Bland-Altman plots Pearson correlation. Predictors of alignment were analyzed mixed-effects models, accounting demographics, daylight length, participant subgroup. Results Patients showed greater variability than controls. Actigraphy overestimated TST compared to sensors (0.48 min) smartphones (0.99 min), while underestimated other Older age improved actigraphy as well sensor offset. (smartphone vs. sensor) worse females bipolar/borderline patients. Longer duration offset across Conclusions Our highlights biases, seasonal effects, demographic factors associated objective measures. While show potential offer several advantages assessing longer periods, misalignment should be considered future studies or clinical settings. Statement Significance Tracking psychiatric is challenging due frequent disturbances, making accurate diagnosis care. Traditional methods are limited lab settings, restricting long-term monitoring. evaluates self-reports both individuals disorders. findings demonstrate feasibility non-invasive monitor episodes. uncover systematic biases estimates modalities, reveal environmental that influence agreement, populations exhibit more patterns. work addresses critical gap validating consumer-grade technologies contexts.

Language: Английский

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Associations between rest–activity/light-exposure rhythm characteristics and depression in United States adults: A population-based study

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 369, P. 1004 - 1012

Published: Oct. 22, 2024

Language: Английский

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