Merits and demerits of administering esketamine in preventing postpartum depression following cesarean section DOI
Takahiko Nagamine

World Journal of Clinical Cases, Journal Year: 2024, Volume and Issue: 12(36), P. 6883 - 6886

Published: Oct. 30, 2024

Emergency cesarean section is associated with the development of postpartum depression. Esketamine has been demonstrated to have a rapid onset antidepressant effects. Randomized controlled trials and meta-analyses efficacy esketamine in preventing depression after cessarean section. However, data included these analyses were derived from elective sections differed dose timing administration. dissociative anesthetic dose-dependent risk inducing psychotic symptoms, including hallucinations. In setting section, should be administered caution only if potential benefits outweigh risks.

Language: Английский

Effects of epidural esketamine versus sufentanil on labor analgesia and postpartum depression: a retrospective cohort study DOI Creative Commons
Kunyue Li, Ziqi Chai,

Chunyun Deng

et al.

BMC Anesthesiology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 7, 2025

There is a lack of research on epidural esketamine for labor analgesia. The purpose this to compare the efficacy and sufentanil analgesia postpartum depression. A total 187 cephalic full-term parturients with single-fetus vaginal delivery were collected in retrospective study from Jan 2022 2023. Parturients categorized into two groups according anesthetics: group (Group KR, n = 97) patient-controlled 0.3 mg/ml 0.083% ropivacaine 240 ml normal saline Sufentanil SR, 90) µg/ml saline. Visual Analogue Scale, Ramsay Sedation Modified Bromage Score recorded before, 5, 10, 30 min after analgesia, when uterine orifice was fully opened, delivery. Edinburgh Postnatal Depression Scale(EPDS) scores at 3 42 days recorded. maternal infant outcomes occurrence adverse reactions VAS 5,10,30 cervix opened higher Group KR than SR (all P < 0.05). RSS lower Compared significant decreases shown EPDS incidence depression has considerably decreased rates pruritus compared (P other effects showed no difference > neonatal not significantly different between In comparison sufentanil, may exhibit better sedative effect, low pruritus, but limited analgesic effect. It be associated risk Further exploration optimal regimen dosage would necessary.

Language: Английский

Citations

1
Esketamine reduces the risk of postpartum depression in women undergoing cesarean section: a systematic review and meta-analysis DOI Creative Commons

Lőrinc Frivaldszky,

Kincső Lőrincz,

Jakub Hoferica

et al.

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 183, P. 164 - 173

Published: Feb. 14, 2025

Language: Английский

Citations

1
The role of anesthesiologists in postpartum depression: current perspectives and future directions DOI Creative Commons
Weijia Du, Xiaowei Qian,

Zhendong Xu

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: March 19, 2025

Postpartum depression is a common complication of childbirth that can seriously affect women, infants, and families. In 2020, the National Health Commission People’s Republic China mandated anxiety screenings during pregnancy postpartum visits to ensure timely medical intervention referrals appropriate behavioral health resources. Anesthesiologists are indispensable members in obstetric practice. Optimal peripartum pain control reduce stress response; promote breastfeeding; lower maternal depression. Recently, discovery rapid sustained antidepressant properties ketamine emerging evidence supporting effectiveness anesthetic drugs treatment depressive disorders have positioned anesthesiologists on new frontier for treating neuropsychiatric disorders. This review aimed explore impact labor epidural analgesia, anesthesia, while discussing role its prevention based recent evidence.

Language: Английский

Citations

0
Rapid-Acting Treatments for Perinatal Depression: Clinical Landscapes and Future Horizons DOI Open Access
Emily Beydler, Amanda Koire, Elizabeth R. Steuber

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2025, Volume and Issue: 22(4), P. 546 - 546

Published: April 2, 2025

Perinatal depression affects approximately 1 in 5 women and is the leading cause of maternal mortality United States. In addition to evidence-based treatment with antidepressant medications, there has been a push identify rapid-acting options for pregnant postpartum individuals. This paper reviews evidence behind new pharmacological agents (neurosteroids ketamine) non-pharmacological approaches (transcranial magnetic stimulation). The also highlights risks benefits electroconvulsive therapy selective serotonin reuptake inhibitors. Based on recent studies research, provides considerations when prescribing these modalities including: timing symptom onset, severity presentation, breastfeeding priorities, prior response availability cost.

Language: Английский

Citations

0
Postpartum Depression and Child Mental Health Outcomes: Evidenced-Based Interventions DOI

Eliza M. Wierzbinska,

Leah C. Susser

Current Treatment Options in Psychiatry, Journal Year: 2025, Volume and Issue: 12(1)

Published: April 15, 2025

Language: Английский

Citations

0
Merits and demerits of administering esketamine in preventing postpartum depression following cesarean section DOI
Takahiko Nagamine

World Journal of Clinical Cases, Journal Year: 2024, Volume and Issue: 12(36), P. 6883 - 6886

Published: Oct. 30, 2024

Emergency cesarean section is associated with the development of postpartum depression. Esketamine has been demonstrated to have a rapid onset antidepressant effects. Randomized controlled trials and meta-analyses efficacy esketamine in preventing depression after cessarean section. However, data included these analyses were derived from elective sections differed dose timing administration. dissociative anesthetic dose-dependent risk inducing psychotic symptoms, including hallucinations. In setting section, should be administered caution only if potential benefits outweigh risks.

Language: Английский

Citations

0