Automated Identification of Aspirin-Exacerbated Respiratory Disease Using Natural Language Processing and Machine Learning: Algorithm Development and Evaluation Study DOI Creative Commons
Thanai Pongdee, Nicholas B. Larson, Rohit Divekar

et al.

JMIR AI, Journal Year: 2023, Volume and Issue: 2, P. e44191 - e44191

Published: May 22, 2023

Background Aspirin-exacerbated respiratory disease (AERD) is an acquired inflammatory condition characterized by the presence of asthma, chronic rhinosinusitis with nasal polyposis, and hypersensitivity reactions on ingestion aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Despite AERD having a classic constellation symptoms, diagnosis often overlooked, average greater than 10 years between onset symptoms AERD. Without diagnosis, individuals will lack opportunities to receive effective treatments, such as desensitization biologic medications. Objective Our aim was develop combined algorithm that integrates both natural language processing (NLP) machine learning (ML) techniques identify patients from electronic health record (EHR). Methods A rule-based decision tree incorporating NLP-based features developed using clinical documents EHR at Mayo Clinic. From notes, NLP techniques, 7 were extracted included following: AERD, NSAID allergy, polyps, sinusitis, elevated urine leukotriene E4 level, documented no-NSAID allergy. MedTagger used extract these unstructured text given set keywords patterns based chart review 2 allergy immunology experts for The status each feature quantified assigning frequency its occurrence in per subject. We optimized classifier’s hyperparameters cutoff threshold training determine representative combination discriminate then evaluated resulting model test set. Results algorithm, which combines ML achieved area under receiver operating characteristic curve score, sensitivity, specificity 0.86 (95% CI 0.78-0.94), 80.00 70.82-87.33), 88.00 79.98-93.64) set, respectively. Conclusions promising needs further refinement improve diagnosis. Continued development technologies has potential reduce diagnostic delays our patients.

Language: Английский

Exploring the Intersection of Artificial Intelligence and Clinical Healthcare: A Multidisciplinary Review DOI Creative Commons
Celina Silvia Stafie, Irina-Georgeta Șufaru, Cristina Mihaela Ghiciuc

et al.

Diagnostics, Journal Year: 2023, Volume and Issue: 13(12), P. 1995 - 1995

Published: June 7, 2023

Artificial intelligence (AI) plays a more and important role in our everyday life due to the advantages that it brings when used, such as 24/7 availability, very low percentage of errors, ability provide real time insights, or performing fast analysis. AI is increasingly being used clinical medical dental healthcare analyses, with valuable applications, which include disease diagnosis, risk assessment, treatment planning, drug discovery. This paper presents narrative literature review use from multi-disciplinary perspective, specifically cardiology, allergology, endocrinology, fields. The highlights data recent research development efforts for healthcare, well challenges limitations associated implementation, privacy security considerations, along ethical legal concerns. regulation responsible design, development, still early stages rapid evolution field. However, duty carefully consider implications implementing respond appropriately. With potential reshape delivery enhance patient outcomes, systems continue reveal their capabilities.

Language: Английский

Citations

55

Artificial Intelligence: Exploring the Future of Innovation in Allergy Immunology DOI Open Access
Derek MacMath, Meng Chen, Paneez Khoury

et al.

Current Allergy and Asthma Reports, Journal Year: 2023, Volume and Issue: 23(6), P. 351 - 362

Published: May 9, 2023

Language: Английский

Citations

31

Health informatics to enhance the healthcare industry's culture: An extensive analysis of its features, contributions, applications and limitations DOI Creative Commons
Mohd Javaid, Abid Haleem, Ravi Pratap Singh

et al.

Informatics and Health, Journal Year: 2024, Volume and Issue: 1(2), P. 123 - 148

Published: June 13, 2024

Health informatics is a fast-growing area in the healthcare sector. It concerns technologies, tools, equipment, and procedures required to gather, store, retrieve, use health data medical data. Healthcare provides patients, nurses, hospital administrators, physicians, insurance providers, other stakeholders with electronic access records through information technologies (HIT). combines nursing science analytical disciplines handle, interpret, convey data, bringing together specialists making accessible meaningful. This research an outcome of extensive scopic review, which has been conducted by identifying development search keywords such as "Health informatics," "Technologies," "Healthcare" from databases Scopus, PubMed, Google Scholar, ResearchGate, platforms. Further, most relevant papers are identified studied. paper explores informatics, its their need present domain. also identifies vital aspects, characteristics, versatile contributions discusses significant applications field. Patients' can be effectively analysed individually or groups using meet diverse requirements. Effective improves practice management quickly shared among professionals, patients stakeholders. specialists' knowledge utilising assist choice-making creating best practices. enables organisations identify specific offering appropriate for given therapy, procedure, training. Informatics addresses issues at macro level organisation personal patient care via innovative

Language: Английский

Citations

16

Artificial intelligence in Immuno-genetics DOI Creative Commons
Raed Farzan

Bioinformation, Journal Year: 2024, Volume and Issue: 20(1), P. 29 - 35

Published: Jan. 31, 2024

Rapid advancements in the field of artificial intelligence (AI) have opened up unprecedented opportunities to revolutionize various scientific domains, including immunology and genetics. Therefore, it is interest explore emerging applications AI genetics, with objective enhancing our understanding dynamic intricacies immune system, disease etiology, genetic variations. Hence, use methodologies immunological datasets, thereby facilitating development innovative approaches realms diagnosis, treatment, personalized medicine reviewed.

Language: Английский

Citations

15

A systematic review of allergen cross-reactivity: Translating basic concepts into clinical relevance DOI Creative Commons
Ekansh Sharma, Joana Vitte

Journal of Allergy and Clinical Immunology Global, Journal Year: 2024, Volume and Issue: 3(2), P. 100230 - 100230

Published: Feb. 19, 2024

Access to the molecular culprits of allergic reactions allows for leveraging allergology as a new precision medicine approach-one built on interdisciplinary, basic, and clinical knowledge. Molecular relies use allergen molecules

Language: Английский

Citations

13

A Conceptual Framework for Applying Ethical Principles of AI to Medical Practice DOI Creative Commons
Debesh Jha, Görkem Durak, Vanshali Sharma

et al.

Bioengineering, Journal Year: 2025, Volume and Issue: 12(2), P. 180 - 180

Published: Feb. 13, 2025

Artificial Intelligence (AI) is reshaping healthcare through advancements in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered tools are increasingly matching or exceeding specialist-level performance across multiple domains, paving the way for a new era of democratized access. These systems promise reduce disparities care delivery demographic, racial, socioeconomic boundaries by providing high-quality at scale. As result, advanced services can be affordable all populations, irrespective demographics, race, background. The democratization such AI cost care, optimize resource allocation, improve quality care. In contrast humans, potentially uncover complex relationships data from large set inputs generate evidence-based knowledge medicine. However, integrating into raises several ethical philosophical concerns, as bias, transparency, autonomy, responsibility, accountability. this study, we examine recent advances AI-enabled image analysis, current regulatory frameworks, emerging best practices integration. We analyze both technical challenges inherent deploying institutions, with particular attention privacy, algorithmic fairness, system transparency. Furthermore, propose practical solutions address key challenges, including scarcity, racial bias training datasets, limited model interpretability, systematic biases. Finally, outline conceptual algorithm responsible implementations identify promising future research development directions.

Language: Английский

Citations

1

Allergies to food and airborne allergens in children and adolescents: role of epigenetics in a changing environment DOI
Erik Melén, Gerard H. Koppelman, Ana M. Vicedo‐Cabrera

et al.

The Lancet Child & Adolescent Health, Journal Year: 2022, Volume and Issue: 6(11), P. 810 - 819

Published: Aug. 16, 2022

Language: Английский

Citations

33

Current state and prospects of artificial intelligence in allergy DOI Creative Commons
Merlijn van Breugel, Rudolf S.N. Fehrmann,

Marnix Bügel

et al.

Allergy, Journal Year: 2023, Volume and Issue: 78(10), P. 2623 - 2643

Published: Aug. 16, 2023

Abstract The field of medicine is witnessing an exponential growth interest in artificial intelligence (AI), which enables new research questions and the analysis larger types data. Nevertheless, applications that go beyond proof concepts deliver clinical value remain rare, especially allergy. This narrative review provides a fundamental understanding core AI critically discusses its limitations open challenges, such as data availability bias, along with potential directions to surmount them. We provide conceptual framework structure within this discuss forefront case examples. Most these machine learning allergy concern supervised unsupervised clustering, strong emphasis on diagnosis subtyping. A perspective shared guidelines for good practice guide readers applying it effectively safely, prospects advancement initiatives increase impact. anticipate can further deepen our knowledge disease mechanisms contribute precision

Language: Английский

Citations

19

Artificial Intelligence: A Snapshot of Its Application in Chronic Inflammatory and Autoimmune Skin Diseases DOI Creative Commons
Federica Li Pomi,

Vincenzo Papa,

Francesco Borgia

et al.

Life, Journal Year: 2024, Volume and Issue: 14(4), P. 516 - 516

Published: April 16, 2024

Immuno-correlated dermatological pathologies refer to skin disorders that are closely associated with immune system dysfunction or abnormal responses. Advancements in the field of artificial intelligence (AI) have shown promise enhancing diagnosis, management, and assessment immuno-correlated pathologies. This intersection dermatology immunology plays a pivotal role comprehending addressing complex involvement. The paper explores knowledge known so far evolution achievements AI diagnosis; discusses segmentation classification medical images; reviews existing challenges, immunological-related diseases. From our review, has emerged, especially analysis images for both diagnostic severity purposes. Furthermore, possibility predicting patients’ response therapies is emerging, order create tailored therapies.

Language: Английский

Citations

8

Bridging Health Disparities in the Data-Driven World of Artificial Intelligence: A Narrative Review DOI
Anastasia Murphy,

Kuan Bowen,

Isaam M El Naqa

et al.

Journal of Racial and Ethnic Health Disparities, Journal Year: 2024, Volume and Issue: unknown

Published: July 2, 2024

Language: Английский

Citations

7