Long COVID and older people

The Lancet Healthy Longevity, Journal Year: 2022, Volume and Issue: 3(12), P. e849 - e854

Published: Dec. 1, 2022

Long COVID is a poorly understood condition, with wide spectrum of effects on multiple body systems and variable presentation in different individuals. particular concern among older people (ie, aged 65 years or older), who are at greater risk than younger persisting symptoms associated COVID-19. In addition, COVID-19 might trigger exacerbate chronic conditions that occur commonly people, such as cardiovascular diseases, respiratory neurodegenerative conditions, functional decline. the disruptive for should not be underestimated; lockdowns other restrictions have reduced social interactions they also likely to lost spouse loved one during pandemic, which can contribute mental physical vaccination appears reduce long COVID, especially those living care facilities, remain up-to-date their vaccinations. Health-care staff consider differential diagnosis relevant rather assume increasing frailty, pursue early multidisciplinary assessment management symptoms. Addressing physical, psychological, sequelae will mitigate effect improve health quality life people.

Language: Английский

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Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities

JAMA Internal Medicine, Journal Year: 2022, Volume and Issue: 182(8), P. 859 - 859

Published: June 23, 2022

The administration of a fourth BNT162b2 COVID-19 vaccine dose was approved in Israel December 2021 for individuals 60 years or older who were vaccinated with third 4 months previously earlier to control the substantial surge SARS-CoV-2 Omicron variant. Nonetheless, association between receipt and protection against infection remains elusive.To determine SARS-CoV-2-related infections, hospitalizations, deaths during long-term care facility (LTCF) residents.This prospective cohort study conducted January 10 March 31, 2022 included LTCF residents older.Vaccination vs 3 doses that administered earlier.Cumulative incidences surge. follow-up initiated more than 7 days after dose, which matched initiation date those had received each facility. We obtained hazard ratios 95% confidence intervals from multivariable Cox regression models.The data 43 775 (mean [SD] age, 80.1 [9.4] years; 29 679 women [67.8%]) analyzed, whom 24 088 (55.0%) 19 687 (45.0%) (4 earlier), respectively. median time 73 (4-dose group: IQR, 6 days; 3-dose 56 days). More postvaccination detected among 4058 fourth-dose 4370 third-dose recipients (cumulative incidence, 17.6% 24.9%). corresponding hospitalizations mild-to-moderate COVID-19, severe illness, mortality 0.9% 2.8%, 0.5% 1.5%, 0.2% 0.5%, adjusted protections 34% (95% CI, 30%-37%), 64% 56%-71%), 67% 57%-75%) overall infection, respectively, 72% 57%-83%) related deaths.The results this suggest conferred high variant surge, but modest infection. These findings are relevant pandemic globally, especially population LTCFs.

Language: Английский

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Measures to Prevent and Control COVID-19 in Skilled Nursing Facilities

JAMA Health Forum, Journal Year: 2025, Volume and Issue: 6(1), P. e245175 - e245175

Published: Jan. 31, 2025

Importance Skilled nursing facilities (SNFs) experienced high mortality during the COVID-19 pandemic, leading them to adopt preventive measures counteract viral spread. A critical appraisal of these is essential support SNFs in managing future infectious disease outbreaks. Objective To perform a scoping review data and evidence on use effectiveness implemented from 2020 2024 prevent infection US. Evidence Review Two analyses were performed. First, an analysis federal SNF Database was conducted describe time trends incidence, deaths, testing, vaccination, treatment among residents staff, as well shortages staff personal protective equipment (PPE). Then, comprehensive literature search May 2023 April identify high-quality modifiable used residents. Both nonpharmacologic (facility characteristics, PPE, cohorting, isolation, visitation, staffing, testing) pharmacologic (vaccination, treatment) reviewed. Findings Nationwide indicated early infrequent persistent SNFs. Other measures, such visitor restrictions or ventilation modifications, widely adopted but there no available national quantify their effectiveness. These lacked studies verify In contrast, vaccination antiviral shown multiple studies. also showed associations between outcomes crowding, size, hours per networks, surveillance testing staff. Despite initial uptake, up-to-date status suboptimal 2022 2024. Only minority infected received treatment. Conclusions Relevance This found that although many US throughout few based clear Pharmacologic treatment, had more robust supporting efficacy than interventions. Using scarce resources questionable could distract known effective ones When possible, implementation efforts should be commensurate with demonstrated measures.

Language: Английский

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Learning from the covid-19 outbreaks in long-term care facilities: a systematic review

BMC Geriatrics, Journal Year: 2023, Volume and Issue: 23(1)

Published: Oct. 2, 2023

Abstract Background The COVID-19 pandemic has devastatingly affected Long-Term Care Facilities (LTCF), exposing aging people, staff members, and visitors. world learned through the lessons can be taken to adopt effective measures deal with outbreaks in LTCF. We aimed systematically review available evidence on effect of minimize risk transmission LTCs during since 2021. Methods search method was guided by preferred reporting items for systematic reviews (PRISMA) guideline synthesis without meta-analysis (SWiM) reviews. performed April 2023. Observational interventional studies from databases PubMed, Web Science, Scopus, Cochrane Systematic Reviews, CINAHL, Academic Search were reviewed. included conducted LTCF that quantitatively assess non-pharmacological cases COVID-19. Two authors independently reviewed titles inclusion, extracted data, undertook bias according pre-specified criteria. quality analyzed using Joanna Briggs Institute Critical Appraisal. Results Thirteen included, 8442 experiencing 598 thousand participants (residents members). Prevention control infection interventions grouped into three themes: strategic, tactical, operational measures. strategic reveal importance prevention as structural characteristics, namely size, new admissions, surveillance, architectural structure. At tactical level, lack personal long shifts is related COVID-19's spread. Operational a favorable preventing are sufficient. Personal protective equipment stock, correct mask use, signaling, social distancing, resident cohorting. Conclusions Operational, approaches may have spread LTCFs outbreaks. Given heterogeneous nature measures, performing not possible. Future research should use more robust study designs explore similar endemic situations comparable Trial registration protocol this registered PROSPERO (CRD42020214566).

Language: Английский

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Impact of the COVID-19 pandemic and corresponding control measures on long-term care facilities: a systematic review and meta-analysis

Age and Ageing, Journal Year: 2023, Volume and Issue: 52(1)

Published: Jan. 1, 2023

Abstract Background Long-term care facilities (LTCFs) were high-risk settings for COVID-19 outbreaks. Objective To assess the impacts of pandemic on LTCFs, including rates infection, hospitalisation, case fatality, and mortality, to determine association between control measures SARS-CoV-2 infection in residents staff. Method We conducted a systematic search six databases articles published December 2019 5 November 2021, performed meta-analyses subgroup analyses identify impact LTCFs rate. Results included 108 studies from 19 countries. These 1,902,044 255,498 staff 81,572 among whom 296,024 36,807 confirmed positive. The pooled rate was 32.63% (95%CI: 30.29 ~ 34.96%) residents, whereas it 10.33% 9.46 11.21%) In that cancelled visits, new patient admissions, communal dining group activities, vaccinations, lower than global reported residents’ hospitalisation be 29.09% 25.73 32.46%), with case-fatality 22.71% 21.31 24.11%) mortality 15.81% 14.32 17.30%). Significant publication biases observed rate, but not or residents. Conclusion would very high LTCF without appropriate measures. Cancelling restricting increasing vaccination significantly reduce rates.

Language: Английский

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COVID-19 and the elderly

Physiology International, Journal Year: 2022, Volume and Issue: 109(2), P. 177 - 185

Published: May 16, 2022

COVID-19 has become a great burden of the world in respect health care, social, and economical reason. Several million people died worldwide so far more mutants are generated spread. Older with co-morbidities frailty syndrome have significantly higher risk to get infection also serious disease process. Mortality is case geriatric patients. In this review we attempted summarize factors susceptibility for disease, what actions need be taken defending older patients special aspects clinical presentation including ophthalmic symptoms.

Language: Английский

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Lessons from COVID-19 in Taiwan's long-term care facilities: A narrative review

Journal of the Formosan Medical Association, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The coronavirus Disease 2019 (COVID-19) pandemic has disproportionately impacted long-term care facilities (LTCFs), revealing vulnerabilities due to residents' advanced age, comorbidities, and facility infrastructures. In Taiwan, the Central Epidemic Control Center implemented a range of strategies protect LTCF residents. These included early containment measures allow time for preparing pharmaceutical intervention, establishment infection prevention control guidelines, implementation comprehensive screening testing protocols, prioritization vaccination both residents staff, expansion national stockpile oral antiviral agents. Measures also addressed protective personal equipment shortages, staffing challenges, integration between social healthcare services, accessibility anti-viral All were made adjusted based on community prevalence, evolving knowledge about virus, balancing negative impacts multifaceted efforts effectively mitigated transmission, maintained essential supported demonstrating critical importance coordinated, adaptive in managing impact COVID-19 vulnerable populations LTCFs. By learning from pandemic, we can develop more effective resilient responses future epidemics LTCFs Taiwan.

Language: Английский

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Equipping residential aged care facilities for acute respiratory illness: The Western Sydney experience of improving outbreak management

Australasian Journal on Ageing, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

Abstract Objectives Acute respiratory illnesses have a disproportionate impact on older people, and especially those living in residential aged care facilities where transmission risks are heightened. Additionally, staff these been working under challenging conditions, often ill‐equipped terms of both training resources to successfully manage the outbreaks illnesses. This paper examines actions an Australian public health unit improve influenza outbreak management critiques outcomes through contemporary lens. Methods A naturalistic case study using critical thematic analysis was used Western Sydney Public Health Unit's work with their jurisdiction during 2014–2019. Results Key approach improving sustained engagement stakeholders, activities build capacity this setting, investment research inform ongoing action. mutually beneficial, as Unit became more attuned each other's needs challenges. Supporting facility difficult situations resulted timelier response improved management. Conclusions In Australia, Units important partners cumulative development responsiveness setting; particularly considering challenges posed by novel pathogens establishing evidence base for best practice future preparedness.

Language: Английский

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Disparities in anxiety and related factors among Chinese older adults across different aged-care models: a comparison of two cross-sectional studies

BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 21, 2025

Anxiety disorders in older adults have become a prominent public health problem due to their concomitant chronic conditions, reduced quality of life and even death. However, fewer studies been conducted on differences anxiety among individuals different aged-care models, the interactive relationship between influencing factors remains unclear. The study aimed examine disparities prevalence community-dwelling institutionalized related factors. Data were collected from Anhui Healthy Longevity Survey (AHLS) Elderly Caring Social Organizations (AECSOS). demographic variables, lifestyle health-related variables 6968 used for analysis. symptoms evaluated using Generalized Disorder Assessment Scale (GAD-7). Binary logistic regression models Classification Regression Tree model (CART) utilized variables. 24.3% 16.7% adults, respectively. Several including age, gender, residence, education, income level, live alone, number diseases showed linkage with adults. For source income, exhibited significant association anxiety. We noted effect, suggesting that female an level less than 6500 RMB per year reported disease comorbidities had highest likelihood anxiety, sources such as pension, subsidy, family providing, resident rural areas greatest risk experiencing This has brought light higher compared Targeted interventions are, therefore emphasized address negative impact populations at risk.

Language: Английский

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Non-Pharmaceutical Interventions on COVID-19 in Workers and Residents of Nursing Homes in Geneva: A Mixed Qualitative and Quantitative Study

Epidemiologia, Journal Year: 2025, Volume and Issue: 6(1), P. 14 - 14

Published: March 11, 2025

The objective of this study was to examine the impact varying levels non-pharmaceutical interventions (NPIs) on COVID-19 transmission in nursing homes during first wave pandemic. Background/Objectives: primary aim involved exploring qualitative insights from staff and management regarding implementation NPIs. secondary determine cumulative incidence PCR-confirmed cases among residents. Incident rate ratios (IRRs) were calculated NPI restrictiveness. Methods: We used a mixed methodology identify factors that might have affected expansion canton Geneva, Switzerland. For component, we interviewed Attending Physicians and/or Director each home. In quantitative incident for infection between three COVID-19-related measures taken these homes, their resident population. This conducted 12 located Switzerland, 1 March 2020, June 2020. Results: Most mandated NPIs residents COVID-19. found an equal distribution maximally (n = 4), moderately minimally 4) restrictive home workers extent implemented not shown be significantly associated with (maximally IRR 3.90, 95%CI 0.82–45.54, p 0.184; 3.55, 0.75–41.42, 0.212; reference). Conclusions: Nursing our showed high variability which NPIs, what extent, they implemented, no significant relationship restrictiveness suggests other influence settings. Future research should explore additional determinants balance strict overall well-being

Language: Английский

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