JMIR Formative Research, Journal Year: 2024, Volume and Issue: 9, P. e59154 - e59154

Published: Nov. 5, 2024

There is increasing interest in the development of scalable digital mental health interventions for perinatal populations to increase accessibility. Mobile behavioral activation (BA) efficacious treatment depression; however, effect comorbid anxiety and depression (CAD) on symptom trajectories remains underexplored. This important given that at least 10% women period experience CAD. We assessed whether there were differences pregnant participants with CAD as compared those only (ie, major depressive disorder [MDD]) during intervention a BA mobile gaming app. Pregnant adults either (n=10) or MDD (n=7) used app 10 weeks completed biweekly severity questionnaires anxiety. baseline diagnoses associated differential across study mixed effects longitudinal models. When controlling symptoms, results revealed significant interaction between diagnosis quadratic component week (β=.18, SE 0.07; t62=2.61; P=.01), revealing tendency group initially then decrease an accelerated rate, whereas symptoms relatively stable time. was linear time (β=-.39, 0.11; t68=-3.51; P=.001), showing declined steadily both groups. (β=-8.53, 3.93; t13=-2.17; P=.05), suggesting had higher follow-up when holding other predictors constant. The beneficial reducing individuals different comorbidity profiles. With respect trajectories, more variability. may be especially effective among CAD, it encourages in-the-moment ecologically relevant exposure anxiety-provoking stimuli. Despite no difference did not have reduction their period, some Findings point opportunities augmentation apps effectively target symptoms. Overall, findings suggest value considering comorbidities individual variations developing populations.

Language: Английский