
Biomedicines, Journal Year: 2024, Volume and Issue: 12(9), P. 2129 - 2129
Published: Sept. 19, 2024
Adipose tissue was previously regarded as a dormant organ for lipid storage until the identification of adiponectin and leptin in early 1990s. This revelation unveiled dynamic endocrine function adipose tissue, which has expanded further. emerged recent decades multifunctional that plays significant role energy metabolism homeostasis. Currently, it is evident primarily performs its by secreting diverse array signaling molecules known adipokines. Apart from their pivotal expenditure regulation, these adipokines exert influence over multitude biological processes, including but not limited to inflammation, thermoregulation, immune response, vascular function, insulin sensitivity. Adipokines are regulating numerous processes within facilitating communication between various organs, brain, gut, pancreas, endothelial cells, liver, muscle, more. Dysregulated have been implicated several metabolic diseases, like obesity diabetes, well cardiovascular diseases. In this article, we attempted describe significance developing diseases highlight crosstalk tissues other organs.
Language: Английский