Chinese herbal medicine-derived extracellular vesicles as novel biotherapeutic tools: present and future DOI Creative Commons
Jinying Zhang, Shuo Tian, Lin Guo

et al.

Journal of Translational Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Nov. 25, 2024

Extracellular vesicles (EVs) are phospholipid bilayer-enclosed biological particles that secreted by almost all living cells including animals, plants, and microorganisms. Chinese herbal medicines (CHM) have a long history of using plant-based remedies to treat prevent human diseases. medicine-derived extracellular vesicle (CHMEV) generic term refers nanoscale membrane structures isolated from medicinal plants such as ginseng, ginger, Panax notoginseng. In recent years, CHMEVs garnered substantial attention novel class functional components due their high bioavailability, safety, easy accessibility, diverse therapeutic effects, indicating great potential for development new dosage form CHM. Research on in traditional medicine (TCM) has become prominent area interest, opening avenues further exploration into the effects mechanisms Nonetheless, an emerging field, there is much unknown about these vesicles, current research remains inconsistent. The review comprehensively summarizes biogenesis, isolation methods, physical, biochemical characterizations CHMEVs. Additionally, we highlight biomedical applications agents drug delivery carriers, anti-inflammatory, anticancer, regenerative, antiaging activities. Finally, propose challenges future perspectives. By summarizing existing literature, aim offer valuable clues inspiration CHMEV research, thereby facilitating standardization treatment diseases discovery.

Language: Английский

Applying “Hand-as-Foot” method in teaching bronchoscopy DOI Creative Commons

Hongxia Gu

Asian Journal of Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Chinese herbal medicine-derived extracellular vesicles as novel biotherapeutic tools: present and future DOI Creative Commons
Jinying Zhang, Shuo Tian, Lin Guo

et al.

Journal of Translational Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Nov. 25, 2024

Extracellular vesicles (EVs) are phospholipid bilayer-enclosed biological particles that secreted by almost all living cells including animals, plants, and microorganisms. Chinese herbal medicines (CHM) have a long history of using plant-based remedies to treat prevent human diseases. medicine-derived extracellular vesicle (CHMEV) generic term refers nanoscale membrane structures isolated from medicinal plants such as ginseng, ginger, Panax notoginseng. In recent years, CHMEVs garnered substantial attention novel class functional components due their high bioavailability, safety, easy accessibility, diverse therapeutic effects, indicating great potential for development new dosage form CHM. Research on in traditional medicine (TCM) has become prominent area interest, opening avenues further exploration into the effects mechanisms Nonetheless, an emerging field, there is much unknown about these vesicles, current research remains inconsistent. The review comprehensively summarizes biogenesis, isolation methods, physical, biochemical characterizations CHMEVs. Additionally, we highlight biomedical applications agents drug delivery carriers, anti-inflammatory, anticancer, regenerative, antiaging activities. Finally, propose challenges future perspectives. By summarizing existing literature, aim offer valuable clues inspiration CHMEV research, thereby facilitating standardization treatment diseases discovery.

Language: Английский

Citations

1