The Impact of Soybean Genotypes on Rhizosphere Microbial Dynamics and Nodulation Efficiency

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 2878 - 2878

Published: March 21, 2025

Rhizosphere microbiome exerts a significant role in plant health, influencing nutrient availability, disease resistance, and overall growth. Establishing robust efficient nodulation process is essential for optimal nitrogen fixation legumes like soybeans. Different soybean genotypes exhibit variations their rhizosphere microbiome, potentially impacting through nodulation. However, detailed understanding of how specific influence microbial communities patterns remains limited. Our study aims to investigate the relationship between abundance growth four genotypes. We evaluated parameters, including biomass, leaf area, stomatal conductance, identified genotypic differences Specifically, PI 458505 603490 exhibited high levels nodulation, while 605839A 548400 displayed low 16S rRNA gene amplicon sequencing revealed diverse bacterial rhizosphere, with Proteobacteria as dominant phylum. High-nodulation harbored more enriched Actinobacteria Acidobacteriota, low-nodulation showed higher abundances Firmicutes Planctomycetota. Alpha beta diversity analyses confirmed distinct community structures high- groups. findings suggest that significantly influences highlighting potential genotype-driven strategies enhance plant-microbe interactions improve productivity.

Language: Английский

Genotype-specific rhizosphere microbiome assembly and its impact on soybean (Glycine max (L.) Merri.) yield traits

Frontiers in Sustainable Food Systems, Journal Year: 2025, Volume and Issue: 9

Published: April 15, 2025

Introduction The rhizosphere microbiome plays a critical role in plant growth and productivity. However, the genotype-specific dynamics functional influence of these microbial communities on soybean ( Glycine max (L.) Merri.) yield traits remain underexplored. This study investigated composition implications conventional genetically modified (GM) varieties under field conditions. Methods A comparative analysis was conducted associated with H0269 transgenic Z1510 M579 at seedling flowering stages. High-throughput sequencing 16S rDNA ITS regions used to profile bacterial fungal communities. Alpha beta diversity metrics were assessed, correlation analyses performed identify taxa linked traits. Results Distinct community structures observed across genotypes Proteobacteria , Acidobacteriota Actinobacteria dominant phyla, while Ascomycota predominated among fungi. Genotype-specific differences evident, exhibiting highest alpha diversity. Beta revealed significant shifts between stages, particularly for Correlation identified 15 13 species significantly such as density, grain weight, theoretical yield. Discussion results highlight genotype-dependent recruitment microorganisms their potential impact GM selectively enriched beneficial microbes that may enhance nutrient uptake, stress tolerance, disease resistance. These findings provide valuable insights into plant-microbe interactions, paving way developing inoculants breeding strategies optimize sustainable agriculture.

Language: Английский

Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy

Molecular Cancer, Journal Year: 2024, Volume and Issue: 23(1)

Published: Dec. 19, 2024

Oral squamous cell carcinoma (OSCC) is a prevalent oral malignancy, which poses significant health risks with high mortality rate. Regulatory T cells (Tregs), characterized by their immunosuppressive capabilities, are intricately linked to OSCC progression and patient outcomes. The metabolic reprogramming of Tregs within the tumor microenvironment (TME) underpins function, key pathways such as tryptophan-kynurenine-aryl hydrocarbon receptor, PI3K-Akt-mTOR nucleotide metabolism significantly contributing suppressive activities. Targeting these offers novel therapeutic approach reduce Treg-mediated immunosuppression enhance anti-tumor responses. This review explores dependencies that sustain Treg function in OSCC, highlighting adaptations glycolysis, fatty acid oxidation, amino signaling pathway enable thrive challenging conditions TME. Additionally, discusses influence microbiome on evaluates potential strategies targeting pathways. Despite promising interventions, challenges selectivity, toxicity, heterogeneity, resistance mechanisms remain. concludes perspectives personalized medicine integrative approaches, emphasizing need for continued research translate findings into effective clinical applications treatment.

Language: Английский