Lupus,
Journal Year:
2023,
Volume and Issue:
32(14), P. 1686 - 1688
Published: Nov. 9, 2023
Cranial
neuropathy
is
a
rare
presentation
in
juvenile
(j)
SLE
and
being
multiple
even
rarer.
We
describe
here
an
adolescent
girl
presenting
with
polyneuritis
cranialis
(PNC)
as
initial
of
which
had
not
been
reported
before
literature.
She
presented
symptoms
suggestive
bilateral
abducent
hypoglossal
nerve
conduction
studies
showing
partial
axonal
left
facial
accessory
nerves,
6
weeks
after
common
cold.
The
condition
was
associated
any
other
neurological
or
systemic
manifestations
nor
features
Sjogren's
syndrome.
Her
responded
well
to
pulsed
methylprednisolone
therapy
plasma
exchange.
After
exclusion
the
causes
owing
positive
ANA
results
mild
proteinuria,
renal
biopsy
taken
revealed
histopathological
class
III
lupus
nephritis
for
mycophenolate
mofetil
started
at
1200
mg
per
m2.
Our
case
highlights
importance
considering
collagen
disorders
including
differential
diagnosis
children
PNC
order
allow
adequate
management
proper
follow-up.
Current Opinion in Rheumatology,
Journal Year:
2024,
Volume and Issue:
36(5), P. 315 - 321
Published: May 15, 2024
This
narrative
review
offers
an
update
of
the
most
important
recent
articles
published
in
previous
year
childhood-onset
systemic
lupus
erythematosus
(cSLE),
focusing
on
care
and
management.
Pediatric Rheumatology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Oct. 31, 2024
Hemophagocytic
lymphohistiocytosis
(HLH)
is
characterized
by
immune
dysregulation
that
results
in
an
uncontrolled
hyperinflammatory
state.
HLH
classified
into
two
main
categories:
primary
(familial)
and
secondary
(acquired)
HLH.
Secondary
can
result
from
various
underlying,
including
infection-associated
hemophagocytic
syndrome
(IAHS)
macrophage
activation
(MAS)
associated
with
rheumatologic
disorders,
among
others.
Epstein-Barr
virus
(EBV)
often
causes
IAHS,
but
central
nervous
system
(CNS)
involvement
rare
systemic
lupus
erythematosus
(SLE)
patients.
We
report
a
case
of
EBV
encephalitis
patient
childhood-onset
SLE.
Brazilian Journal of Implantology and Health Sciences,
Journal Year:
2024,
Volume and Issue:
6(4), P. 180 - 189
Published: April 2, 2024
Este
artigo
tem
por
objetivo
explorar
a
literatura
médica
vigente
acerca
das
manifestações
psicóticas
e
sintomas
neuropsiquiátricos
relacionados
ao
Lúpus
Eritematoso
Sistêmico
(LES).
Foram
utilizadas
as
bases
de
dados:
PubMed,
Scielo,
Uptodate,
ScienceDirect
Google
Acadêmico.
Após
seleção,
os
artigos
foram
submetidos
critérios
inclusão
exclusão
para
produção
revisão
sistemática.
Conclui-se
que
neuropsiquiátricas
no
LES
trazem
disfunções
significativas
à
qualidade
vida,
funcionalidade
estado
geral
saúde
dos
pacientes.
Case Reports in Rheumatology,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
We
reported
a
10-year-old
girl
who
had
an
atypical
demyelinating
disease
as
the
presentation
of
her
neuropsychiatric
lupus.
The
patient
4-year
history
systemic
lupus
erythematosus
which
been
on
remission
until
she
presented
with
fever
and
headache
at
age
10
years.
Physical
examination
showed
meningism.
Extensive
microbiological
workup
for
infective
meningitis
was
unrevealing.
There
radiographic
finding
extensive
white
matter
hyperintensity
magnetic
resonance
imaging
(MRI)
brain.
At
initial
stage
our
case,
it
difficult
to
differentiate
between
infection
central
nervous
system
manifestation
lupus,
course
intravenous
immunoglobulin
given
empirically
instead
high-dose
corticosteroid
while
awaiting
results.
subsided
shortly
after
commencement
without
use
pulse
corticosteroid.
After
active
neurological
symptoms
remitted,
total
six
monthly
doses
2
g/kg/cycle
biweekly
cyclophosphamide
500
mg/m
Lupus,
Journal Year:
2023,
Volume and Issue:
32(14), P. 1686 - 1688
Published: Nov. 9, 2023
Cranial
neuropathy
is
a
rare
presentation
in
juvenile
(j)
SLE
and
being
multiple
even
rarer.
We
describe
here
an
adolescent
girl
presenting
with
polyneuritis
cranialis
(PNC)
as
initial
of
which
had
not
been
reported
before
literature.
She
presented
symptoms
suggestive
bilateral
abducent
hypoglossal
nerve
conduction
studies
showing
partial
axonal
left
facial
accessory
nerves,
6
weeks
after
common
cold.
The
condition
was
associated
any
other
neurological
or
systemic
manifestations
nor
features
Sjogren's
syndrome.
Her
responded
well
to
pulsed
methylprednisolone
therapy
plasma
exchange.
After
exclusion
the
causes
owing
positive
ANA
results
mild
proteinuria,
renal
biopsy
taken
revealed
histopathological
class
III
lupus
nephritis
for
mycophenolate
mofetil
started
at
1200
mg
per
m2.
Our
case
highlights
importance
considering
collagen
disorders
including
differential
diagnosis
children
PNC
order
allow
adequate
management
proper
follow-up.
