Berry Fruit Extracts as Topical Cosmeceuticals for Skin Health Applications: A Systematic Review DOI Creative Commons
Filipe Silveira Azevedo,

Allan Rodrigues Pires,

Mary Ann Lila

et al.

Cosmetics, Journal Year: 2025, Volume and Issue: 12(3), P. 87 - 87

Published: April 23, 2025

Berries are a popular source of natural bioactive compounds with distinctive aspects and sensory attributes. In this review, the term “berry” refers to generally round, small, colorful, juicy fruits English common names ending in “berry”. They have high phenolic content, which has been linked their health-relevant properties. To gather information on potential berries for treating skin inflammatory diseases, systematic review was conducted following PRISMA guidelines (PROSPERO registration number CRD 42024549567), based studies from PubMed, Scopus, Web Science, Embase. It focused preclinical murine model studies, bias methodological quality assessed using SYRCLE’s RoB tool. Studies showed evidence that anti-inflammatory antioxidant properties due like anthocyanins, cyanidins, polyphenols, catechins. Berry exposure reduced oxidative stress markers, such as malondialdehyde, carbonylated proteins, nitric oxide, 8-OHdG, pyrimidine dimers. This reduction associated NF-κB COX-2 pathway downregulation, lower IL-6, IL-1β, TNF-α, MAPK, increased IL-10. Morphological outcomes included collagen, elastin, glycosaminoglycans, proteoglycans metalloproteinases. Bias analysis revealed low risk, suggesting reliable studies. treatments improved wound healing extracellular matrix (ECM) production, supporting pharmaceutical topical formulation.

Language: Английский

Berry Fruit Extracts as Topical Cosmeceuticals for Skin Health Applications: A Systematic Review DOI Creative Commons
Filipe Silveira Azevedo,

Allan Rodrigues Pires,

Mary Ann Lila

et al.

Cosmetics, Journal Year: 2025, Volume and Issue: 12(3), P. 87 - 87

Published: April 23, 2025

Berries are a popular source of natural bioactive compounds with distinctive aspects and sensory attributes. In this review, the term “berry” refers to generally round, small, colorful, juicy fruits English common names ending in “berry”. They have high phenolic content, which has been linked their health-relevant properties. To gather information on potential berries for treating skin inflammatory diseases, systematic review was conducted following PRISMA guidelines (PROSPERO registration number CRD 42024549567), based studies from PubMed, Scopus, Web Science, Embase. It focused preclinical murine model studies, bias methodological quality assessed using SYRCLE’s RoB tool. Studies showed evidence that anti-inflammatory antioxidant properties due like anthocyanins, cyanidins, polyphenols, catechins. Berry exposure reduced oxidative stress markers, such as malondialdehyde, carbonylated proteins, nitric oxide, 8-OHdG, pyrimidine dimers. This reduction associated NF-κB COX-2 pathway downregulation, lower IL-6, IL-1β, TNF-α, MAPK, increased IL-10. Morphological outcomes included collagen, elastin, glycosaminoglycans, proteoglycans metalloproteinases. Bias analysis revealed low risk, suggesting reliable studies. treatments improved wound healing extracellular matrix (ECM) production, supporting pharmaceutical topical formulation.

Language: Английский

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