A bimetallic PdCu–Fe3O4catalyst with an optimal d-band centre for selectiveN-methylation of aromatic amines with methanol DOI
Jin Hee Cho, Yoonhoo Ha, Ahra Cho

et al.

Catalysis Science & Technology, Journal Year: 2022, Volume and Issue: 12(11), P. 3524 - 3533

Published: Jan. 1, 2022

Highly efficient and selective N -methylation of aniline with methanol is possible Pd 1 Cu 0.6 –Fe 3 O 4 nanoparticle catalyst.

Language: Английский

Emerging breakthroughs in covalent triazine frameworks: From fundamentals towards photocatalytic water splitting and challenges DOI
Asif Hayat,

Hamid Ali,

Zeeshan Ajmal

et al.

Progress in Materials Science, Journal Year: 2024, Volume and Issue: 147, P. 101352 - 101352

Published: Aug. 14, 2024

Language: Английский

Citations

20
Iridium supported on porous polypyridine-oxadiazole as high-activity and recyclable catalyst for the borrowing hydrogen reaction DOI
Jiahao Li,

Anruo Mao,

Wei Yao

et al.

Green Chemistry, Journal Year: 2022, Volume and Issue: 24(6), P. 2602 - 2612

Published: Jan. 1, 2022

Porous polypyridine-oxadiazole supported iridium catalysts (PPO-Ir) revealed high catalytic activity for the reaction of dimethyl-6-aminouracil (including 1,3-dimethylbarbituric acid, 2-aminobenzylamine) with alcohols.

Language: Английский

Citations

53
Upgrading Ethanol to n-Butanol in the Presence of Carbonate Catalyzed by a Cp*Ir Complex Bearing a Functional 2,2′-Carbonylbibenzimidazole Ligand DOI
Xiangchao Xu, Jin Zhang, Beixuan Dong

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 63(8), P. 3843 - 3849

Published: Feb. 14, 2024

Upgrading ethanol to n-butanol as biofuels is an important topic for sustainable chemistry. Herein, a Cp*Ir complex bearing functional 2,2′-carbonylbibenzimidazole ligand [Cp*Ir(2,2′-COBiBzImH2)Cl][Cl] was designed and synthesized. In the presence of catalyst (0.1 mol %) Cs2CO3 (6 %), highest yield updated up 37% with 80% selectivity. NH units in are crucially catalytic activity iridium complex.

Language: Английский

Citations

10
Manganese‐Catalyzed Mono‐N‐Methylation of Aliphatic Primary Amines without the Requirement of External High‐Hydrogen Pressure DOI

Jiale Ji,

Yinghao Huo,

Zhaowen Dai

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(13)

Published: Feb. 1, 2024

Abstract The synthesis of mono‐ N ‐methylated aliphatic primary amines has traditionally been challenging, requiring noble metal catalysts and high‐pressure H 2 for achieving satisfactory yields selectivity. Herein, we developed an approach the selective coupling methanol amines, without hydrogen, using a manganese‐based catalyst. Remarkably, up to 98 % with broad substrate scope were achieved at low catalyst loadings. Notably, due weak base‐catalyzed alcoholysis formamide intermediates, our novel protocol not only obviates addition but also prevents side secondary ‐methylation, supported by control experiments density functional theory calculations.

Language: Английский

Citations

9
A Guide for Mono‐Selective N‐Methylation, N‐Ethylation, and N‐n‐Propylation of Primary Amines, Amides, and Sulfonamides and Their Applicability in Late‐Stage Modification DOI Creative Commons
Johanna Templ, Michael Schnürch

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(26)

Published: Feb. 14, 2024

Abstract This review provides a comprehensive overview of mono‐alkylation methodologies targeting crucial nitrogen moieties – amines, amides, and sulfonamides found in organic building blocks pharmaceuticals. Emphasizing the intersection chemical precision with drug discovery, central challenge addressed is achieving one‐pot mono‐selective short‐chain N‐alkylations (methylations, ethylations, n ‐propylations), preventing undesired overalkylation. Additionally, sustainable, safe, benign alternatives to traditional alkylating agents, including alcohols, carbon dioxide, carboxylic acids, nitriles, alkyl phosphates, quaternary ammonium salts, carbonates, are explored. review, categorized by nature agent, aids researchers selecting suitable methods for N‐alkylation.

Language: Английский

Citations

6
Cp*Ir complex bearing a flexible bridging and functional 2,2′-methylenebibenzimidazole ligand as an auto-tandem catalyst for the synthesis of N-methyl tertiary amines from imines via transfer hydrogenation/N-methylation with methanol DOI
Xiaozhong Chen, Yao Ai, Peng Liu

et al.

Journal of Catalysis, Journal Year: 2021, Volume and Issue: 402, P. 325 - 334

Published: Aug. 26, 2021

Language: Английский

Citations

36
Structurally Well-Defined PC(sp3)P Osmium Pincer Catalysts for Methylation of Alcohols, Indoles, Phenols, and Sulfonamides Using Methanol as a C1 Source DOI Creative Commons
Nandita Biswas, Dmitri Gelman

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(3), P. 1629 - 1638

Published: Jan. 17, 2024

Recent findings show pincer catalysts of osmium superior in a broad spectrum synthetically valuable transformations. This article reports structurally well-defined Os(II)PCsp3P complexes stabilized by functional dibenzobarrelene-based ligand. We describe their organometallic and catalytic properties the hydride transfer reactions. demonstrate that center, covalently locked within 3-dimensional ligand pocket, exhibits strictly predictable coordination behavior redox rigidity while remaining catalytically active owing to potential cooperation with proximate side arm. The described were found as mild selective methylation alcohols, indoles, phenols, sulfonamides using methanol C1 source.

Language: Английский

Citations

5
Recent Development in Synthesis of N‐Methylamines with Amines and Methanol DOI
Xiaogang Yu, Xinjiang Cui, Huanwang Jing

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: 16(16)

Published: March 23, 2024

Abstract The N‐methylation reaction of amines with methanol via the borrowing‐hydrogen strategy is an important method for construction C−N bonds. Compared other C1 sources, such as toxic formaldehyde or expensive formic acid, more suitable reactions due to its eco‐friendliness and low price. Using this strategy, various types N‐methylated products, including biological pharmaceutical molecules have been prepared. Here, we present a thorough survey decades articles showing current developments in methanol. We discuss homogenous, heterogenous light‐driven catalytic systems both N,N‐dimethylation reactions. This review presents shortcomings provides future development progress

Language: Английский

Citations

5
Poly(2,2′-Bibenzimidazole)–Supported Iridium Complex: A Recyclable Metal–Polymer Ligand Bifunctional Catalyst for the N-Methylation of Amines with Methanol DOI
Beixuan Dong, Xingliang Wu,

Lu Shen

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 63(32), P. 15072 - 15080

Published: July 27, 2024

The design and development of new types catalysts is one the most important topics for modern chemistry. Herein, a polymer-supported iridium complex Cp*Ir@Poly(2,2'-BiBzIm) was designed synthesized by coordinative immobilization [Cp*IrCl

Language: Английский

Citations

4
Porous cross-linked polymer copper and iridium catalyzed the synthesis of quinoxalines and functionalized ketones under solvent-free conditions DOI
Jiahao Li,

Minyi Yu,

Zheng‐Chao Duan

et al.

Materials Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 5(21), P. 7861 - 7872

Published: Jan. 1, 2021

Two innovative porous cross-linked polymers (PCP–BTA–Ir and PCP–BTA–Cu) exhibited high catalytic activity towards the synthesis quinoxalines.

Language: Английский

Citations

27