Transition-Metal-Catalyzed C(sp3)–H Alkylation of Methyl Heteroarenes with Alcohols DOI Open Access
Bin Guo,

Jing Zhang,

Lin He

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(12), P. 881 - 881

Published: Dec. 3, 2024

Transition-metal-catalyzed C(sp3)-H bond functionalization is a useful transformation for the construction of C–C bonds. A versatile and easy-to-perform protocol in this respect C-alkylation methyl heteroarenes with alcohols using auto-transfer hydrogenative (ATH) reactions. Various transition metal catalysts based on Ir, Pt, Ru, Ni, Co, Fe Mn have been employed chain-elongated alkyl-substituted heterocyclic compounds chemistry. Water only byproduct starting are less toxic, readily available, more easily handled atom-economical substrates than their halogen counterparts. This review details recent advances synthetic methodology, describing scope, reaction mechanism, chemo-selectivity applications.

Language: Английский

NNN-Ru complexes catalyzed β-methylation of alcohols using methanol via borrowing hydrogen approach DOI

Mengxuan Bai,

Ziying Zhong, Zhiqiang Hao

et al.

Journal of Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 116026 - 116026

Published: Feb. 1, 2025

Language: Английский

Citations

0
Heterogeneous Mn@CeO2 Catalyst for α-Alkylation of Ketones with Alcohols via Hydrogen-Borrowing Strategy DOI Creative Commons

Rajagopal Swaathy,

S. Karthikeyan

ACS Omega, Journal Year: 2025, Volume and Issue: 10(9), P. 9649 - 9660

Published: Feb. 24, 2025

Construction of a C-C bond via alkylation ketones with alcohol as the alkylating source by employing hydrogen-borrowing strategy is attracting significant attention and highly appealing due to its simplicity, cost-effectiveness, environmental benefits, fact that water only byproduct. The development heterogeneous catalysts based on nonprecious base metals progressing rapidly. Our newly disclosed manganese-doped cerium oxide nanocomposite (10 wt % Mn@CeO2) stands out cost-efficient air-stable catalyst, synthesized through straightforward coprecipitation method employed for α-alkylation primary alcohols strategy. X-ray diffraction (XRD) analysis confirms high crystallinity CeO2, while field emission scanning electron microscopy (FE-SEM) high-resolution transmission (HR-TEM) images reveal MnO2 nanoparticles, measuring 19 nm in size, uniformly decorated rod-shaped CeO2 which have size 33 nm. photoelectron spectroscopy (XPS) uncovers presence Mn4+ species embedded nanorods. Electron paramagnetic resonance (EPR) further indicates surface defects contribute impressive catalytic yield, ranges from 70 98% α-alkylated ketones. Thermogravimetric (TGA) demonstrates remarkable thermal stability maintaining up 800 °C. Additionally, inductively coupled plasma mass spectrometry (ICP-MS) no leaching Mn ions, emphasizing heterogeneity catalyst. Remarkably, 10 Mn@CeO2 recycled six cycles loss activity. This study underscores synergistic effect between metal redox pair key exceptional activity reactions, making promising catalyst sustainable efficient formation.

Language: Английский

Citations

0
Construction of effective and recyclable non-precious metal coordination polymers and their multiple applications in water DOI
Jiahao Li,

Bin Pan,

Anruo Mao

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 111165 - 111165

Published: April 1, 2025

Language: Английский

Citations

0
Transition metal-catalyzed olefination of alkyl heteroarenes with alcohols DOI
Bin Guo, Jing Zhang,

Dan Chen

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 168, P. 134306 - 134306

Published: Oct. 18, 2024

Language: Английский

Citations

3
Transition-Metal-Catalyzed C(sp3)–H Alkylation of Methyl Heteroarenes with Alcohols DOI Open Access
Bin Guo,

Jing Zhang,

Lin He

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(12), P. 881 - 881

Published: Dec. 3, 2024

Transition-metal-catalyzed C(sp3)-H bond functionalization is a useful transformation for the construction of C–C bonds. A versatile and easy-to-perform protocol in this respect C-alkylation methyl heteroarenes with alcohols using auto-transfer hydrogenative (ATH) reactions. Various transition metal catalysts based on Ir, Pt, Ru, Ni, Co, Fe Mn have been employed chain-elongated alkyl-substituted heterocyclic compounds chemistry. Water only byproduct starting are less toxic, readily available, more easily handled atom-economical substrates than their halogen counterparts. This review details recent advances synthetic methodology, describing scope, reaction mechanism, chemo-selectivity applications.

Language: Английский

Citations

1