Heart failure with preserved ejection fraction and atrial fibrillation: epidemiology, pathophysiology, and diagnosis interplay
Heart Failure Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
Language: Английский
Atrial Functional Mitral Regurgitation: Definition, Mechanisms, and Treatment Perspectives
Current Cardiology Reports,
Journal Year:
2025,
Volume and Issue:
27(1)
Published: Jan. 11, 2025
Language: Английский
The interaction between atrial fibrillation and mitral regurgitation: Insights from the CABANA randomized clinical trial
European Journal of Heart Failure,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 21, 2025
Abstract
Aims
Atrial
fibrillation
(AF)
and
mitral
regurgitation
(MR)
frequently
coexist.
While
catheter
ablation
is
a
key
rhythm‐control
strategy
in
AF,
its
impact
on
MR
severity
remains
uncertain.
This
study
evaluates
the
effects
of
AF
recurrence,
functional
status,
progression
patients
with
baseline
MR.
Methods
results
sub‐analysis
included
1423
(65%
overall
CABANA
cohort)
available
echocardiography.
Participants
were
randomized
to
or
pharmacological
therapy.
The
primary
endpoint
was
composite
all‐cause
mortality
cardiovascular
hospitalization.
Secondary
endpoints
changes
severity,
status.
At
baseline,
722
(52%)
had
MR,
including
582
mild
140
≥moderate
characteristics
suggestive
an
atrial
mechanism.
Catheter
significantly
reduced
recurrence
compared
therapy
(odds
ratio
[OR]
0.56,
95%
confidence
interval
[CI]
0.50–0.62,
p
<
0.001).
presence
absence
did
not
interact
randomization
terms
neutral
effect
hospitalization
(
for
interaction
=
0.115).
Baseline
increased
risk
(OR
1.46,
CI
1.40–1.74,
However,
benefit
status
greater
those
without
Follow‐up
echocardiography
n
248)
showed
reduction
group
versus
drug
0.040).
Conclusion
superior
rhythm
control
may
reduce
over
time.
These
findings
highlight
ablation's
potential
structural
symptomatic
benefits,
pending
specifically
designed
clinical
trials.
Language: Английский
The Inextricable Link Between Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction
JACC Heart Failure,
Journal Year:
2025,
Volume and Issue:
13(5), P. 795 - 797
Published: May 1, 2025
Language: Английский
Heart Failure Risk Assessment Using Biomarkers in Patients With Atrial Fibrillation
Journal of the American College of Cardiology,
Journal Year:
2024,
Volume and Issue:
84(16), P. 1528 - 1540
Published: Sept. 2, 2024
Language: Английский
Novel Method for Risk Stratification of Major Adverse Clinical Events Using Pre- and Post-Ablation Left Atrial Volume Index in Patients With Persistent Atrial Fibrillation
Circulation Reports,
Journal Year:
2024,
Volume and Issue:
6(10), P. 415 - 423
Published: Sept. 6, 2024
The
relationship
between
changes
in
the
left
atrial
volume
index
(LAVI)
post-catheter
ablation
(CA)
and
long-term
prognostic
events
patients
with
persistent
fibrillation
(AF)
remains
unclear.
We
evaluated
incidence
of
major
adverse
clinical
(MACE),
including
all-cause
death,
unplanned
heart
failure
hospitalization,
cardiovascular
hospitalization
using
pre-
post-CA
LAVI.
Language: Английский