
Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12
Published: Feb. 20, 2025
Adherence to the Planetary Health Diet Index (PHDI) has been shown benefit both individual health and planet. However, its impact on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) remains unclear. This study aimed investigate relationship between PHDI adherence MASLD risk. We analyzed a cohort of 15,865 adults (aged ≥18 years) using data from National Nutrition Examination Survey (NHANES, 2005-2018). The was derived 24-h dietary assessments comprised scores 15 food groups. Multivariate logistic regression used association MASLD, while restricted cubic spline (RCS) threshold analysis were employed explore potential non-linear relationship. Subgroup analyses conducted assess influence various demographic clinical characteristics observed associations. Mediation performed evaluate indirect effect weighted quantile sum (WQS) nutrients MASLD. Among cohort, 6,125 individuals diagnosed with revealed that higher quintile significantly associated reduced risk in fully adjusted model (OR = 0.610, 95%CI 0.508-0.733, p < 0.001). Notably, nonlinear relationships through RCS (p 0.002). indicated particularly effective reducing among females, those education attainment, living partner. WQS identified saturated fatty acids as most significant factor contributing (weight 0.313). Additionally, BMI waist circumference (81.47 87.66%, respectively) partially mediated risk, suggesting operates, part, circumference. remained robust across multiple sensitivity analyses. Our findings indicate is linked lower providing crucial insights for strategies at mitigating epidemic simultaneously fostering environmental sustainability.
Language: Английский