Reply DOI Creative Commons
Vera Fortmeier, Mark Lachmann, Volker Rudolph

et al.

КАРДИОЛОГИЯ УЗБЕКИСТАНА, Journal Year: 2023, Volume and Issue: 16(12), P. 1550 - 1550

Published: June 1, 2023

Simplified Outcome Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention by Survival Tree-Based Modelling DOI Creative Commons
Vera Fortmeier, Mark Lachmann, Lukas Stolz

et al.

JACC Advances, Journal Year: 2025, Volume and Issue: 4(2), P. 101575 - 101575

Published: Jan. 22, 2025

Language: Английский

Citations

1

Applying the TRILUMINATE Eligibility Criteria to Real-World Patients Receiving Tricuspid Valve Transcatheter Edge-to-Edge Repair DOI Creative Commons
Lukas Stolz, Philipp M. Doldi, Karl‐Patrik Kresoja

et al.

КАРДИОЛОГИЯ УЗБЕКИСТАНА, Journal Year: 2023, Volume and Issue: 17(4), P. 535 - 548

Published: Nov. 20, 2023

Language: Английский

Citations

17

Inpatient Outcomes of Tricuspid Transcatheter Edge-to-Edge Repair in the United States Based on Sex DOI Creative Commons
Amanda Nguyen, Muhammad Zia Khan,

Waleed Alruwaili

et al.

Journal of the Society for Cardiovascular Angiography & Interventions, Journal Year: 2025, Volume and Issue: unknown, P. 102644 - 102644

Published: May 1, 2025

Language: Английский

Citations

0

The Appropriateness of Medical Devices Is Strongly Influenced by Sex and Gender DOI Creative Commons
Ilaria Campesi, Flavia Franconi, Pier Andrea Serra

et al.

Life, Journal Year: 2024, Volume and Issue: 14(2), P. 234 - 234

Published: Feb. 7, 2024

Until now, research has been performed mainly in men, with a low recruitment of women; consequentially, biological, physiological, and physio-pathological mechanisms are less understood women. Obviously, without data obtained on women, it is impossible to apply the results appropriately This issue also applies medical devices (MDs), numerous problems linked scarce pre-market clinical trials MDs were evidenced after their introduction market. Globally, some efficient women than men sometimes safe for although recently there small but significant decrease sex gender gap. As an example, cardiac resynchronization defibrillators seem produce more beneficial effects men. It important remember that can impact health healthcare providers this could occur sex- gender-dependent manner. Recently, MDs’ complexity rising, ensure appropriate use they must have sex–gender-sensitive approach. Unfortunately, majority physicians, providers, developers still believe human population only constituted by Therefore, overcome gap, real collaboration between inventors MDs, researchers, should be established test female male tissues, animals,

Language: Английский

Citations

3

Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry DOI Creative Commons
Karl‐Philipp Rommel, Guillaume Bonnet, Vera Fortmeier

et al.

European Journal of Heart Failure, Journal Year: 2024, Volume and Issue: 26(4), P. 1004 - 1014

Published: April 1, 2024

Abstract Aims While invasively determined congestion holds mechanistic and prognostic significance in acute heart failure (HF), its role patients with tricuspid regurgitation (TR)‐related right‐ (HF) undergoing transcatheter valve intervention (TTVI) is less well established. A comprehensive understanding of patterns might aid procedural planning, risk stratification, the identification who may benefit from adjunctive therapies before TTVI. The aim this study was to investigate severe TR implications for Methods results Within a multicentre, international TTVI registry, 813 underwent right catheterization (RHC) prior were followed up 24 months. median age 80 (interquartile range 76–83) years 54% women. Both mean atrial pressure (RAP) pulmonary capillary wedge (PCWP) associated 2‐year mortality on Cox regression analyses Youden index‐derived cut‐offs 17 mmHg 19 mmHg, respectively ( p < 0.01 all). However, RAP emerged as an independent predictor outcomes following multivariable adjustments. Pre‐interventionally, 42% classified euvolaemic (RAP <17 PCWP <19 mmHg), 23% having left‐sided ≥19 8% right‐sided ≥17 27% bilateral mmHg). Patients or had lowest success rates shortest survival times. Congestion allowed discerning specific patient's physiology specifying ventricular artery coupling surrogates. Conclusion In large cohort characterized TTVI, involving low higher after Whether pre‐interventional reduction can improve should be established dedicated studies.

Language: Английский

Citations

3

Efficacy and Safety of Cardioband in Patients with Tricuspid Regurgitation: Systematic Review and Meta-Analysis of Single-Arm Trials and Observational Studies DOI Open Access
Eugenia Piragine, Sara Veneziano, Sabrina Trippoli

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(21), P. 6393 - 6393

Published: Oct. 25, 2024

: The incidence and prevalence of tricuspid regurgitation (TR) are increasing worldwide. "Traditional" drug therapy with diuretics is often ineffective the identification new strategies, including non-pharmacological ones, an urgent need. aim this study was to summarize results on efficacy safety Cardioband, one few approved transcatheter valve repair systems, in patients TR.

Language: Английский

Citations

3

Artificial intelligence–enabled assessment of right ventricular to pulmonary artery coupling in patients undergoing transcatheter tricuspid valve intervention DOI
Vera Fortmeier, Mark Lachmann, Lukas Stolz

et al.

European Heart Journal - Cardiovascular Imaging, Journal Year: 2023, Volume and Issue: 25(4), P. 558 - 572

Published: Nov. 22, 2023

Right ventricular to pulmonary artery (RV-PA) coupling has been established as a prognostic marker in patients with severe tricuspid regurgitation (TR) undergoing transcatheter valve interventions (TTVI). RV-PA assesses right systolic function related pressure levels, which are ideally measured by heart catheterization. This study aimed improve the concept relating annular plane excursion (TAPSE) mean (mPAP) levels. Moreover, instead of catheterization, this sought employ an extreme gradient boosting (XGB) algorithm predict mPAP levels based on standard echocardiographic parameters. multicentre included 737 TTVI for TR; among them, 55 from one institution served external validation. Complete echocardiography and catheterization data were available all patients. The XGB trained 10 parameters could reliably evaluated validation (Pearson correlation coefficient R: 0.68; P value: 1.3 × 10-8). predicted (mPAPpredicted) superior (sPAPechocardiography) predicting 2-year mortality after [area under curve (AUC): 0.607 vs. 0.520; 1.9 10-6]. Furthermore, TAPSE/mPAPpredicted was TAPSE/sPAPechocardiography (AUC: 0.633 0.586; 0.008). Finally, preserved (defined > 0.617 mm/mmHg) showed significantly higher survival rates than reduced (81.5% 58.8%, < 0.001). independent association between confirmed multivariate regression analysis (P 6.3 10-4). Artificial intelligence-enabled assessment can refine risk stratification prior without necessitating invasive A comparison conservatively treated is mandatory quantify benefit accordance coupling.

Language: Английский

Citations

7

Sex-specific aspects of cardiovascular diseases DOI
Andrea Baessler, Pascal Bauer, Michael Becker

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 18(4), P. 293 - 321

Published: June 26, 2024

Kardiovaskuläre Erkrankungen sind weltweit sowohl bei Männern als auch Frauen die führende Todesursache. Durch fokussierte klinische und wissenschaftliche Untersuchungen hat sich das Verständnis für geschlechterspezifische Unterschiede in der Prävalenz, Pathophysiologie klinischen Präsentation von Herz-Kreislauf-Erkrankungen deutlich verbessert. Es ist mittlerweile unbestritten, dass kardiovaskuläre beiden Geschlechtern nicht immer identisch manifestieren, sondern Anatomie, Ätiologie, Pathophysiologie, Symptomatik sowie Verlauf, Therapieansprechen Prognose aufweisen können. Aktuelle Leitlinien Management kardiovaskulären berücksichtigen geschlechterspezifischen derzeit nur wenig, hauptsächlich da noch unzureichende Evidenz vorliegt, weil den Studien zu oft unterrepräsentiert sind. Das vorliegende Positionspapier DGK beleuchtet gezielt Aspekte relevanten Spezialisierungen Kardiologie. fasst bisher vorhandene zusammen gibt Empfehlungen, Symptomatik, Diagnose Therapie beachten Dadurch soll eine fundierte Grundlage personalisierte Behandlung Patienten geschaffen werden, geschlechterbezogene Berücksichtigung finden. unterstreicht Notwendigkeit weiterer Forschungsanstrengungen, ausreichende Anzahl weiblicher Probanden einschließen Maßnahmen zur Fort- Weiterbildung Ärzten medizinischem Fachpersonal umfassen. Eine konsequente geschlechterspezifischer kann Verbesserung Versorgungsqualität beitragen.

Citations

2

Outcomes and Complications of Mitral and Tricuspid Transcatheter Edge-to-edge Repair DOI Creative Commons
Jelena Arnautovic, Lina Ya’qoub, Zarghoona Wajid

et al.

Interventional Cardiology Reviews Research Resources, Journal Year: 2024, Volume and Issue: 19

Published: Oct. 28, 2024

In the realm of innovative medical procedures, TEER (transcatheter edge-to-edge repair) has emerged as a promising field, showcasing significant growth and advancements. Mitral been performed for last two decades; in contrast, tricuspid is newer, with long-term outcomes pending. This article aims to provide comprehensive review current literature, primary focus on potential complications associated both procedures. Both procedures carry low risk when done by experienced providers. A team approach involving specialists cardiology, cardiothoracic surgery, cardiac imaging heart failure ensures care. unified encompassing preprocedural workup, assessment, standardised care throughout procedure recovery contributes successful outcomes.

Language: Английский

Citations

1

Right Ventricular–Pulmonary Arterial Coupling DOI Creative Commons
Federico Fortuni, Giuseppe Ciliberti, Filippo Zilio

et al.

КАРДИОЛОГИЯ УЗБЕКИСТАНА, Journal Year: 2023, Volume and Issue: 16(12), P. 1549 - 1549

Published: June 1, 2023

Language: Английский

Citations

2