Key Imaging Factors for Transcatheter Management of Tricuspid Regurgitation: Device and Patient Selection DOI Open Access
F. Cannata, Kamil Stankowski, Michele Galasso

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(20), P. 6144 - 6144

Published: Oct. 15, 2024

The growing awareness of tricuspid regurgitation (TR) and the fast-expanding array devices aiming to percutaneously repair or replace valve have underscored central role multi-modality imaging in comprehensively assessing anatomical functional characteristics TR. Accurate phenotyping TR, right heart, pulmonary vasculature via echocardiography, computed tomography, and, occasionally, cardiovascular magnetic resonance heart catheterization is deemed crucial choosing most suitable treatment strategy for each patient achieving procedural success. In first part present review, key factors selection will be discussed. ensuing sections, an overview commonly used, commercially available systems transcatheter repair/replacement presented, along with their respective criteria information on intraprocedural guidance; these are edge-to-edge repair, orthotopic heterotopic replacement, valve-in-valve procedures.

Language: Английский

Transcatheter Valve Replacement in Severe Tricuspid Regurgitation DOI
Rebecca T. Hahn,

Raj Makkar,

Vinod H. Thourani

et al.

New England Journal of Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 30, 2024

BackgroundSevere tricuspid regurgitation is associated with disabling symptoms and an increased risk of death. Data regarding outcomes after percutaneous transcatheter tricuspid-valve replacement are needed.MethodsIn this international, multicenter trial, we randomly assigned 400 patients severe symptomatic in a 2:1 ratio to undergo either medical therapy (valve-replacement group) or alone (control group). The hierarchical composite primary outcome was death from any cause, implantation right ventricular assist device heart transplantation, postindex intervention, hospitalization for failure, improvement at least 10 points the score on Kansas City Cardiomyopathy Questionnaire overall summary (KCCQ-OS), one New York Heart Association (NYHA) functional class, 30 m 6-minute walk distance. A win calculated by comparing all possible patient pairs, starting first event hierarchy.ResultsA total 267 were valve-replacement group 133 control group. At 1 year, favoring valve 2.02 (95% confidence interval [CI], 1.56 2.62; P<0.001). In comparisons those had more wins than respect cause (14.8% vs. 12.5%), intervention (3.2% 0.6%), KCCQ-OS (23.1% 6.0%), NYHA class (10.2% 0.8%), distance (1.1% 0.9%). fewer annualized rate failure (9.7% 10.0%). Severe bleeding occurred 15.4% 5.3% (P=0.003); new permanent pacemakers implanted 17.4% 2.3%, respectively (P<0.001).ConclusionsFor regurgitation, superior outcome, driven primarily improvements quality life. (Funded Edwards Lifesciences; TRISCEND II ClinicalTrials.gov number, NCT04482062.)

Language: Английский

Citations

37
Benefit of isolated surgical valve repair or replacement for functional tricuspid regurgitation and long-term outcomes stratified by the TRI-SCORE DOI Creative Commons
Julien Dreyfus, Fernando M. Juarez-Casso, Alessandra Sala

et al.

European Heart Journal, Journal Year: 2024, Volume and Issue: 45(42), P. 4512 - 4522

Published: Aug. 30, 2024

Abstract Background and Aims Severe tricuspid regurgitation is associated with increased mortality rates, but benefit of its correction ideal timing are not clearly determined. This study aimed to identify patient subsets who might from the surgery. Methods In TRIGISTRY, an international cohort consecutive patients severe isolated functional (33 centres, 10 countries), survival rates up years were compared between underwent valve surgery (repair or replacement) those conservatively managed, overall according TRI-SCORE category (low: ≤3, intermediate: 4–5, high: ≥6). Results One thousand two hundred seventeen managed conservatively, 551 (200 repairs 351 replacements). distribution was 33% low, 32% intermediate, 35% high. At years, similar surgical conservative management [41% vs. 36%; hazard ratio (HR) .97; 95% confidence interval (CI) .88–1.08, P = .57]. Surgery improved in low (72% 44%; HR .27; CI .20–.37, &lt; .0001), intermediate (36% 37%; 1.17; 95%CI .98–1.40, .09) high categories (20% 24%; 1.06; .91–1.25, .45). Both repair replacement (84% 61% .11; .06–.19, .0001, .65; .47–.90, .009). Repair showed (59% .49; .35–.68, .0001) while possibly harmful (25% 1.43; 1.18–1.72, .0002). Conclusions Higher observed than intervention declined as no any type category. These results emphasize importance timely selection achieve best outcomes need for randomized controlled trials.

Language: Английский

Citations

9
TRIVALVE Score DOI
Giulio Russo,

Daniela Pedicino,

Denise Pires Marafon

et al.

КАРДИОЛОГИЯ УЗБЕКИСТАНА, Journal Year: 2024, Volume and Issue: 17(18), P. 2170 - 2179

Published: Sept. 1, 2024

Language: Английский

Citations

8
Refining the grading of tricuspid regurgitation: enhancing outcome prediction and patient management DOI
Julien Dreyfus, Patrizio Lancellotti, Ian G. Burwash

et al.

European Heart Journal - Cardiovascular Imaging, Journal Year: 2024, Volume and Issue: 25(8), P. 1085 - 1086

Published: May 27, 2024

Journal Article Accepted manuscript Refining the Grading of Tricuspid Regurgitation: Enhancing Outcome Prediction and Patient Management Get access Julien Dreyfus, MD, PhD, PhD Department Cardiology, Centre Cardiologique du Nord, Saint-Denis, France Address for correspondence: France. Tel: +33149334803, Fax: +33149334143, E-mail: [email protected] https://orcid.org/0000-0003-1338-3007 Search other works by this author on: Oxford Academic PubMed Google Scholar Patrizio Lancellotti, University Liège Hospital, GIGA Institute, CHU SartTilman, Liège, Belgium Ian G Burwash, MD Division Ottawa Heart Ottawa, Canada David Messika-Zeitoun, https://orcid.org/0000-0002-6278-5670 European - Cardiovascular Imaging, jeae141, https://doi.org/10.1093/ehjci/jeae141 Published: 28 May 2024 history Received: 16 Accepted: 18

Language: Английский

Citations

5
Transcatheter Tricuspid Valve Replacement DOI Creative Commons

Jörg Hausleiter,

Lukas Stolz, Philipp Lurz

et al.

Journal of the American College of Cardiology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

5
Atrial Functional Tricuspid Regurgitation (AFTR) Is Associated with Better Outcome After Tricuspid Transcatheter Edge-to-Edge Repair (T-TEER) Compared to Ventricular FTR (VFTR) DOI Open Access

Jinny Karin Scheffler,

Juliane Ott,

M. Jane Landes

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 794 - 794

Published: Jan. 25, 2025

Background: Transcatheter tricuspid edge-to-edge repair (T-TEER) is widely used to treat atrial (AFTR) and ventricular (VFTR) functional regurgitation (FTR). Methods: The outcome of 136 patients treated with T-TEER for severe AFTR or VFTR was analyzed using a composite endpoint all-cause death rehospitalization decompensated heart failure. defined as TR in the context left ejection fraction ≥50%, right fractional area change (RVFAC) ≥ 35% sPAP ≤ 50 mmHg. Results: Patients (N = 109) 27, 19.9%) were both elderly (82.0 {IQR: 74.5–84.5} vs. 82.0 75.0–84.0} years, p 0.98) had similar interventional risk according EuroScore II (6.1 {4.0–9.8} 4.7 {3.6–9.6} %, 0.3). Atrial fibrillation equally frequent groups (89.9 88.9%, 0.88). significantly more often female (56.0 77.8%, 0.04) lower NT-proBNP (3600.0 {1706.0–6302.0} 1988.0 {1034.8–3723.3} pg/mL, < 0.01). While RVFAC (29.5 ± 8.6 42.1 4.3%, 0.01) LVEF (48.5 12.3 58.6 8.0%, expectedly VFTR, dilation (RA volume: 126.7 56.5 127.6 74.2 mL, 0.99) similar. Successful reduction 2 degrees (96.3 92.6%, 0.34) observed groups, residual (94.5 96.3%, 1.0). incidence 1-year higher (34.3 12.0%) (log-rank 0.02). inversely associated (HR: 0.21, 95% CI: 0.06–0.7, multivariate Cox regression. Conclusions: Despite effective through T-TEER, better AFTR.

Language: Английский

Citations

0
Update zur echokardiografischen Beurteilung der Trikuspidalklappeninsuffizienz in der Praxis DOI
Maria Ivannikova,

Yasmine Echchihab,

Kai Friedrichs

et al.

Aktuelle Kardiologie, Journal Year: 2025, Volume and Issue: 14(01), P. 47 - 53

Published: Feb. 1, 2025

Zusammenfassung Die Trikuspidalklappeninsuffizienz (TI) ist eine häufige Herzklappenerkrankung mit erheblichen Auswirkungen auf die Patientenmorbidität und -letalität. In den letzten Jahren wurde Klassifikation der TI durch Einführung neuer Formen 5 Schweregrade verfeinert. Dabei spielt dreidimensionale Echokardiografie zunehmende Rolle in TI-Beurteilung -Graduierung sowie Bewertung rechtsventrikulären Funktion. Bei relevanter sollte Überweisung ein spezialisiertes Zentrum erfolgen.

Citations

0
One-Year Recurrent Tricuspid Regurgitation after Successful Transcatheter Edge to Edge Repair: the TRI-SPA Registry DOI
Julio Echarte‐Morales, Pedro Cepas‐Guillén, Dabit Arzamendi

et al.

The American Journal of Cardiology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Assessment of the GLIDE Score for Prediction of Mild Tricuspid Regurgitation following Tricuspid Transcatheter Edge-to-Edge Repair DOI Creative Commons
Felix Rudolph, Akhil Narang, Maria Isabel Körber

et al.

JACC Advances, Journal Year: 2025, Volume and Issue: 4(2), P. 101523 - 101523

Published: Feb. 1, 2025

The GLIDE Score is an anatomical scoring system designed to predict moderate residual tricuspid regurgitation (TR) immediately following transcatheter edge-to-edge repair (T-TEER). purpose of this study was evaluate the Score's predictive capability for achieving a postprocedural TR grade mild or better. This retrospective analysis included 336 patients from multicenter registry who underwent T-TEER between January 2017 and November 2022. Anatomical features were assessed using transesophageal echocardiography calculate Score, which ranges 0 5. primary endpoint better, via periprocedural imaging. Outcomes compared with Scores 1 those scores ≥2 logistic regression ROC curve analysis. Median age 81 years, no significant differences in BMI, EuroScore II, NYHA Class across cohorts. cohort had larger median RV basal diameter (48 mm vs 45 mm, P < 0.001) more torrential cases (35.9% 3.1%, 0.001). Postprocedural achieved 74.7% 1, versus 13.4% (P Ordinal found strong correlation severity (coefficient = 1.41, t 12.92), AUC 0.87 (95% CI: 0.83-0.90). valuable tool predicting patients, guiding patient selection refining treatment strategies.

Language: Английский

Citations

0
Right heart failure and mortality in patients undergoing transcatheter tricuspid valve interventions DOI
Edoardo Pancaldi, Marianna Adamo, Matteo Pagnesi

et al.

International Journal of Cardiology, Journal Year: 2025, Volume and Issue: unknown, P. 133137 - 133137

Published: March 1, 2025

Language: Английский

Citations

0