Nanomaterials-modulated Fenton reactions: Strategies, chemodynamic therapy and future trends

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 466, P. 142960 - 142960

Published: April 15, 2023

Language: Английский

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Multifaceted Carbonized Metal–Organic Frameworks Synergize with Immune Checkpoint Inhibitors for Precision and Augmented Cuproptosis Cancer Therapy

ACS Nano, Journal Year: 2024, Volume and Issue: 18(27), P. 17852 - 17868

Published: June 28, 2024

The discovery of cuproptosis, a copper-dependent mechanism programmed cell death, has provided way for cancer treatment. However, cuproptosis inherent limitations, including potential cellular harm, the lack targeting, and insufficient efficacy as standalone Therefore, exogenously controlled combination treatments have emerged key strategies cuproptosis-based oncotherapy. In this study, Cu2–xSe@cMOF nanoplatform was constructed combined sonodynamic/cuproptosis/gas therapy. This platform enabled precise cotreatment, with external control allowing selective induction in cells. approach effectively prevented metastasis recurrence. Furthermore, antiprogrammed death protein ligand-1 antibody (aPD-L1), maximized advantages immune checkpoint Additionally, under ultrasound irradiation, H2Se gas generated from induced cytotoxicity Further, it reactive oxygen species, which hindered survival proliferation. study reports an externally system that combines carbonized metal–organic framework aPD-L1 to enhance precision reinforced therapy could be valuable effective therapeutic agent reduce mortality morbidity future.

Language: Английский

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Immunoadjuvant-Functionalized Metal-Organic Frameworks：Synthesis and Applications in Tumor Immune Modulation

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

This review explores the synthesis, drug loading, and surface modifications of metal–organic frameworks (MOFs), highlighting their role in improving cancer immunotherapy paving way for safer more effective treatments.

Language: Английский

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Photogenerated carrier-accelerated 3D mesh-NH2 functionalized Zr-metal organic framework/MgAl-type hydrotalcite composites attacking diclofenac

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 354, P. 128839 - 128839

Published: July 16, 2024

Language: Английский

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Innovative MOF-5/V2CTx composite for high-performance, and ultra-fast supercapacitors and hydrogen evolution reaction

Electrochimica Acta, Journal Year: 2024, Volume and Issue: 489, P. 144277 - 144277

Published: April 16, 2024

Language: Английский

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Hierarchical CaZrO3@rGO nanostructure as an electrode material for high-performance supercapacitor devices

Diamond and Related Materials, Journal Year: 2024, Volume and Issue: 148, P. 111391 - 111391

Published: July 8, 2024

Language: Английский

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Developing TiCo2O4 spinel based on rGO nanosheet to enhance electrochemical performance of OER activity

Journal of Electroanalytical Chemistry, Journal Year: 2024, Volume and Issue: 963, P. 118299 - 118299

Published: April 26, 2024

Language: Английский

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Inorganic nanoparticle-based treatment approaches for colorectal cancer: recent advancements and challenges

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: July 19, 2024

Abstract Colorectal cancer, the third most prevalent cancer globally, contributes significantly to mortality rates, with over 1.9 million reported cases and nearly 935,000 fatalities annually. Surgical resection is a primary approach for localized colorectal tumors, adjunct therapies like chemotherapy, radiotherapy, targeted/immunotherapy considered depending on tumor stage. However, despite preferences targeted immunotherapy post-surgery, chemotherapy remains commonly chosen due its lower cost high cancer-killing efficiency. Yet, faces issues such as resistance severe side effects. Nanotechnology has emerged in therapy by alleviating drawbacks of current treatment approaches. In past few decades, inorganic nanoparticles have shown promise combating offering advantages conventional chemotherapy. Compared organic nanoparticles, exhibit properties photosensitivity, conductivity, magnetic allure, thermal proficiency, allowing them function both drug carriers therapeutic agents. Derived primarily from carbon, silica, metals, metal oxides, they offer superior drug-loading capacity, heightened quantum yield, participation advanced photothermal photodynamic therapies. This review provides brief overview pathophysiology pivotal role therapy, delivery. Additionally, it discusses numerous based recent literature. Graphical abstract

Language: Английский

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Construction of negative electrostatic sugared gourd pore within nickel-based metal-organic framework for one-step purification acetylene from ethylene and carbon dioxide mixture

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 154734 - 154734

Published: Aug. 17, 2024

Language: Английский

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Synthesis and application of novel sodium carboxy methyl cellulose-g-poly acrylic acid carbon dots hydrogel nanocomposite (NaCMC-g-PAAc/ CDs) for adsorptive removal of malachite green dye

Desalination and Water Treatment, Journal Year: 2024, Volume and Issue: unknown, P. 100822 - 100822

Published: Oct. 1, 2024

Language: Английский

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