Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(18), P. 11047 - 11136

Published: Sept. 7, 2023

Advances in nanotechnology and nanomaterials have attracted considerable interest play key roles scientific innovations diverse fields. In particular, increased attention has been focused on carbon-based exhibiting extended structures unique properties. Among these materials, zero-dimensional structures, including fullerenes, carbon nano-onions, nanodiamonds, dots, possess excellent bioaffinities superior fluorescence properties that make suitable for application to environmental biological sensing, imaging, therapeutics. This review provides a systematic overview of the classification structural properties, design principles preparation methods, optical sensing applications nanomaterials. Recent interesting breakthroughs sensitive selective imaging heavy metal pollutants, hazardous substances, bioactive molecules as well information encryption, super-resolution photoacoustic phototherapy nanomedicine delivery are main focus this review. Finally, future challenges prospects materials highlighted envisaged. presents comprehensive basis directions designing, developing, applying fascinating fluorescent sensors fabricated based specific requirements numerous research

Language: Английский

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Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

Advanced Drug Delivery Reviews, Journal Year: 2024, Volume and Issue: 207, P. 115239 - 115239

Published: March 3, 2024

Language: Английский

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Self‐Cascade Nanozyme Reactor as a Cuproptosis Inducer Synergistic Inhibition of Cellular Respiration Boosting Radioimmunotherapy

Small, Journal Year: 2024, Volume and Issue: 20(25)

Published: Jan. 14, 2024

Abstract Intrinsic or acquired radioresistance remained an important challenge in the successful management of cancer. Herein, a novel “smart” multifunctional copper‐based nanocomposite (RCL@Pd@CuZ) to improve radiotherapy (RT) sensitivity is designed and developed. In this nanoplatform, DSPE‐PEG‐RGD modified on liposome surface enhanced tumor targeting permeability; capsaicin inserted into phospholipid bilayer improved hypoxic conditions microenvironment (TME) by inhibiting mitochondrial respiration; Cu MOF porous cube encapsulated generated highly active hydroxyl radicals (OH · ), consumed GSH promoted cuproptosis releasing 2+ ; ultrasmall palladium (Pd) nanozyme within cubes exhibited peroxidase activity, catalyzing toxic OH generation oxygen from hydrogen peroxide; lastly, Pd, as element with relatively high atomic number (Z) photoelectric Compton effects X‐rays. Therefore, RCL@Pd@CuZ enhance RT ameliorating hypoxia, promoting cuproptosis, depleting GSH, amplifying oxidative stress, enhancing X‐ray absorption , consequently potently magnifying immunogenic cell death (ICD). mouse model combined yielded >90% inhibition compared that obtained alone addition greater quantity DC maturation CD8 + T infiltration. This nanoplatform offered promising remedial modality facilitate cuproptosis‐related cancer radioimmunotherapy.

Language: Английский

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Covalent Organic Framework/g-C₃N₄ van der Waals Heterojunction toward H₂ Production

Inorganic Chemistry, Journal Year: 2023, Volume and Issue: 62(7), P. 3271 - 3277

Published: Feb. 9, 2023

Photocatalytic water splitting into H2 is the most economic and environmentally friendly strategy for production, rationally constructing a heterojunction retains enormous influence on photocatalytic system. Herein, 2D/2D covalent organic framework/graphitic carbon nitride (COF/CN) van der Waals heterojunctions were readily prepared via an ultrasonic method high-efficiency visible-light production. The production performance of optimized COF/CN composites can reach up to 449.64 μmol·h-1, which approximately 5 times that pure CN (89.08 μmol·h-1). characterization experimental studies reveal synergistic effect between COF contributes promoting interfacial migration spatial separation photoinduced e--h+ pairs, further boosting hydrogen activity. This work may open new window design fabricate effective photocatalysts energy conversion.

Language: Английский

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Synergistic regulation of hydrophobicity and basicity for copper hydroxide‐derived copper to promote the CO ₂ electroreduction reaction

Carbon Energy, Journal Year: 2023, Volume and Issue: 5(6)

Published: Jan. 31, 2023

Abstract A simple method was proposed to activate alkaline Cu(OH) 2 with an acidic ionomer, Nafion, regulate its surface microenvironment, including hydrophobicity and local basicity. In particular, the direct complete neutralization reaction between Nafion in aqueous solution induces exposing of vast anions which can exclude in‐situ‐formed hydroxides raise Remarkably, optimal Nafion‐activated ‐derived Cu efficiently suppress hydrogen evolution (HER) improve selectivity for multi‐carbon products CO electroreduction (eCO RR). The H Faradaic efficiency (FE) decreased 11% at a current density 300 mA/cm (−0.76 V vs. RHE) flow cell, while bare one had FE 40%. total eCO RR reaches as high 83%, along evidently increased C 4 44% compared (24%), good stability (8000 s), surpassing that most reported Cu. experimental theoretical results both show strong basicity jointly boosted acquired by felicitously introducing ionomer on surface.

Language: Английский

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Facile Synthesis of Iron and Nitrogen Co-Doped Carbon Dot Nanozyme as Highly Efficient Peroxidase Mimics for Visualized Detection of Metabolites

Molecules, Journal Year: 2023, Volume and Issue: 28(16), P. 6064 - 6064

Published: Aug. 15, 2023

Visual detection based on nanozymes has great potential for the rapid of metabolites in clinical analysis or home-based health management. In this work, iron and nitrogen co-doped carbon dots (Fe,N-CDs) were conveniently synthesized as a nanozyme visual glucose (Glu) cholesterol (Chol). Using inexpensive readily available precursors, Fe,N-CDs with peroxidase-like activity prepared through simple hydrothermal method. Co-doping Fe N atoms enhanced catalytic nanozyme. The had low Michaelis constant (Km) 0.23 mM when hydrogen peroxide (H2O2) was used substrate. Free radical trapping experiments revealed that reactive oxygen species (ROS) generated nanozyme-catalyzed process superoxide anion radicals (•O2−), which can oxidize colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to generate blue oxidation product (ox-TMB) characteristics absorbance at 652 nm. Based mechanism, colorimetric sensor constructed detect H2O2 ranging from 0.1 μM 200 limit (DL) 75 nM. presence oxidase (Gox) Chol (Chox), Glu oxidized, respectively, H2O2. this, indirect realized linear ranges 5–160 2–200 DLs 2.8 0.8 μM, respectively. A paper-based platform fabricated using ink prepare testing paper by inkjet printing. smartphone record RGB values after reaction, be achieved (DL 3.3 μM) 1.0 μM),

Language: Английский

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Recent advances in carbon dots: synthesis and applications in bone tissue engineering

Nanoscale, Journal Year: 2023, Volume and Issue: 15(7), P. 3106 - 3119

Published: Jan. 1, 2023

The synthesis and applications of carbon dots in osteogenesis, fluorescence tracing, phototherapy antibacterial activity have been explored.

Language: Английский

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Synthetic Methods and Applications of Carbon Nanodots

Catalysts, Journal Year: 2023, Volume and Issue: 13(5), P. 858 - 858

Published: May 9, 2023

In the recent decade, carbon dots have drawn immense attention and prompted intense investigation. The latest form of nanocarbon, nanodot, is attracting intensive research efforts, similar to its earlier analogues, namely, fullerene, nanotube, graphene. One outstanding feature that distinguishes nanodots from other known forms materials water solubility owing extensive surface functionalization (the presence polar functional groups). These carbonaceous quantum dots, or nanodots, several advantages over traditional semiconductor-based dots. They possess photoluminescence, fluorescence, biocompatibility, biosensing bioimaging, photostability, feedstock sustainability, bio-conjugation, excellent colloidal stability, eco-friendly synthesis (from organic matter such as glucose, coffee, tea, grass biomass waste-derived sources), low toxicity, cost-effectiveness. Recent advances in characterization been received new insight provided. Presently applications fields drug delivery, sensing, diagnosis were highlighted future these astounding are speculated.

Language: Английский

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Recent research progress of fluorescence biosensors based on carbon dots in early diagnosis of diseases

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117962 - 117962

Published: Sept. 7, 2024

Language: Английский

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Quantum Yield Enhancement of Carbon Quantum Dots Using Chemical-Free Precursors for Sensing Cr (VI) Ions

Inorganics, Journal Year: 2024, Volume and Issue: 12(4), P. 96 - 96

Published: March 28, 2024

Quantum yield illustrates the efficiency that a fluorophore converts excitation light into fluorescence emission. The quantum of carbon dots (CQDs) can be altered via precursors, fabrication conditions, chemical doping, and surface modifications. In this study, CQDs were first fabricated from whole-meal bread using chemical-free hydrothermal route, low (0.81%) was obtained. combination bread, soybean flour, lemon juice generated with almost four folds enhancement in yield. Detailed characterization suggested these subjected to more complete reactions had zwitterionic surfaces. could selectively detect Cr (VI) ions limit detection (LOD) 8 ppm. This study shows does not need chemicals, it is achievable food precursors.

Language: Английский

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