Establishment of the Meyer-Overton correlation in an artificial membrane without protein DOI Creative Commons
Atsushi Matsumoto, Yukifumi Uesono

Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: unknown, P. 130717 - 130717

Published: Sept. 1, 2024

Language: Английский

Bottom-up development of lipid-based synthetic cells for practical applications DOI Creative Commons
Naresh Yandrapalli

Trends in biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Positioning Formation and Controllable Fabrication of Lipid Vesicles Using Patterned Substrates DOI Creative Commons
Hongmei Bi

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: May 15, 2025

Language: Английский

Citations

0
A study of Saponin-Encapsulated Ultrasound Microbubbles Rb3NPs@MBs for Atherosclerosis Targeted Treatment. DOI Creative Commons
Chunting Zhong,

Jianhua Bai,

Xiaoting Yang

et al.

Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Here we developed a new drug for treatment of atherosclerosis. It can clear 1/3 area the plaque targeting aortic arch within three weeks. brings hope rapid

Language: Английский

Citations

0
Ultrahigh yields of giant vesicles obtained through mesophase evolution and breakup DOI Open Access
Alexis Cooper, Anand Bala Subramaniam

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 4, 2024

Abstract Self-assembly odry amphiphilic lipid films on surfaces upon hydration is a crucial step in the formation of cell-like giant unilamellar vesicles (GUVs). GUVs are useful as model biophysical systems, chassis for synthetic biology, and biomedical applications. Here via combined quantitative measurements molar yield distributions sizes high-resolution imaging evolution surfaces, we report discovery previously unknown pathway assembly which can lead to ultrahigh yields > 50 %. This about 60 % higher than any GUV reported date. The “shear-induced fragmentation” occurs membranes containing 3 mol poly(ethylene glycol) modified PEG2000-DSPE (1,2-distearoyl- sn -glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]), when lipid-dense foam-like mesophase forms hydration. fragment close form application fluid shear. Experiments with varying lipids partial molecular similarity show that only achievable under conditions where forms. increased compared mixtures without was general other flat supporting such stainless steel sheets various mixtures. Since FDA-approved liposomal nanoparticle formulations use PEG2000-DSPE, these results provide route obtaining suitable

Language: Английский

Citations

1
Ultrahigh yields of giant vesicles obtained through mesophase evolution and breakup DOI Creative Commons
Alexis Cooper, Anand Bala Subramaniam

Soft Matter, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

We report the discovery of a novel mechanism for assembly giant unilamellar vesicles, where fluid shear-induced fragmentation foam-like lamellar lipid mesophase occurs in mixtures containing 3 mol% PEG2000-DSPE.

Language: Английский

Citations

1
Establishment of the Meyer-Overton correlation in an artificial membrane without protein DOI Creative Commons
Atsushi Matsumoto, Yukifumi Uesono

Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: unknown, P. 130717 - 130717

Published: Sept. 1, 2024

Language: Английский

Citations

0