
Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: unknown, P. 130717 - 130717
Published: Sept. 1, 2024
Language: Английский
Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: unknown, P. 130717 - 130717
Published: Sept. 1, 2024
Language: Английский
Trends in biotechnology, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0ACS Omega, Journal Year: 2025, Volume and Issue: unknown
Published: May 15, 2025
Language: Английский
Citations
0Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Here we developed a new drug for treatment of atherosclerosis. It can clear 1/3 area the plaque targeting aortic arch within three weeks. brings hope rapid
Language: Английский
Citations
0bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: June 4, 2024
Abstract Self-assembly odry amphiphilic lipid films on surfaces upon hydration is a crucial step in the formation of cell-like giant unilamellar vesicles (GUVs). GUVs are useful as model biophysical systems, chassis for synthetic biology, and biomedical applications. Here via combined quantitative measurements molar yield distributions sizes high-resolution imaging evolution surfaces, we report discovery previously unknown pathway assembly which can lead to ultrahigh yields > 50 %. This about 60 % higher than any GUV reported date. The “shear-induced fragmentation” occurs membranes containing 3 mol poly(ethylene glycol) modified PEG2000-DSPE (1,2-distearoyl- sn -glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]), when lipid-dense foam-like mesophase forms hydration. fragment close form application fluid shear. Experiments with varying lipids partial molecular similarity show that only achievable under conditions where forms. increased compared mixtures without was general other flat supporting such stainless steel sheets various mixtures. Since FDA-approved liposomal nanoparticle formulations use PEG2000-DSPE, these results provide route obtaining suitable
Language: Английский
Citations
1Soft Matter, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
We report the discovery of a novel mechanism for assembly giant unilamellar vesicles, where fluid shear-induced fragmentation foam-like lamellar lipid mesophase occurs in mixtures containing 3 mol% PEG2000-DSPE.
Language: Английский
Citations
1Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2024, Volume and Issue: unknown, P. 130717 - 130717
Published: Sept. 1, 2024
Language: Английский
Citations
0