Hydrogel Applications in the Diagnosis and Treatment of Glioblastoma DOI
S.H. Zhang, Renming Zhong, Muhammad Rizwan Younis

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Glioblastoma multiforme (GBM), a common malignant neurological tumor, has boundaries indistinguishable from those of normal tissue, making complete surgical removal ineffective. The blood-brain barrier (BBB) further impedes the efficacy radiotherapy and chemotherapy, leading to suboptimal treatment outcomes heightened probability recurrence. Hydrogels offer multiple advantages for GBM diagnosis treatment, including overcoming BBB improved drug delivery, controlled release long-term efficacy, enhanced relaxation properties magnetic resonance imaging (MRI) contrast agents. Hydrogels, with their excellent biocompatibility customizability, can mimic

Language: Английский

Valorization of sewage sludge organic matter for polyacrylamide-based greener hydrogel production with good salt resistance and high permeability DOI
Fan Gao, Lijian Leng, Huan Yang

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136418 - 136418

Published: Feb. 1, 2025

Language: Английский

Citations

0

Green synthesized silver nanoparticles based on N-3-(dimethylamino)propyl methacrylamide/2-hydroxyethyl methacrylate hydrogels for antibacterial wound dressing material DOI
Elif Şeref, Özgür Özay

Journal of Macromolecular Science Part A, Journal Year: 2024, Volume and Issue: 61(9), P. 675 - 690

Published: Aug. 24, 2024

In this study, hydrogels were synthesized using Prunus persica ev. Bayramiç Beyazı extract as a crosslinker. N-3-(Dimethylamino)propyl methacrylamide (DMAPMA) and 2-Hydroxyethyl methacrylate (HEMA) monomers used in by redox polymerization. Hydrogel@Ag composites created synthesizing Ag0 nanoparticles within hydrogel network structures cross-linked with plant an in-situ green synthesis method. These characterized swelling, FTIR, TEM, XRD, TGA methods. The hydrogel@Ag loaded Naproxen Cefazolin drugs. in-vitro drug release profiles of the examined pH = 5.5 PBS environment, it was determined that approximately 75% drugs released 5 h. kinetics model for Higuchi model, followed Korsmeyer-Peppas model. nanoparticle encapsulation significantly affected degree swelling. MBA showed swelling capacity 370.16% mass, while fruit exhibited 1000.78% mass. silver-encapsulated demonstrated even higher 2313% Additionally, antibacterial tests against Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis microorganisms, Ag-free did not exhibit activity.

Language: Английский

Citations

1

Hydrogel Applications in the Diagnosis and Treatment of Glioblastoma DOI
S.H. Zhang, Renming Zhong, Muhammad Rizwan Younis

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Glioblastoma multiforme (GBM), a common malignant neurological tumor, has boundaries indistinguishable from those of normal tissue, making complete surgical removal ineffective. The blood-brain barrier (BBB) further impedes the efficacy radiotherapy and chemotherapy, leading to suboptimal treatment outcomes heightened probability recurrence. Hydrogels offer multiple advantages for GBM diagnosis treatment, including overcoming BBB improved drug delivery, controlled release long-term efficacy, enhanced relaxation properties magnetic resonance imaging (MRI) contrast agents. Hydrogels, with their excellent biocompatibility customizability, can mimic

Language: Английский

Citations

1