Stomatitis Healing via Hydrogels Comprising Proline, Carboxyvinyl Polymer, and Water

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 108 - 108

Published: Feb. 3, 2025

Chemotherapy using anticancer agents and radiotherapy of cancers frequently induce the development stomatitis as a side effect. In present study, hydrogels for effective healing under drug administration were developed three components, namely proline, carboxyvinyl polymer, water (denoted proline gels). Characterization including tilting, Fourier transform infrared spectra, viscoelasticity measurements indicated that gels with concentrations over 300 μmol/g could retain on tongue mice. The degradation release behavior in serological environments evaluated, revealing degraded by salt concentrations, cumulative amount released from depended concentration gel. Proline applied to area mice administration, subsequent reduction regeneration mucosal epithelium layer, demonstrating 500 μmol/g. Other control samples polymer or alone did not reduce model These results suggested gel is promising mucosa drug-induced stomatitis.

Language: Английский

Wearable artificial kidney technology for toxin removal: The need, opportunities, and challenges in incorporating advanced materials

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161659 - 161659

Published: March 1, 2025

Language: Английский

Antibacterial antioxidant polyurethane/curcumin patch with anti-swelling ability for tissue adhesion and treatment of oral ulcers

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162131 - 162131

Published: March 1, 2025

Language: Английский