An injectable, self-healing, anti-infective, and anti-inflammatory novel glycyrrhizic acid hydrogel for promoting acute wound healing and regeneration
Q. J. Guo,
No information about this author
Ruojing Li,
No information about this author
Yeying Zhao
No information about this author
et al.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
12
Published: Jan. 10, 2025
Bacterial
infection,
a
complex
wound
microenvironment,
and
persistent
inflammatory
response
in
acute
wounds
can
result
delayed
healing
abnormal
scar
formation,
thereby
compromising
the
normal
function
aesthetic
appearance
of
skin
tissue.
This
issue
represents
one
most
challenging
problems
clinical
practice.
study
aims
to
develop
hydrogel
dressing
specifically
designed
for
treatment
wounds,
providing
immediate
effective
protection
affected
areas.
innovation
seeks
offer
novel
advanced
solution
management
wounds.
In
this
study,
composite
scaffold
was
synthesized
through
reaction
between
oxidized
glycyrrhizic
acid
carboxymethyl
chitosan
Schiff
base.
The
material
properties
were
systematically
characterized,
its
biocompatibility
antibacterial
efficacy
rigorously
evaluated.
A
rat
model
established
compare
multiple
groups,
assessing
impact
on
microenvironment
repair.
results
demonstrated
that
OGA-CMCS
exhibited
excellent
injectability,
biocompatibility,
properties.
It
capable
enhancing
which
turn
influenced
polarization
macrophages
from
M1
M2
phenotype,
mitigating
response,
promoting
angiogenesis
granulation
tissue
regeneration,
accelerating
healing.
successfully
developed
glycyrrhizin-based
dressing,
not
only
introduces
innovative
approaches
emergency
surface
defects
but
also
provides
an
experimental
foundation.
is
anticipated
contribute
significantly
addressing
relevant
challenges.
Language: Английский
Highly hydrophobic MXene/PS@polypropylene fabric for human posture recognition assisted by machine learning
Daihui Zhang,
No information about this author
Chunqing Yang,
No information about this author
Jun Wang
No information about this author
et al.
Journal of Materials Chemistry C,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
MXene/PS@polypropylene
fabric
pressure
sensors
can
detect
yoga
movements,
and
combined
with
deep
belief
networks,
the
accuracy
of
recognizing
different
movements
exceeds
91%.
Language: Английский
Hydrogel contact lenses modified by quaternary chitosan and epigallocatechin gallate with enhancement of antimicrobial for bacterial keratitis
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
306, P. 141787 - 141787
Published: March 6, 2025
Language: Английский
Modified multilayered porous titanium scaffolds with silicon-doped coating surface-loaded BMP-2 prepared by microarc oxidation for bone defect repair
X. L. Zhang,
No information about this author
Xu Zhang,
No information about this author
Wuchao Zhou
No information about this author
et al.
Surface and Coatings Technology,
Journal Year:
2024,
Volume and Issue:
495, P. 131570 - 131570
Published: Nov. 16, 2024
Language: Английский