Making the Complicated Simple: A Minimizing Carrier Strategy on Innovative Nanopesticides DOI Creative Commons
Wenjie Shangguan, Qiliang Huang, Huiping Chen

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: May 14, 2024

The flourishing progress in nanotechnology offers boundless opportunities for agriculture, particularly the realm of nanopesticides research and development. However, concerns have been raised regarding human environmental safety issues stemming from unrestrained use non-therapeutic nanomaterials nanopesticides. It is also important to consider whether current development strategy based on nanocarriers can strike a balance between investment return, if complex material composition genuinely improves efficiency, safety, circularity Herein, we introduced concept with minimizing carriers (NMC) prepared through prodrug design molecular self-assembly emerging as practical tools address limitations, compared it employing (NNC). We further summarized NMC examined potential challenges its preparation, performance, production. Overall, asserted that systems serve innovative driving force catalyzing green efficient revolution nanopesticides, offering way out predicament.

Language: Английский

Doxorubicin covalently conjugated heparin displays anti-cancer activity as a self-assembled nanoparticle with a low-anticoagulant effect DOI

Jae-Hyeon Lee,

Seong-Bin Yang,

Jun Hyuck Lee

et al.

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 314, P. 120930 - 120930

Published: April 18, 2023

Language: Английский

Citations

23

Bilirubin/morin self-assembled nanoparticle-engulfed collagen/polyvinyl alcohol hydrogel accelerates chronic diabetic wound healing by modulating inflammation and ameliorating oxidative stress DOI
Ying‐Zheng Zhao,

Chu-Chu Du,

Yunxia Xuan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129704 - 129704

Published: Jan. 23, 2024

Language: Английский

Citations

15

Self-assembled nanodrug delivery systems for anti-cancer drugs from traditional Chinese medicine DOI
Li Qiao,

Yuan Lianghao,

Gao Shijie

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(7), P. 1662 - 1692

Published: Jan. 1, 2024

In this review, we have summarized the common self-assembled mechanism of NSMs-based SANDDSs. Meanwhile, potential applications for cancer treatment and future development prospects are also prospected.

Language: Английский

Citations

15

Natural-product-based, carrier-free, noncovalent nanoparticles for tumor chemo-photodynamic combination therapy DOI Creative Commons
Zhonglei Wang, Liyan Yang

Pharmacological Research, Journal Year: 2024, Volume and Issue: 203, P. 107150 - 107150

Published: March 21, 2024

Cancer, with its diversity, heterogeneity, and complexity, is a significant contributor to global morbidity, disability, mortality, highlighting the necessity for transformative treatment approaches. Photodynamic therapy (PDT) has aroused continuous interest as viable alternative conventional cancer treatments that encounter drug resistance. Nanotechnology brought new advances in medicine shown great potential delivery treatment. For precise efficient therapeutic utilization of such tumor approach high spatiotemporal selectivity minimal invasiveness, carrier-free noncovalent nanoparticles (NPs) based on chemo-photodynamic combination essential. Utilizing natural products foundation nanodrug development offers unparalleled advantages, including exceptional pharmacological activity, easy functionalization/modification, well biocompatibility. The natural-product-based, carrier-free, NPs revealed excellent synergistic anticancer activity comparison free photosensitizers bioactive products, representing an favorable avenue improve efficacy. Herein, comprehensive summary current strategies representative application examples past decade (such paclitaxel, 10-hydroxycamptothecin, doxorubicin, etoposide, combretastatin A4, epigallocatechin gallate, curcumin) therapy. We highlight insightful design synthesis smart aim enhance PDT Meanwhile, we discuss future challenges opportunities associated these provide enlightenment, spur innovative ideas, facilitate PDT-mediated clinical transformation.

Language: Английский

Citations

15

Making the Complicated Simple: A Minimizing Carrier Strategy on Innovative Nanopesticides DOI Creative Commons
Wenjie Shangguan, Qiliang Huang, Huiping Chen

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 16(1)

Published: May 14, 2024

The flourishing progress in nanotechnology offers boundless opportunities for agriculture, particularly the realm of nanopesticides research and development. However, concerns have been raised regarding human environmental safety issues stemming from unrestrained use non-therapeutic nanomaterials nanopesticides. It is also important to consider whether current development strategy based on nanocarriers can strike a balance between investment return, if complex material composition genuinely improves efficiency, safety, circularity Herein, we introduced concept with minimizing carriers (NMC) prepared through prodrug design molecular self-assembly emerging as practical tools address limitations, compared it employing (NNC). We further summarized NMC examined potential challenges its preparation, performance, production. Overall, asserted that systems serve innovative driving force catalyzing green efficient revolution nanopesticides, offering way out predicament.

Language: Английский

Citations

15