T Cell and Natural Killer Cell Membrane-Camouflaged Nanoparticles for Cancer and Viral Therapies DOI Creative Commons

Fatma Ozsoy,

Mahir M. Sharif, Nasrullah Jan

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(5), P. 2637 - 2659

Published: April 30, 2024

Extensive research has been conducted on the application of nanoparticles in treatment cancer and infectious diseases. Due to their exceptional characteristics flexible structure, they are classified as highly efficient drug delivery systems, ensuring both safety targeted delivery. Nevertheless, still encounter obstacles, such biological instability, absence selectivity, recognition unfamiliar elements, quick elimination, which restrict remedial capacity. To surmount these drawbacks, biomimetic nanotechnology developed that utilizes T cell natural killer (NK) membrane-encased sophisticated methods administering drugs. These can extend duration circulation avoid immune system clearance. During membrane extraction coating procedure, surface proteins immunological cells transferred nanoparticles. Such present confer several benefits nanoparticles, including prolonged circulation, enhanced targeting, controlled release, specific cellular contact, reduced vivo toxicity. This review focuses nanosystems derived from membranes NK comprehensive manufacture, applications viral infections. Furthermore, potential applications, prospects, existing challenges medical implementation highlighted.

Language: Английский

Targeted delivery of nano-radiosensitizers for tumor radiotherapy DOI

Shuzhi Shi,

Haibo Zhong,

Yong Zhang

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 518, P. 216101 - 216101

Published: July 27, 2024

Language: Английский

Citations

8

Design, Synthesis, and Diverse Applications of Cu-Based Photocatalysts: A Review DOI

Ying Du,

Yanting Tang, Xinqi Ma

et al.

Crystal Growth & Design, Journal Year: 2024, Volume and Issue: 24(6), P. 2592 - 2618

Published: March 4, 2024

With the increasing variety of Cu-based semiconductor nanomaterials and development synthesis technology, crystal shape morphology materials have become controllable factors. Due to their low price, abundant reserves, suitable band gap, bright application prospects for treatment photocatalytic environments. A comprehensive summary basic theory research progress nanomaterials, such as design, control, modification strategies mechanisms, is indispensable. However, a review this aspect has not been reported recently. This summarizes synthetic methods copper oxides (CuO, Cu2O), sulfides (CuS, CuxS, Cu2S), selenides (CuSe, Cu2–xSe, Cu2Se), well other novel CuFe2O4, Cu3N, Cu5V2O10, CuCo2O4, CuWO4, Cu3P, mechanisms in removal pollutants, hydrogen evolution, reduction CO2. The surface control beneficial preparation better catalysts. We firmly believe that can provide valuable information further nanomaterials.

Language: Английский

Citations

7

Curcumin-loaded mesoporous polydopamine nanoparticles modified by quaternized chitosan against bacterial infection through synergistic effect DOI
Xiao Han, Weijia Gao, Zhe Zhou

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 267, P. 131372 - 131372

Published: April 3, 2024

Language: Английский

Citations

7

Enhancing X‐Ray Sensitization with Multifunctional Nanoparticles DOI Creative Commons
Jiayi Liu, Junyong Wu, Taili Chen

et al.

Small, Journal Year: 2024, Volume and Issue: 20(35)

Published: April 26, 2024

Abstract In the progression of X‐ray‐based radiotherapy for treatment cancer, incorporation nanoparticles (NPs) has a transformative impact. This study investigates potential NPs, particularly those comprised high atomic number elements, as radiosensitizers. aims to optimize localized radiation doses within tumors, thereby maximizing therapeutic efficacy while preserving surrounding tissues. The multifaceted applications NPs in encompass collaborative interactions with chemotherapeutic, immunotherapeutic, and targeted pharmaceuticals, along contributions photodynamic/photothermal therapy, imaging enhancement, integration artificial intelligence technology. Despite promising preclinical outcomes, paper acknowledges challenges clinical translation these findings. conclusion maintains an optimistic stance, emphasizing ongoing trials technological advancements that bolster personalized approaches. advocates continuous research validation, envisioning revolutionary paradigm cancer ultimately enhancing patient outcomes.

Language: Английский

Citations

7

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation DOI
Mehrdad Hashemi, Fatemeh Ghadyani, Sahar Hasani

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 80, P. 104112 - 104112

Published: Dec. 26, 2022

Language: Английский

Citations

28

Chemoradiation therapy of 4T1 cancer cells with methotrexate conjugated platinum nanoparticles under X-Ray irradiation DOI

Kadir Yaray,

Abdolvahed Norbakhsh,

Hamid Rashidzadeh

et al.

Inorganic Chemistry Communications, Journal Year: 2023, Volume and Issue: 150, P. 110457 - 110457

Published: Feb. 1, 2023

Language: Английский

Citations

14

Electrospun Cu–Co ferrite nanofibers: synthesis, structure, optical and magnetic properties, and anti-cancer activity DOI Creative Commons
Fatimah Alahmari, Firdos Alam Khan,

H. Sözeri

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(11), P. 7540 - 7550

Published: Jan. 1, 2024

In this study, we investigated Cu-Co ferrite nanofibers (NFs) that were synthesized for the first time employing electrospinning technique. The structure, phase purity and crystallite size of all prepared NFs revealed by powder X-ray diffraction (PXRD) analysis. crystallized in Fd3̄m (no. 227) space group cation distribution arrangement over distinct sites their structure was analyzed. Scanning electron microscopy (SEM) together with energy-dispersive (EDX) spectroscopy analysis showed microstructure verified expected chemical compositions. High-resolution transmission (TEM) images confirmed fibrous nature construction NFs. band gap energies derived from UV-vis reflectance spectra a blue shift an increase amount Cu sample 1.42 eV to 1.86 eV. Magnetization (M) as function magnetic field (H) measurements performed at ambient low temperatures ferrimagnetic behavior parameters including coercivity (Hc), saturation magnetization (Ms), remanent (Mr), squareness ratio determined recorded curves. At 300 K, Ms reduced 78.8 42.4 emu g-1, Mr 22.8 7.6 g-1 Bohr magneton 3.3 1.8μB content samples. same trend observed 10 where 93.7 50.9 60.9 35.9 3.94 2.16μB. Alternatively, Hc has highest values x = 0 (850 Oe K 5220 K) 0.6 (800 5400 K). anti-cancer activity evaluated using MTT cell viability assay, showing reduction both HCT-116 HeLa cancer cells compared non-cancerous HEK-293 after treatment Apoptotic examined DAPI staining, induced chromatin condensation nuclear disintegration cells.

Language: Английский

Citations

5

Autophagy flux in bladder cancer: Cell death crosstalk, drug and nanotherapeutics DOI
Kuan Liu, Huijing Chen, Yanhong Li

et al.

Cancer Letters, Journal Year: 2024, Volume and Issue: 591, P. 216867 - 216867

Published: April 7, 2024

Language: Английский

Citations

5

Chitosan-based nanoscale delivery systems in hepatocellular carcinoma: Versatile bio-platform with theranostic application DOI
Kimia Karimi,

Sarah Mojtabavi,

Pooya M. Tehrany

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 242, P. 124935 - 124935

Published: May 23, 2023

Language: Английский

Citations

11

Nanoliposomes as nonviral vectors in cancer gene therapy DOI Creative Commons
Ş. Yildiz,

Maliheh Entezari,

Mahshid Deldar Abad Paskeh

et al.

MedComm, Journal Year: 2024, Volume and Issue: 5(7)

Published: June 25, 2024

Abstract Nonviral vectors, such as liposomes, offer potential for targeted gene delivery in cancer therapy. Liposomes, composed of phospholipid vesicles, have demonstrated efficacy nanocarriers genetic tools, addressing the limitations off‐targeting and degradation commonly associated with traditional therapy approaches. Due to their biocompatibility, stability, tunable physicochemical properties, they overcoming challenges therapy, low transfection efficiency poor stability biological fluids. Despite these advancements, there remains a gap understanding optimal utilization nanoliposomes enhanced treatment. This review delves into present state carriers tools sheds light on safeguard payloads facilitate cell internalization alongside evolution smart delivery. The linked biocompatibility factors that restrict effectiveness are also discussed along exploring strategies by analyzing recent advancements offering future directions.

Language: Английский

Citations

4