Biocompatible microneedles with engineered indentation design fabricated via vat photopolymerization for enhanced transdermal drug delivery
Aqila Che Ab Rahman,
No information about this author
Siyoung Yang,
No information about this author
Sooman Lim
No information about this author
et al.
European Polymer Journal,
Journal Year:
2025,
Volume and Issue:
unknown, P. 113818 - 113818
Published: Feb. 1, 2025
Language: Английский
Bidirectional Object Transport on Biomimetic Setal Array with Friction Anisotropy
Zongke Zhou,
No information about this author
Tianyuan Liu,
No information about this author
Xuejiang Gu
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et al.
Tribology Letters,
Journal Year:
2025,
Volume and Issue:
73(2)
Published: April 10, 2025
Language: Английский
White Roman Goose Feather-Inspired Unidirectionally Inclined Conical Structure Arrays for Switchable Anisotropic Self-Cleaning
You-Jie Chen,
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Cai-Yin Fang,
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Yun‐Wen Huang
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et al.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(28), P. 36840 - 36850
Published: July 2, 2024
White
Roman
goose
(Anser
anser
domesticus)
feathers,
comprised
of
oriented
conical
barbules,
are
coated
with
gland-secreted
preening
oils
to
maintain
a
long-term
nonwetting
performance
for
surface
swimming.
The
geese
accustomed
combing
their
plumages
flat
bills
in
case
they
contaminated
oleophilic
substances,
during
which
the
amphiphilic
saliva
spread
over
barbules
greatly
impairs
hydrophobicities
and
allows
trapped
contaminants
be
anisotropically
self-cleaned
by
water
flows.
Particularly,
superhydrophobic
behaviors
feathers
recovered
as
well.
Bioinspired
switchable
anisotropic
self-cleaning
functionality
white
geese,
unidirectionally
inclined
structures
engineered
through
integration
scalable
colloidal
self-assembly
technology
lithographic
approach.
dependence
directional
sliding
properties
on
shape,
inclination
angle,
size
is
systematically
investigated
this
research.
Moreover,
functionalities
demonstrated
Sudan
blue
II/water
(0.01%)
separation
performances.
feather-inspired
coatings
undoubtedly
offer
new
concept
developing
innovative
applications
that
require
transportation
collection
liquids.
Language: Английский
Bioinspired 3D‐Printed NIR‐Responsive MXene‐Based Multifunctional Eutectogel Microneedles for Personalized Infected Wound Healing
Huan Liu,
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Aminov Nail,
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Decheng Meng
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et al.
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 6, 2025
Abstract
Infected
wound
healing
remains
a
significant
clinical
challenge,
demanding
innovative
therapeutic
strategies
to
simultaneously
address
bacterial
elimination,
tissue
regeneration,
and
controlled
drug
delivery.
Inspired
by
the
hierarchical
structure
of
crocodile
teeth,
bioinspired,
3D‐printed
microneedle
patch
integrating
Mxene
nanosheets
polymerizable
deep
eutectic
solvent
(PDES)
composed
vinyl
pyrrolidone
(VP),
itaconic
acid
(IA),
N‐isopropyl
acrylamide
(NIPAM)
is
developed.
The
resulting
MXene‐based
eutectogel
(MF‐MXene@MN)
combines
photothermal
responsiveness,
antioxidant
activity,
temperature‐triggered
release
for
conversion
reactive
oxygen
species
(ROS)
scavenging.
gradient‐height
design
inspired
teeth
enhances
adhesion,
while
DLP
3D
printing
enables
personalized
dressing
geometries
with
<50
µm
resolution.
In
vitro
in
vivo
studies
demonstrated
94.88%
closure
rate
within
10
days,
3.2‐fold
increased
angiogenesis,
68%
reduced
viability
(
S.
aureus
:
32.59%;
E.
coli
48.17%
under
NIR),
pH‐/temperature‐responsive
mangiferin
(88.3%
cumulative
via
5
NIR
cycles).
These
synergistic
functions
promote
healing,
offering
superior
antibacterial
ability,
regeneration
promotion,
control
compared
traditional
dressings
systems.
This
multifunctional
platform
integrates
bioinspired
design,
stimuli‐responsive
materials,
additive
manufacturing,
providing
transformative
solution
precision
management.
Language: Английский
Laser Direct Writing of Setaria Virids-Inspired Hierarchical Surface with TiO2 Coating for Anti-Sticking of Soft Tissue
Qingxu Zhang,
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Yanyan Yang,
No information about this author
Shijie Huo
No information about this author
et al.
Micromachines,
Journal Year:
2024,
Volume and Issue:
15(9), P. 1155 - 1155
Published: Sept. 15, 2024
In
minimally
invasive
surgery,
the
tendency
for
human
tissue
to
adhere
electrosurgical
scalpel
can
complicate
procedures
and
elevate
risk
of
medical
accidents.
Consequently,
development
an
with
anti-sticking
coating
is
critically
important.
Drawing
inspiration
from
nature,
we
identified
that
leaves
Setaria
Virids
exhibit
exceptional
non-stick
properties.
Utilizing
this
natural
surface
texture
as
a
model,
designed
fabricated
specialized
scalpels.
Employing
nanosecond
laser
direct
writing
ablation
technology,
created
micro-nano
textured
on
high-frequency
mimics
structure
found
leaves.
Subsequently,
TiO2
was
deposited
onto
ablated
via
magnetron
sputtering,
followed
by
plasma-induced
hydrophobic
modification
treatment
octadecyltrichlorosilane
(OTS)
enhance
surface’s
affinity
silicone
oil,
thereby
constructing
self-lubricating
surface.
The
spreading
behavior
deionized
water,
absolute
ethanol,
dimethyl
oil
investigated
confirm
effectiveness
self-lubrication
mechanism.
Furthermore,
sticking
force
quality
are
compared
between
standard
demonstrate
efficacy
laser-ablated
in
preventing
sticking.
findings
indicate
using
exhibits
superior
Language: Английский