Microneedle-Based Approaches for Skin Disease Treatment DOI Creative Commons

Yanhua Han,

Xiaoyu Qin, Weisen Lin

et al.

Nano-Micro Letters, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 6, 2025

Abstract The use of microneedles (MNs) has been established as an effective transdermal drug delivery strategy that extensively deployed for treating various diseases, including skin diseases. MNs can surpass the constraints conventional methods by their superior safety and efficacy through precise targeting, while simultaneously enabling painless delivery. Currently, are increasingly used carriers delivery, with loading insoluble drugs to improve treatment efficiency or combining bioactive substances construction efficient system maximize effects substances. preparation diverse, them meet requirements most applications. emergence addressed shortcomings associated drugs, expanded applications substances, improved in clinical practice. This review summarizes current information on application a variety such psoriasis, vitiligo, alopecia, hypertrophic scarring, atopic dermatitis, melanoma, acne, infections. future opportunities diseases also discussed. Despite substantial progress vectors, issues low poor mechanical strength during remain main challenges. Therefore, implementation MNs-based therapies remains limited, highlighting key research.

Language: Английский

Microneedle-Based Approaches for Skin Disease Treatment DOI Creative Commons

Yanhua Han,

Xiaoyu Qin, Weisen Lin

et al.

Nano-Micro Letters, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 6, 2025

Abstract The use of microneedles (MNs) has been established as an effective transdermal drug delivery strategy that extensively deployed for treating various diseases, including skin diseases. MNs can surpass the constraints conventional methods by their superior safety and efficacy through precise targeting, while simultaneously enabling painless delivery. Currently, are increasingly used carriers delivery, with loading insoluble drugs to improve treatment efficiency or combining bioactive substances construction efficient system maximize effects substances. preparation diverse, them meet requirements most applications. emergence addressed shortcomings associated drugs, expanded applications substances, improved in clinical practice. This review summarizes current information on application a variety such psoriasis, vitiligo, alopecia, hypertrophic scarring, atopic dermatitis, melanoma, acne, infections. future opportunities diseases also discussed. Despite substantial progress vectors, issues low poor mechanical strength during remain main challenges. Therefore, implementation MNs-based therapies remains limited, highlighting key research.

Language: Английский

Citations

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