
Multidisciplinary Respiratory Medicine, Journal Year: 2025, Volume and Issue: 20(Vol. 20 (2025))
Published: Feb. 28, 2025
Background: Tuberculosis (TB) treatment non-compliance remains a significant global public health issue, undermining disease control efforts and leading to adverse clinical epidemiological outcomes. While considerable research has explored this gaps remain in understanding the multifactorial influences on non-compliance, particularly its key factors impacts, as well interconnections that exacerbate these challenges. This study integrates narrative bibliometric approaches critically synthesize visualize contributing TB impacts. By addressing gaps, aims provide comprehensive framework for challenges proposing evidence-informed strategies address issues. Methods: A systematic search of Scopus, EBSCO (Medline), ScienceDirect, PubMed databases identified empirical studies published up December 2024. Thematic synthesis categorized into overarching themes, while analysis using VOSviewer software visualized their interconnections. Results: The review such poor tuberculosis knowledge, stigma, side effects, economic constraints, interacting with demographic, psychological, systemic barriers. Network visualization highlighted among factors, illustrating how they compound non-compliance. Clinical impacts include MDR/XDR-TB, prolonged treatment, community transmission. Conclusions: arises from complex interplay individual, socio-economic, healthcare-related factors. emphasizes importance integrated develop context-specific improving adherence, reducing burden, guiding future policy.
Language: Английский