Revealing the Synergistic Anticancer Efficacy of Curcumin and Iota‐Carrageenan‐Stabilized Silver Nanoparticles Derived From Solieria robusta DOI Creative Commons

Ganesan Mohan,

Anpilov A.M.,

Mohammad Sibtain Kadri

et al.

Scientifica, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

In this study, a red seaweed ( Solieria robusta ) containing ι ‐carrageenan (Carr) was used for nanoparticles (NPs) synthesis using silver (Ag) ions. Initially, the ‐Carr extracted from S. alkali method. The Carr fractionated into 3 fractions and > 14 kDa fraction showing high yield with maximum sulfate content characterized Fourier transform infrared (FT‐IR) as AgNPs synthesis. synthesized CarrAgNPs were again curcumin (Cur) encapsulation. cytotoxicity of Carr, Cur, CarrAgNPs, CurCarrAgNPs evaluated HeLa cell lines by MTT assay. UV‐visible spectroscopy, well FT‐IR XRD analysis. spectrum confirms characteristic SPR bands recorded between 344 490 nm broad peak at 430 nm. shape NPs is spherical, arranged in order seven per chain. characteristics confirm orthorhombic crystal structure these NPs. Remarkably, Cur‐loaded demonstrate potent anticancer properties reduction viability after 24 h 200 μ g/mL pH 7.4 an assay medium. A significant increase cancer concentrations CurCarrAgNPs, confirming its less diffusion dissolution bioavailability due to lipophilic Cur encapsulation, whereas increased proportionately increasing that direct relation size, dissolution, on basis death introduction 7.4. results suggest potential drug delivery selective biomedical product developments. This study highlights versatility effectiveness therapy enhancing efficacy therapeutic interventions targeted delivery.

Language: Английский

Synthesis, characterization, and photocatalytic activities of green sol-gel ZnO nanoparticles using Abelmoschus esculentus and Salvia officinalis: A comparative study versus co-precipitation-synthesized nanoparticles DOI Creative Commons

Zakie Aalami,

Mohammadsaleh Hoseinzadeh, Parsa Hosseini Manesh

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(2), P. e24212 - e24212

Published: Jan. 1, 2024

BackgroundThe development of green chemistry methods involving plant-based nanoparticle synthesis presents an affordable and eco-friendly approach for wastewater treatment color removal. This study aimed to synthesize ZnO nanoparticles using the sol-gel method with Salvia officinalis Abelmoschus esculentus plants, examining their photocatalytic efficiency organic dye removal.MethodsTo compare properties nanoparticles, another type ZnO-NPs was synthesized co-precipitation method. The characterization performed thermogravimetric analysis (TGA-DTG), X-ray diffraction (XRD), Dynamic Light Scattering (DLS), Zeta potential (ZP), field emission scanning electron microscopy (FE-SEM), Energy Dispersive (EDX), Fourier transform infrared spectroscopy (FTIR), UV–Vis spectrophotometry.ResultsBased on XRD results, average crystalline size calculated Debye-Scherer equation S. at 22.99 nm A. 29.79 nm, 18.83 nm. FE-SEM images showed spherical nanoparticles. Photocatalytic were investigated remove methylene blue in presence UV light. pH 10 identified as best pH, which had highest percentage degradation. All three types tested by up 360 min optimize dyeing time. For esculentus, removal occurred first 90 (41.0 %), between 75 (86.9 chemically 30 45 (100 %).ConclusionsIn conclusion, MB degradation capacity belonged followed

Language: Английский

Citations

25

"Green synthesis of zinc oxide nanoparticles: Eco-friendly advancements for biomedical marvels" DOI Creative Commons

J. Nandhini,

Karthikeyan Elumalai, S. Rajeshkumar

et al.

Resources Chemicals and Materials, Journal Year: 2024, Volume and Issue: 3(4), P. 294 - 316

Published: June 1, 2024

This article explores an in-depth analysis of eco-friendly green synthesis methods to manufacture zinc oxide nanoparticles (ZnO NPs). Although chemical and/or physical approaches may initially provide better results, in the long term, a biological approach using or natural pathways plant extracts, enzymes, and microbes be more cost-effective. review addresses various techniques their potential biomedical applications, elucidating mechanisms. Additionally, highlights pivotal role ZnO NPs diabetes, cancer, wound healing, drug delivery, other marvels. Overall, it importance green-synthesized building future sustainable breakthroughs.

Language: Английский

Citations

16

Sustainable environmental-based synthesis of zinc oxide nanoparticles using para rubber leaf extract for photocatalytic degradation of organic pollutants and microbial control in wastewater treatment DOI

Pattarawadee Maijan,

Tassanai Waen‐ngoen, Sumetha Suwanboon

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 162, P. 112086 - 112086

Published: Jan. 19, 2024

Language: Английский

Citations

13

Eco-friendly fabrication of CdO nanoparticles using Polyalthia longifolia leaves extract for antibacterial and electrochemical sensing studies DOI
Suresh Ghotekar,

C.R. Ravikumar,

Ankush Chauhan

et al.

Journal of Sol-Gel Science and Technology, Journal Year: 2024, Volume and Issue: 110(1), P. 221 - 232

Published: March 6, 2024

Language: Английский

Citations

13

Honey mediated synthesis of zinc oxide nanoparticles, and evaluation of antimicrobial, antibiofilm activities against multidrug resistant clinical bacterial isolates DOI

Sudhakarachari Atapakala,

Siva Sankar Sana,

Balaji Kuppam

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: 135, P. 110 - 121

Published: Jan. 10, 2024

Language: Английский

Citations

11

Green Synthesis of Zinc Oxide Nanoparticles: Preparation, Characterization, and Biomedical Applications - A Review DOI Creative Commons
Mohamed T. El‐Saadony, Guihong Fang, Si Yan

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 12889 - 12937

Published: Dec. 1, 2024

Abstract: Over the last decade, biomedical nanomaterials have garnered significant attention due to their remarkable biological properties and diverse applications in biomedicine. Metal oxide nanoparticles (NPs) are particularly notable for wide range of medicinal uses, including antibacterial, anticancer, biosensing, cell imaging, drug/gene delivery. Among these, zinc (ZnO) NPs stand out versatility effectiveness. Recently, ZnO become a primary material various sectors, such as pharmaceutical, cosmetic, antimicrobials, construction, textile, automotive industries. can generate reactive oxygen species induce cellular apoptosis, thus underpinning potent anticancer antibacterial properties. To meet growing demand, numerous synthetic approaches been developed produce NPs. However, traditional manufacturing processes often involve economic environmental costs, prompting search more sustainable alternatives. Intriguingly, synthesis methods utilizing plants, plant extracts, or microorganisms emerged ideal producing These green production techniques offer medicinal, economic, environmental, health benefits. This review highlights latest advancements applications, showcasing potential revolutionize field with eco-friendly cost-effective solutions. Keywords: antimicrobial, antioxidant, synthesis, nanomedicine, nanoparticle,

Language: Английский

Citations

9

Aspects of Nanotechnology for COVID-19 Vaccine Development and Its Delivery Applications DOI Creative Commons
Pranav Kumar Prabhakar, Navneet Khurana, Manish Vyas

et al.

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(2), P. 451 - 451

Published: Jan. 30, 2023

Coronavirus, a causative agent of the common cold to much more complicated disease such as "severe acute respiratory syndrome (SARS-CoV-2), Middle East Respiratory Syndrome (MERS-CoV-2), and Coronavirus Disease 2019 (COVID-19)", is member coronaviridae family contains positive-sense single-stranded RNA 26-32 kilobase pairs. COVID-19 has shown very high mortality morbidity imparted significantly impacted socioeconomic status. There are many variants SARS-CoV-2 that have originated from mutation genetic material original coronavirus. This raised demand for efficient treatment/therapy manage newly emerged infections successfully. However, different types vaccines been developed administered patients but need attention because not under complete control. In this article, currently nanotechnology-based explored, inactivated virus vaccines, mRNA-based DNA-based S-protein-based virus-vectored etc. One important aspects their administration inside host body wherein nanotechnology can play crucial role. Currently, than 26 vaccine candidates in various phases clinical trials. Nanotechnology one growing fields drug discovery delivery also be used tackling ways design develop tools strategies detection, diagnosis, therapeutic development protect against COVID-19. The instruments speedy, precise, sensitive fabrication potent sanitizers, extracellular antigenic components or into human tissues, antiretroviral medicines organism management. Herein, we discuss application challenges opportunities approach.

Language: Английский

Citations

17

Salvia coccinea Buc'hoz ex Etl. Leaf extract mediated synthesis of zinc oxide nanoparticles: Assessment of antimicrobial, antioxidant and anticancer activity DOI
Dharmalingam Kirubakaran,

Kuppusamy Selvam,

Govindaraj Bagyalakshmi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105662 - 105662

Published: April 16, 2024

Language: Английский

Citations

8

A review on biogenic synthesized zinc oxide nanoparticles: synthesis, characterization, and its applications DOI
Aklilu Melese,

Walelign Wubet,

Abdu Hussen

et al.

Reviews in Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 44(3), P. 303 - 321

Published: Jan. 1, 2024

Abstract Nanotechnology is the most innovative field of twenty-first century. Worldwide, intensive research being done to commercialize nano products. Due their unique or improved physical and chemical properties relative bulk material, nanomaterials, especially nanoparticles have seen an enormous interest over past few decades. As environmentally benign alternative are currently produced “biologically” by means plant microorganism-mediated synthesis. its outstanding biocompatibility, affordability, low toxicity, cost-effectiveness, ZnO NPs emerged as one widely used metal oxide in various applications. Interestingly, due multiple medical, health, environmental, economic advantages, green technique synthesis employing materials has been discovered be suitable for production nanoparticles. A variety characterization methods assess characteristics with strategies, including X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission (TEM), Fourier-transform infrared spectroscopy (FTIR), UV–Vis others. The value these techniques reveals important information about structural, morphological, optical NPs. In order support future biomedical other research, this review provides overview recent developments a focus on natural sources such plants, bacteria, fungi, algae well characterizations, applications, including, antimicrobial, anticancer, antioxidant, photocatalytic, anti-inflammatory, anti-diabetics, anti-aging

Language: Английский

Citations

7

Phytochemical fabrication of ZnO nanoparticles and their antibacterial and anti-biofilm activity DOI Creative Commons

Hussain Udayagiri,

Siva Sankar Sana,

Lakshman Kumar Dogiparthi

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Aug. 24, 2024

The synthesis of metal nanoparticles through bio-reduction is environmentally benign and devoid impurities, which very important for biological applications. This method aims to improve ZnO nanoparticle's antibacterial anti-biofilm activity while reducing the amount hazardous chemicals used in nanoparticle production. assembly zinc oxide (ZnO NPs) presented via an aqueous nitrate solution using Echinochloacolona (E. colona) plant leaf extract comprising various phytochemical components such as phenols, flavonoids, proteins, sugars. synthesized nano NPs are characterized by UV–visible spectrophotometer (UV–vis), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (X-RD), scanning electron microscopy (SEM), transmission (TEM) elemental composition energy-dispersive x-ray (EDX). formation biosynthesized was confirmed absorbance at 360–370 nm UV–vis spectrum. average crystal size particles found be 15.8 nm, calculated from XRD. SEM TEM analysis prepared spherical hexagonal shaped nanoparticles. showed against Escherichia coli Klebsiella pneumoniae with largest zone inhibition (ZOI) 17 18 mm, respectively, disc diffusion method. Furthermore, exhibited significant a dose-dependent manner selected bacterial strains, thus suggesting that can deployed prevention infectious diseases also food preservation.

Language: Английский

Citations

6