Revealing the Synergistic Anticancer Efficacy of Curcumin and Iota‐Carrageenan‐Stabilized Silver Nanoparticles Derived From Solieria robusta DOI Creative Commons

Ganesan Mohan,

Anpilov A.M.,

Mohammad Sibtain Kadri

et al.

Scientifica, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

In this study, a red seaweed ( Solieria robusta ) containing ι ‐carrageenan (Carr) was used for nanoparticles (NPs) synthesis using silver (Ag) ions. Initially, the ‐Carr extracted from S. alkali method. The Carr fractionated into 3 fractions and > 14 kDa fraction showing high yield with maximum sulfate content characterized Fourier transform infrared (FT‐IR) as AgNPs synthesis. synthesized CarrAgNPs were again curcumin (Cur) encapsulation. cytotoxicity of Carr, Cur, CarrAgNPs, CurCarrAgNPs evaluated HeLa cell lines by MTT assay. UV‐visible spectroscopy, well FT‐IR XRD analysis. spectrum confirms characteristic SPR bands recorded between 344 490 nm broad peak at 430 nm. shape NPs is spherical, arranged in order seven per chain. characteristics confirm orthorhombic crystal structure these NPs. Remarkably, Cur‐loaded demonstrate potent anticancer properties reduction viability after 24 h 200 μ g/mL pH 7.4 an assay medium. A significant increase cancer concentrations CurCarrAgNPs, confirming its less diffusion dissolution bioavailability due to lipophilic Cur encapsulation, whereas increased proportionately increasing that direct relation size, dissolution, on basis death introduction 7.4. results suggest potential drug delivery selective biomedical product developments. This study highlights versatility effectiveness therapy enhancing efficacy therapeutic interventions targeted delivery.

Language: Английский

Dual extracellular mycofabrication of cobalt and zinc nano metal oxides mediated by mycelial-cell free filtrate of Aspergillus sojae: Characterization and assessment of antibacterial activity DOI
Basma A. Omran, Kwang-Hyun Baek

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1300, P. 137190 - 137190

Published: Nov. 27, 2023

Language: Английский

Citations

13
Green Synthesis of ZnO and Black TiO2 Materials and Their Application in Photodegradation of Organic Pollutants DOI Creative Commons
Rab Nawaz, Habib Ullah, Abdulnoor A. J. Ghanim

et al.

ACS Omega, Journal Year: 2023, Volume and Issue: 8(39), P. 36076 - 36087

Published: Sept. 22, 2023

ZnO and black TiO2 have been selected as the most efficient materials for organic pollution abatement due to their increased efficiency when compared other materials. However, concept of green chemistry makes it desirable design synthesis approaches production. In this study, was synthesized using an environmentally safe synthetic technique with glycerol a reductant. prepared by ionic-liquid-based microwave-assisted extracts Polygonum minus. To investigate materials' potential photodegrade pollutants, methylene blue (MB) phenol were chosen model pollutants. Both found exhibit spherical morphologies mesoporous structure absorbers visible light. exhibited electron-hole pair recombination lower than that TiO2. Black discovered be anatase phase, whereas hexagonal wurtzite structure. contrast TiO2, which had surface area 239.99 m2/g particle size 28 nm, 353.11 32 nm. With degradation time 60 min, able eliminate 97.50% 40 mg/L MB. on hand, could reduce 90.0% same amount MB in min. When tested degradation, activities reduced nearly 15 25%, respectively. A detailed examination both revealed has more versatility pollutants under light irradiation.

Language: Английский

Citations

11
An Emerging Foodborne Pathogen Spotlight: A Bibliometric Analysis and Scholarly Review of Escherichia coli O157 Research DOI Creative Commons
Himanshu Jangid, Deepak Kumar, Gaurav Kumar

et al.

Antibiotics, Journal Year: 2024, Volume and Issue: 13(1), P. 60 - 60

Published: Jan. 8, 2024

Foodborne infections pose a substantial global threat, causing an estimated 600 million illnesses and resulting in approximately 420,000 deaths annually. Among the diverse array of pathogens implicated these infections, Escherichia coli (E. coli), specifically O157 strain O157), emerges as prominent pathogen associated with severe outbreaks. This study employs comprehensive bibliometric analysis scholarly review focused on E. research. The highlights significant role played by United States research domain. Further exploration underscores noteworthy contributions researcher Doyle MP, whose body work, consisting 84 documents impressive H-Index 49, reflects their impact field. Recent trends indicate discernible shift towards innovative detection methods, exemplified adoption CRISPR-CAS Loop-Mediated Isothermal Amplification. Moreover, high-throughput whole-genome sequencing techniques are gaining prominence for expeditious pathogenic strains. Scientists increasingly exploring antimicrobial agents, including phage therapy, to address challenges posed antibiotic-resistant strains, thereby addressing critical concerns related multi-drug resistance. provides vital insights into dynamic landscape It serves valuable resource researchers, policymakers, healthcare professionals dedicated mitigating outbreaks advancing public health strategies.

Language: Английский

Citations

4
Preparation of gallotannin loaded chitosan/zinc oxide nanocomposite for photocatalytic degradation of organic dye and antibacterial applications DOI
Devaraj Bharathi, Solairaj Dhanasekaran,

R. Varshini

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 243, P. 125052 - 125052

Published: May 27, 2023

Language: Английский

Citations

10
Thymoquinone loaded zinc oxide Nanoformulations synthesis, characterization and evaluation of their efficacy against carbon tetrachloride induced Hepatorenal toxicity in rats DOI
Mariam Hashim, Sumaira Anjum, Huma Mujahid

et al.

Toxicology Research, Journal Year: 2025, Volume and Issue: 14(2)

Published: March 1, 2025

Abstract Thymoquinone (THQ), a strong antioxidant and anti-inflammatory bioactive compound has been reported in numerous studies to prevent the hepatorenal toxicity caused by various xenobiotics. Similarly, zinc oxide nanoparticles (ZnONPs) have used protect against damages oxidative stress due their potent properties. The aim of this study was synthesize investigate possible protective effects THQ, ZnONPs THQ-loaded CCl4 induced albino rats. were synthesized characterized techniques. For in-vivo study, thirty rats randomly divided into five groups six each. control group received normal saline 2nd (injury group) only. 3rd (T1-group) + ZnONPs, 4th (T2-group) 5th (T3-group) ZnONPs. Renal hepatic biomarkers (total bilirubin, AST, ALT, ALP, blood urea nitrogen creatinine), lipid profiles, levels histopathological investigated. NPs showed spherical shape with an average size 16–30 nm exhibited hexagonal structures. Results that resulted decrease liver kidney as well reduction TC, TG, LDL compared THQ alone. CAT, SOD, GR DPPH-radical scavenging ability maintained at T3, which T1 T2 groups. Hepatic analysis revealed hydropic degeneration hepatocyte congestion central veins, alongside tubular cell swelling normalization renal histology In conclusion, results investigation demonstrate can act efficient protectant

Language: Английский

Citations

0
Dual role of zinc oxide nanoparticles in antifungal action against Rhizoctonia solani, biosafety and phytotoxicity concerns in crop plants DOI
Dumpapenchala Vijayreddy, A. Kandan, Pranab Dutta

et al.

Physiological and Molecular Plant Pathology, Journal Year: 2025, Volume and Issue: unknown, P. 102712 - 102712

Published: April 1, 2025

Language: Английский

Citations

0
Antibacterial, antibiofilm and larvicidal activity of silver nanoparticles synthesized from spider silk protein DOI
Anupam Mondal,

Suprity Maity,

Arghadip Mondal

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 258, P. 128775 - 128775

Published: Dec. 13, 2023

Language: Английский

Citations

8
Synthesis and characterization of Pyrus communis fruit extract synthesized ZnO NPs and assessed their anti-diabetic and anti-microbial potential DOI

Kasber Elankathirselvan,

Aafreen Fathima H,

K. Praveen

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 258, P. 119450 - 119450

Published: June 18, 2024

Language: Английский

Citations

3
Synthesis of Hemidesmus indicus-Mediated Biogenic Titanium Oxide Nanoparticles for Potential Applications in Dental Adhesive DOI

S. R. Arun Dharsaun,

Arul Prakash Francis,

R. Gayathri

et al.

Nano LIFE, Journal Year: 2024, Volume and Issue: 15(03)

Published: Aug. 27, 2024

Dental adhesive materials play a crucial role in modern dentistry, enabling the bonding of restorative to tooth structures. However, concerns about conventional agents’ potential toxicities and adverse effects have been raised. This has sparked interest exploring alternative environmentally friendly for dental applications. Hemidesmus indicus commonly known as Indian sarsaparilla, used historically Ayurvedic medicine, gained attention nanotechnology functionalizing nanoparticles. The primary objective this study is develop biogenic titanium oxide nanoparticles (H-TiO 2 NPs) using natural reducing agent further coated with curcumin, specifically material were prepared green synthesis method characterized by various techniques. biocompatibility bioactivity assessed multiple assays. synthesized root extract capped curcumin showed maximum absorbance at 302 nm 498 UV spectra. presence characteristic peaks fingerprint region FTIR spectra reveals capping on TiO NPs. monoclinic structure was displayed XRD pattern. SEM micrograph uncoated NPs exhibits spherical morphology size range around 100-140 nm. Further, EDAX HCTN elemental composition 43.7% oxygen, 33.4% carbon 22.8% Titanium. studies towards peripheral blood mononuclear cells (PBMCs) erythrocytes proved its nontoxic properties. In vitro,bioactivity revealed that exhibited significant antibacterial anti-inflammatory activity, evidenced inhibition protein denaturation. demonstrated bioactivities make them candidates results highlighted promising materials, offering antimicrobial contributes eco-friendly biocompatible use dentistry. in-depth analysis necessary fully understand their efficacy, safety long-term performance

Language: Английский

Citations

3
Unrevealing Biosynthesis of Zinc Oxide Nanoparticles Using Laggera alata Leaf Extract: Evaluation of Antioxidant, Anticholinergic, and Anti-Diabetic Properties DOI

P. Visvanathan,

Dharmalingam Kirubakaran,

M. Rajkumar

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

Laggera alata plants have emerged as a valuable resource in biomedicine. In this study, we present an environmentally friendly method for synthesizing zinc oxide nanoparticles (ZnONPs). The properties of the synthesized were analyzed using various techniques, including UV–Vis, FTIR, XRD, SEM-EDAX, and Zeta potential analysis. UV–Vis analysis confirmed successful synthesis ZnONPs with distinct absorption peak at 372 nm. FTIR spectra revealed presence functional groups, while XRD crystalline structure nanoparticles. SEM images showed spherical morphology, EDAX oxygen. was measured − 23 mV, indicating stable nanoparticle dispersion. exhibited notable antibacterial activity, inhibition zones 13 mm against S. aureus 9 E. coli. Their antioxidant demonstrated through multiple assays, DPPH, ABTS, FRAP, SOD. Additionally, explored anticholinergic antidiabetic these nanoparticles, highlighting their promising therapeutic potential. This study presents novel approach to utilizing from L. effective agents antibacterial, antioxidant, properties. These findings pave way further research development medical applications.

Language: Английский

Citations

2