Catalyzing innovation: Exploring iron oxide nanoparticles - Origins, advancements, and future application horizons

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 507, P. 215750 - 215750

Published: Feb. 29, 2024

Language: Английский

---

Advancements in enzyme immobilization on magnetic nanomaterials: toward sustainable industrial applications

RSC Advances, Journal Year: 2024, Volume and Issue: 14(25), P. 17946 - 17988

Published: Jan. 1, 2024

Enzymes are widely used in biofuels, food, and pharmaceuticals.

Language: Английский

---

Influence of Physicochemical Properties of Iron Oxide Nanoparticles on Their Antibacterial Activity

ACS Omega, Journal Year: 2024, Volume and Issue: 9(31), P. 33303 - 33334

Published: July 25, 2024

The increasing occurrence of infectious diseases caused by antimicrobial resistance organisms urged the necessity to develop more potent, selective, and safe agents. unique magnetic tunable properties iron oxide nanoparticles (IONPs) make them a promising candidate for different theragnostic applications, including Though IONPs act as nonspecific agent, their activities are directly or indirectly linked with synthesis methods, synthesizing precursors, size, shapes, concentration, surface modifications. Alteration these parameters could accelerate decelerate production reactive oxygen species (ROS). An increase in ROS role disrupts bacterial cell walls, membranes, alters major biomolecules (e.g., lipids, proteins, nucleic acids), affects metabolic processes Krebs cycle, fatty acid synthesis, ATP glycolysis, mitophagy). In this review, we will investigate antibacterial activity bare surface-modified influence physiochemical on activity. Additionally, report potential mechanism IONPs' action driving

Language: Английский

---

Recent Advances in the Development of Drug Delivery Applications of Magnetic Nanomaterials

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(7), P. 1872 - 1872

Published: July 3, 2023

With the predicted rise in incidence of cancer, there is an ever-growing need for new cancer treatment strategies. Recently, magnetic nanoparticles have stood out as promising nanostructures imaging and drug delivery systems they possess unique properties. Moreover, nanomaterials functionalized with other compounds can lead to multicomponent innovative structures synergetic performance. The incorporation chemotherapeutic drugs or RNA represents a alternative that increase efficiency reduce side effects anticancer therapy. This review presents critical overview recent literature concerning advancements field used delivery, focus on their classification, characteristics, synthesis functionalization methods, limitations, examples incorporating chemotherapeutics RNA.

Language: Английский

---

Eco-friendly fabrication of CdO nanoparticles using Polyalthia longifolia leaves extract for antibacterial and electrochemical sensing studies

Journal of Sol-Gel Science and Technology, Journal Year: 2024, Volume and Issue: 110(1), P. 221 - 232

Published: March 6, 2024

Language: Английский

---

Harnessing Magnetic Nanoparticles for the Effective Removal of Micro- and Nanoplastics: A Critical Review

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(14), P. 1179 - 1179

Published: July 11, 2024

The spread of micro- (MPs) and nanoplastics (NPs) in the environment has become a significant environmental concern, necessitating effective removal strategies. In this comprehensive scientific review, we examine use magnetic nanoparticles (MNPs) as promising technology for MPs NPs from water. We first describe issues their impact on human health. Then, fundamental principles using MNPs these pollutants will be presented, emphasizing that enable selective binding separation water sources. Furthermore, provide short summary various types have proven NPs. These include ferromagnetic coated with organic polymers, well nanocomposites nanostructures. also review properties, such saturation, size, shape, surface functionalization, stability, influence efficiency. Next, different methods utilizing discuss advantages, limitations, potential further development detail. final part an overview existing studies results demonstrating effectiveness address challenges need to overcome, nanoparticle optimization, process scalability, recycling after completion process. This offers extensive insights into With improved understanding advanced materials methods, can play crucial role addressing preserving clean healthy environment. novelty article is emphasis detailed advantages disadvantages mentioned application. Additionally, large number publications field provided.

Language: Английский

---

Iron oxide nanoparticles coated with bioactive materials: a viable theragnostic strategy to improve osteosarcoma treatment

Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)

Published: Jan. 30, 2025

Abstract Osteosarcoma (OS) is distinguished as a high-grade malignant tumor, characterized by rapid systemic metastasis, particularly to the lungs, resulting in very low survival rates. Understanding complexities of tumor development and mutation need hour for advancement targeted therapies cancer care. A significant innovation this area use nanotechnology, specifically nanoparticles, tackle various challenges treatment. Iron oxide nanoparticles stand out both therapeutic diagnostic applications, offering versatile platform drug delivery, hyperthermia, magneto-thermal therapy, combinational therapy using modulation ferroptosis pathways. These are easy synthesize, non-toxic, biocompatible, display enhanced circulation time within system. They can also be easily conjugated anti-cancer drugs, targeting agents, or genetic vectors that respond specific stimuli pH changes. The surface functionalization these bioactive molecules unveils promising effective nanoparticle system assisting osteosarcoma therapy. This review will summarize current conventional their disadvantages, synthesis modification iron documented literature, cellular uptake mechanism, with focus on natural biomaterials application strategies towards management osteosarcoma. compiles translational future prospects must addressed clinical advancements based treatment future. Graphical abstract

Language: Английский

---

Construction and Characterization of 5,6-O-Isopropylidene-L-Ascorbic Acid-Loaded Silver and Manganese Dioxide Nanoparticles: Cytotoxicity Study, Antibacterial, and Antioxidant Activities

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130517 - 130517

Published: Feb. 1, 2025

Language: Английский

---

Cell-Membrane-Coated and Cell-Penetrating Peptide-Conjugated Trimagnetic Nanoparticles for Targeted Magnetic Hyperthermia of Prostate Cancer Cells

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(25), P. 30008 - 30028

Published: June 13, 2023

Prostate malignancy represents the second leading cause of cancer-specific death among male population worldwide. Herein, enhanced intracellular magnetic fluid hyperthermia is applied in vitro to treat prostate cancer (PCa) cells with minimum invasiveness and toxicity highly specific targeting. We designed optimized novel shape-anisotropic core-shell-shell nanoparticles (i.e., trimagnetic - TMNPs) significant magnetothermal conversion following an exchange coupling effect external alternating field (AMF). The functional properties best candidate terms heating efficiency [email protected]@CoFe2O4) were exploited surface decoration PCa cell membranes (CM) and/or LN1 cell-penetrating peptide (CPP). demonstrated that combination biomimetic dual CM-CPP targeting AMF responsiveness significantly induces caspase 9-mediated apoptosis cells. Furthermore, a downregulation cycle progression markers decrease migration rate surviving observed response TMNP-assisted hyperthermia, suggesting reduction aggressiveness.

Language: Английский

---

Current Advances in Nanotheranostics for Molecular Imaging and Therapy of Cardiovascular Disorders

Molecular Pharmaceutics, Journal Year: 2023, Volume and Issue: 20(10), P. 4922 - 4941

Published: Sept. 12, 2023

Cardiovascular diseases (CVDs) refer to a collection of conditions characterized by abnormalities in the cardiovascular system. They are global problem and one leading causes mortality disability. Nanotheranostics implies combination diagnostic therapeutic capabilities inside single nanoscale platform that has allowed for significant advancement diagnosis therapy. These advancements being developed improve imaging capabilities, introduce personalized therapies, boost disease patient treatment outcomes. Significant progress been achieved integration within nanocarriers. In case disease, nanoparticles provide targeted delivery therapeutics, genetic material, photothermal, agents. Directing monitoring movement these may be done with pinpoint accuracy using modalities such as magnetic resonance (CMR), computed tomography (CT), positron emission (PET), photoacoustic/ultrasound, fluorescence imaging. Recently, there an increasing demand noninvasive multimodal nanotheranostic platforms. platforms, various technologies optical integrated into nanoparticle. This helps acquiring more accurate descriptions provides clues diagnosis. Advances surface functionalization methods have strengthened potential application nanotheranostics this Review, we covered impact nanomedicine on CVDs. Additionally, discussed recently CVDs Moreover, CMR, CT, PET, ultrasound, photoacoustic discussed. We limited our discussion nanomaterials based clinical trials their patents.

Language: Английский

---