Machine learning applications for electrospun nanofibers: a review

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(31), P. 14095 - 14140

Published: July 30, 2024

Abstract Electrospun nanofibers have gained prominence as a versatile material, with applications spanning tissue engineering, drug delivery, energy storage, filtration, sensors, and textiles. Their unique properties, including high surface area, permeability, tunable porosity, low basic weight, mechanical flexibility, alongside adjustable fiber diameter distribution modifiable wettability, make them highly desirable across diverse fields. However, optimizing the properties of electrospun to meet specific requirements has proven be challenging endeavor. The electrospinning process is inherently complex influenced by numerous variables, applied voltage, polymer concentration, solution flow rate, molecular weight polymer, needle-to-collector distance. This complexity often results in variations nanofibers, making it difficult achieve desired characteristics consistently. Traditional trial-and-error approaches parameter optimization been time-consuming costly, they lack precision necessary address these challenges effectively. In recent years, convergence materials science machine learning (ML) offered transformative approach electrospinning. By harnessing power ML algorithms, scientists researchers can navigate intricate space more efficiently, bypassing need for extensive experimentation. holds potential significantly reduce time resources invested producing wide range applications. Herein, we provide an in-depth analysis current work that leverages obtain target nanofibers. examining work, explore intersection ML, shedding light on advancements, challenges, future directions. comprehensive not only highlights processes but also provides valuable insights into evolving landscape, paving way innovative precisely engineered various Graphical abstract

Language: Английский

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Electrospun nanofibers of collagen and chitosan for tissue engineering and drug delivery applications: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 296, P. 139663 - 139663

Published: Jan. 8, 2025

Language: Английский

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Potential of Chitosan/Gelatin-Based Nanofibers in Delivering Drugs for the Management of Varied Complications: A Review

Polymers, Journal Year: 2025, Volume and Issue: 17(4), P. 435 - 435

Published: Feb. 7, 2025

Drug delivery systems have revolutionized traditional drug administration methods by addressing various challenges, such as enhancing solubility, prolonging effectiveness, minimizing adverse effects, and preserving potency. Nanotechnology-based systems, particularly nanoparticles (NPs) nanofibers (NFs), emerged promising solutions for biomedicine delivery. NFs, with their ability to mimic the porous fibrous structures of biological tissues, garnered significant interest in drug-delivering applications. Biopolymers gelatin (Ge) chitosan (CH) gained much more attention due biocompatibility, biodegradability, versatility biomedical CH exhibits exceptional anti-bacterial activity, wound healing capabilities, whereas Ge provides good biocompatibility cell adhesion properties. Ge/CH-based NFs stimulate cellular connections facilitate tissue regeneration owing structural resemblance extracellular matrix. This review explores additive preparation, including electrospinning, force pinning, template synthesis, focusing on electrospinning factors influencing fiber structure. The properties CH, role release, formulation strategies, characterization techniques electrospun fibers are discussed. Furthermore, this addresses applications delivering active moieties management orthopedics regulatory considerations, along challenges related them. Thus, aims provide a comprehensive overview potential

Language: Английский

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Recent progress in biopolymer-based electrospun nanofibers and their potential biomedical applications: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 293, P. 139426 - 139426

Published: Jan. 1, 2025

Language: Английский

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Advancements in Protein-Based Bionanocomposites for Targeted and Controlled Drug Delivery Systems: A Comprehensive Review

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106698 - 106698

Published: Feb. 1, 2025

Language: Английский

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Resistive gas sensors based on inorganic nanotubes: a review

Journal of Alloys and Compounds, Journal Year: 2025, Volume and Issue: unknown, P. 179585 - 179585

Published: March 1, 2025

Language: Английский

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Chitosan: modification and biodegradability of by-products

Polymer Bulletin, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 30, 2024

Language: Английский

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Electrospun drug‐loaded scaffolds for nervous system repair

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2024, Volume and Issue: 16(3)

Published: May 1, 2024

Abstract Nervous system injuries, encompassing peripheral nerve injury (PNI), spinal cord (SCI), and traumatic brain (TBI), present significant challenges to patients' wellbeing. Traditional treatment approaches have limitations in addressing the complexity of neural tissue regeneration require innovative solutions. Among emerging strategies, implantable materials, particularly electrospun drug‐loaded scaffolds, gained attention for their potential simultaneously provide structural support controlled release therapeutic agents. This review provides a thorough exploration recent developments design application scaffolds nervous repair. The electrospinning process offers precise control over scaffold characteristics, including mechanical properties, biocompatibility, topography, crucial creating conducive environment regeneration. large surface area resulting fibrous networks enhances biomolecule attachment, influencing cellular behaviors such as adhesion, proliferation, migration. Polymeric materials demonstrate versatility accommodating spectrum therapeutics, from small molecules proteins. enables tailored interventions accelerate neuroregeneration mitigate inflammation at site. A critical aspect this is examination interplay between properties pharmacological effects, emphasizing importance optimizing both aspects enhanced outcomes. Drawing upon latest advancements field, we discuss promising outcomes preclinical studies using repair, well future perspectives considerations implementation. article categorized under: Implantable Materials Surgical Technologies > Nanomaterials Implants Nanotechnology Tissue Repair Replacement Therapeutic Approaches Drug Discovery Emerging

Language: Английский

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Advancements, functionalization techniques, and multifunctional applications in biomedical and industrial fields of electrospun pectin nanofibers: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141964 - 141964

Published: March 1, 2025

Language: Английский

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The Utilization of Biopolymer Hydrogels to Encapsulate and Protect Probiotics in Foods

Process Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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